Zobrazeno 1 - 10
of 1 395
pro vyhledávání: '"UTX"'
Autor:
Dezhi Chen, Bo Cai, Yingying Zhu, Yimin Ma, Xiaoting Yu, Jieqi Xiong, Jiaying Shen, Weiwei Tie, Yisheng Zhang, Fei Guo
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background The intriguing connection between selenium and cancer resembles a captivating puzzle that keeps researchers engaged and curious. While selenium has shown promise in reducing cancer risks through supplementation, its interaction wi
Externí odkaz:
https://doaj.org/article/499d312dc2c3455284669e2d3893a912
Autor:
Qianyi Ming, Jiejie Liu, Zijian Lv, Tiance Wang, Runjia Fan, Yan Zhang, Meixia Chen, Yingli Sun, Weidong Han, Qian Mei
Publikováno v:
MedComm, Vol 5, Iss 9, Pp n/a-n/a (2024)
Abstract Natural killer (NK) cells play a crucial role in both innate immunity and the activation of adaptive immunity. The activating effect of Mn2+ on cyclic GMP‐AMP(cGAS)–stimulator of interferon genes (STING signaling has been well known, but
Externí odkaz:
https://doaj.org/article/312911f59b034761b8632e405fd43775
Autor:
Hui-Qing Zhang, Fanyang Kong, Xiangyu Kong, Tingting Jiang, Muyuan Ma, Shaojiang Zheng, Junli Guo, Keping Xie
Publikováno v:
Genes and Diseases, Vol 11, Iss 2, Pp 921-934 (2024)
Ubiquitously transcribed tetratricopeptide repeat on chromosome X (UTX), also known as lysine (K)-specific demethylase 6A (KDM6A), functions as a tumor suppressor gene or oncogene depending on the tumor type and context. However, its tumor-suppressiv
Externí odkaz:
https://doaj.org/article/2d0af248b54c42868ac82ae293f75538
Autor:
Yudong Liu, Zixiang Luo, Yong Xie, Yi Sun, Feifei Yuan, Liyuan Jiang, Hongbin Lu, Jianzhong Hu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Vascular endothelial cells are pivotal in the pathophysiological progression following spinal cord injury (SCI). The UTX (Ubiquitously Transcribed Tetratripeptide Repeat on Chromosome X) serves as a significant regulator of endoth
Externí odkaz:
https://doaj.org/article/2eca831b7dcd4cc09bf1c05aa9a6ba40
Autor:
Dakui Luo, Min Chen, Qingguo Li, Kangjunjie Wang, Kaihua Wang, Junqiang Li, Guoxiang Fu, Zezhi Shan, Qi Liu, Yufei Yang, Lei Liang, Yanlei Ma, Yi Qin, Jun Qin, Daming Gao, Xinxiang Li
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-21 (2023)
Abstract Background UTX (encoded by KDM6A), a histone demethylase for H3K27me2/3, is frequently mutated in human cancers. However, its functional and regulatory mechanisms in colorectal cancer (CRC) remain unclear. Methods Immunohistochemistry staini
Externí odkaz:
https://doaj.org/article/8576dd92d49d41369206bcd4d1541e7a
Autor:
Wei Peng, Yong Xie, Zixiang Luo, Yudong Liu, Jiaqi Xu, Chengjun Li, Tian Qin, Hongbin Lu, Jianzhong Hu
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Macrophages polarized to the M2 subtype after spinal cord injury (SCI) are beneficial for promoting neurological recovery. The crosstalk between endothelial cells (ECs) and macrophages is crucial for the imbalance between proinflammatory and
Externí odkaz:
https://doaj.org/article/9edbcef10d914d85b9636257e888e707
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
The histone H3K27 demethylase, UTX/KDM6A, plays a critical role in the early development of vertebrates, and mutations are frequently found in various cancers. Several studies on developmental and cancer biology have focused on preferential transcrip
Externí odkaz:
https://doaj.org/article/ac19b9687676421585622fd8dc156a70
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