Zobrazeno 1 - 10
of 29
pro vyhledávání: '"UUO (unilateral ureteral obstruction)"'
Autor:
Sturla M. Grøndal, Magnus Blø, Linn I. H. Nilsson, Austin J. Rayford, Akil Jackson, Gro Gausdal, James B. Lorens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe incidence of chronic kidney disease (CKD) is increasing, in parallel with risk factors including obesity and diabetes mellitus. AXL plays a central role in CKD, providing a rationale to evaluate clinical AXL targeting agents.MethodsTo
Externí odkaz:
https://doaj.org/article/fb0ccd45b79b4d14af7b2e872d22b624
Autor:
Hang-Xing Yu, Wei Lin, Kang Yang, Li-Juan Wei, Jun-Li Chen, Xin-Yue Liu, Ke Zhong, Xin Chen, Ming Pei, Hong-Tao Yang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Hirudin has been widely used in the treatment of antifibrosis. Previous studies have shown that hirudin can effectively improve the clinical remission rate of chronic kidney disease. However, the mechanism of its renal protection has not
Externí odkaz:
https://doaj.org/article/d4a8a85b21a7403387692ae2c3dd43e2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 322-339 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Fibrosis is a pathological reparative process that can occur in most organs and is responsible for nearly half of deaths in the developed world. Despite considerable research, few therapies have proven effective and been approved clinically for treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31e277e49b3a3364e9726d531259ad4
https://doi.org/10.1016/j.apsb.2020.09.001
https://doi.org/10.1016/j.apsb.2020.09.001
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 835-847 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 835-847 (2021)
Localized delivery, comparing to systemic drug administration, offers a unique alternative to enhance efficacy, lower dosage, and minimize systemic tissue toxicity by releasing therapeutics locally and specifically to the site of interests. Herein, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64e18f3ceec35a47174c01834804b93
http://europepmc.org/articles/PMC7982499
http://europepmc.org/articles/PMC7982499
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Manveen Kaur Jawanda, Sonia Gupta
Publikováno v:
The Saudi Dental Journal
Saudi Dental Journal, Vol 33, Iss 7, Pp 413-423 (2021)
Saudi Dental Journal, Vol 33, Iss 7, Pp 413-423 (2021)
Background Oral submucous fibrosis (OSMF) is one of the common oral potentially malignant disorders that can result in severe morbidity. Depending upon the stage of disease, multiple management therapies exist which include medicinal and surgical app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20299deb0cdb787e8d78c8215180ee9b
https://pubmed.ncbi.nlm.nih.gov/34803281
https://pubmed.ncbi.nlm.nih.gov/34803281
Autor:
Diego Rodríguez-Puyol, Laura García-Bermejo, Ricardo Luiz Ramos, Santiago Lamas, Verónica Miguel
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Redox Biology
Redox Biology, Vol 40, Iss, Pp 101851-(2021)
instname
Redox Biology
Redox Biology, Vol 40, Iss, Pp 101851-(2021)
Excessive accumulation of extracellular matrix (ECM) is the hallmark of fibrotic diseases. In the kidney, it is the final common pathway of prevalent diseases, leading to chronic renal failure. While cytokines such as TGF-β play a fundamental role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f21a82192fc7b9a84acd0c9fd1b1d9
http://hdl.handle.net/10261/270587
http://hdl.handle.net/10261/270587
Autor:
Françoise Poirier, Etienne Gayat, Claude Delcayre, Jean-Marie Launay, Thibault Michel, Bocar Kane, Satoshi Kinugasa, Alain Cohen-Solal, Magali Genest, Matthieu Legrand, Maxime Coutrot, Louis Boutin, Sophie Vandermeersch, Christos E. Chadjichristos, Alexandre Mebazaa, Mathilde Prud’homme, Ravindra L. Mehta, Niki Prakoura, Jane-Lise Samuel
Publikováno v:
JACC. Basic to translational science, vol 4, iss 6
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 6, Pp 717-732 (2019)
JACC : Basic to Translational Science
JACC : Basic to Translational Science, Elsevier on behalf of the American College of Cardiology Foundation, 2019, 4, pp.717-732. ⟨10.1016/j.jacbts.2019.06.005⟩
JACC : Basic to Translational Science, 2019, 4 (6), pp.717-732. ⟨10.1016/j.jacbts.2019.06.005⟩
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 6, Pp 717-732 (2019)
JACC : Basic to Translational Science
JACC : Basic to Translational Science, Elsevier on behalf of the American College of Cardiology Foundation, 2019, 4, pp.717-732. ⟨10.1016/j.jacbts.2019.06.005⟩
JACC : Basic to Translational Science, 2019, 4 (6), pp.717-732. ⟨10.1016/j.jacbts.2019.06.005⟩
Visual Abstract
Highlights • In 2 different mouse models, AKI increased Gal-3 expression and induced cardiac dysfunction, cardiac and systemic inflammation, cardiac macrophage infiltration, and fibrosis. • Cardiac consequences of AKI were de
Highlights • In 2 different mouse models, AKI increased Gal-3 expression and induced cardiac dysfunction, cardiac and systemic inflammation, cardiac macrophage infiltration, and fibrosis. • Cardiac consequences of AKI were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948d78c938448798fca803e3c711b7ad
https://escholarship.org/uc/item/37f467d5
https://escholarship.org/uc/item/37f467d5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.