The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway

Autor: Patrícia Maria Siqueira dos Passos, Natália Borges Simaroli, Felipe R. Teixeira, Tycho E. T. Mevissen, Joice S. Oliveira, Marcelo D. Gomes, Heike Laman, Valentine Spagnol, Camila R.S.T.B. de Correia, Suzanne J. Randle, David Komander, Caio Almeida Batista de Oliveira, Ana C. Medeiros

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Biochimica et Biophysica Acta. General Subjects

Background Ubiquitously eXpressed Transcript isoform 2 (UXT—V2) is a prefoldin-like protein involved in NF-κB signaling, apoptosis, and the androgen and estrogen response. UXT-V2 is a cofactor in the NF-κB transcriptional enhanceosome, and its kn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f95f5b0ac07eecea9d520eac11761e
https://www.repository.cam.ac.uk/handle/1810/310834