Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Ub, Ubiquitin"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 695-716 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Diarrhea is one of the most common illnesses and is often caused by bacterial infection. Recently, we have shown that human Na+/H+ exchanger NHE3 (hNHE3), but not non-human NHE3s, interacts with the E3 ubiquitin ligase Nedd4-2. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d39e72e4258b61df22d22d51d780ec
https://doi.org/10.1016/j.jcmgh.2021.11.006
https://doi.org/10.1016/j.jcmgh.2021.11.006
Autor:
Arun Upadhyay
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2995-3014 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Cells have different sets of molecules for performing an array of physiological functions. Nucleic acids have stored and carried the information throughout evolution, whereas proteins have been attributed to performing most of the cellular functions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5576b50a2ff37b0f37fd10602f606f6c
http://www.sciencedirect.com/science/article/pii/S2211383521000095
http://www.sciencedirect.com/science/article/pii/S2211383521000095
Autor:
Marta Acchioni, Anna Lisa Remoli, Angela Battistini, Robert Clarke, Chiara Acchioni, Giulia Marsili, Roberto Orsatti, Edvige Perrotti, Marco Sgarbanti
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 10, Pp 459-469 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Interferon Regulatory Factors (IRFs) are key regulators of immunity, cell survival and apoptosis. IRF transcriptional activity and subcellular localization are tightly regulated by posttranscriptional modifications including phosphorylation. The IκB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90dc31ce8201d10ab9e5e10769229024
http://www.sciencedirect.com/science/article/pii/S1476558620301354
http://www.sciencedirect.com/science/article/pii/S1476558620301354
Autor:
Xiao-Jing Shi, Kai Sun, Zhong-Hua Li, Yun-Dong Fu, Bin Yu, Tao-Qian Zhao, Hong-Min Liu, Jimin Guo, Zhen-Zhen Liu, Ting Cheng
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1476-1491 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1476-1491 (2020)
Ubiquitin specific peptidase 28 (USP28) is closely associated to the occurrence and development of various malignancies, and thus has been validated as a promising therapeutic target for cancer therapy. To date, only few USP28 inhibitors with moderat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31004bae2f224ef9b82793cacf7cc8eb
https://doi.org/10.1016/j.apsb.2019.12.008
https://doi.org/10.1016/j.apsb.2019.12.008
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta pharmaceutica Sinica. B, vol 10, iss 1
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 42-60 (2020)
Acta pharmaceutica Sinica. B, vol 10, iss 1
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 42-60 (2020)
The hepatic endoplasmic reticulum (ER)-anchored cytochromes P450 (P450s) are mixed-function oxidases engaged in the biotransformation of physiologically relevant endobiotics as well as of myriad xenobiotics of therapeutic and environmental relevance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b693f8b63f9fc633d41381151847be33
https://doi.org/10.1016/j.apsb.2019.11.002
https://doi.org/10.1016/j.apsb.2019.11.002
Autor:
Andrew Dickson, Benjamin R. Stromberg, Christine Insinna, Matthew K. Summers, Yosup Rhee, Adrian E. Torres, Debjani Pal, Christopher J. Westlake, Mayank Singh, Amy C. Burrows
Publikováno v:
The Journal of Biological Chemistry
The deubiquitinating enzyme USP37 is known to contribute to timely onset of S phase and progression of mitosis. However, it is not clear if USP37 is required beyond S-phase entry despite expression and activity of USP37 peaking within S phase. We hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eedf7a343128548aa738f8cb79c88d9
http://europepmc.org/articles/PMC8487067
http://europepmc.org/articles/PMC8487067
Publikováno v:
Redox Biology, Vol 45, Iss, Pp 102047-(2021)
Redox Biology
Redox Biology
The contribution of the Ubiquitin-Proteasome System (UPS) to mitophagy has been largely attributed to the E3 ubiquitin ligase Parkin. Here we show that in response to the oxidative stress associated with hypoxia or the hypoxia mimic CoCl2, the damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36dfe538d50d5a83c423b9365c089170
http://www.sciencedirect.com/science/article/pii/S2213231721002068
http://www.sciencedirect.com/science/article/pii/S2213231721002068
Autor:
Juliana Bragazzi Cunha, Jordan A. Shavit, Herbert L. Bonkovsky, Dhiman Maitra, Jared S. Elenbaas, M. Bishr Omary
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 4, Pp 535-548 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Genetic porphyrias comprise eight diseases caused by defects in the heme biosynthetic pathway that lead to accumulation of heme precursors. Consequences of porphyria include photosensitivity, liver damage and increased risk of hepatocellular carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0af3ebb574e4ee6cf3f3b54e0ba117c
https://doi.org/10.1016/j.jcmgh.2019.06.006
https://doi.org/10.1016/j.jcmgh.2019.06.006
Publikováno v:
The Journal of Biological Chemistry
Marafiviruses are capable of persistent infection in a range of plants that have importance to the agriculture and biofuel industries. Although the genomes of a few of these viruses have been studied in-depth, the composition and processing of the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cc6480ae05ba1150d64902fd7fd986
https://pubmed.ncbi.nlm.nih.gov/34265303
https://pubmed.ncbi.nlm.nih.gov/34265303
Autor:
Gabriel Talaia, Margarida Casal, Hernâni Gerós, Sandra Paiva, Rosana Maria Abreu Alves, Cláudia Barata-Antunes, Robert Mans
Publikováno v:
Computational and Structural Biotechnology Journal, 19
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1713-1737 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1713-1737 (2021)
Plasma membrane transporters play pivotal roles in the import of nutrients, including sugars, amino acids, nucleobases, carboxylic acids, and metal ions, that surround fungal cells. The selective removal of these transporters by endocytosis is one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632ee65f13d8bd8b6a66921459f5d65f
https://hdl.handle.net/1822/72047
https://hdl.handle.net/1822/72047
