Zobrazeno 1 - 10
of 1 019
pro vyhledávání: '"USP7"'
Autor:
Guiping He, Sha Sha, Jiaji He, Xi Zhang, Qing Jin, Tao Zhao, Sheng Jin, Nitesh Shrestha, Hongxia Li, Qiu Chen, Qiang Xue
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Our previous study demonstrated that microRNA-409-5p (miR-409-5p) and its target ubiquitin-specific protease 7 (USP7) were involved in hypoxia-induced cardiomyocyte injury and ischemic left ventricular remodeling (LVR) in rats. Th
Externí odkaz:
https://doaj.org/article/66a1f5a6e95648d2a9dac9b294b3f1a8
Autor:
Yadong Yin, Yujie Li, Boyi Ma, Chenlu Ren, Shuhua Zhao, Jia Li, Yun Gong, Hong Yang, Jibin Li
Publikováno v:
Advanced Science, Vol 11, Iss 43, Pp n/a-n/a (2024)
Abstract Mitochondrial‐nuclear communication plays a vital role in maintaining cellular homeostasis. MOTS‐c, a short peptide derived from the 12S rRNA of mitochondrial DNA, has been suggested as a retrograde mitochondrial signal. Although recent
Externí odkaz:
https://doaj.org/article/08699a03b5ef4291b569f2cd7e71d355
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionTP53 is one of the most frequently mutated genes among all cancers, and TP53 mutants occur more than 40% in colorectal cancers (CRCs). Accumulation of mutant p53 may augment colorectal cancer stem cells (CCSCs) phenotype and enhance color
Externí odkaz:
https://doaj.org/article/25cfc3fb838549888433cbc80315af89
Autor:
Ruyue Zhang, Daidi Zhang, Fugen Han, Xiaorui Song, Yaodong Zhang, Jie Zhang, Qingwen Zhu, Yanru Qin
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Rhabdomyosarcoma (RMS) is a rare malignancy and the most common soft tissue sarcoma in children. Vasculogenic mimicry (VM) is a novel tumor microcirculation model different from traditional tumor angiogenesis, which does not rely
Externí odkaz:
https://doaj.org/article/7ac2ae231a354a229dca0ac26734e9fa
Autor:
Yuwen Chen, Jie Gao, Mingyue Ma, Ke Wang, Fangming Liu, Feiyu Yang, Xin Zou, Zhouli Cheng, Duojiao Wu
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTT cell immunity is critical for human defensive immune response. Exploring the key molecules during the process provides new targets for T cell-based immunotherapies. CMC1 is a mitochondrial electron transport chain (ETC) complex IV chaperon
Externí odkaz:
https://doaj.org/article/3184955e760046788c6b8f370e845252
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Mendelian disorders, arising from pathogenic variations within single genetic loci, often manifest as neurodevelopmental disorders (NDDs), affecting a significant portion of the pediatric population worldwide. These disorders are marked by atypical b
Externí odkaz:
https://doaj.org/article/88078b4359684d40a5003213769bf89c
Autor:
Meiling Yan, Liyan Su, Kaile Wu, Yu Mei, Zhou Liu, Yifan Chen, Wenru Zeng, Yang Xiao, Jingfei Zhang, Guida Cai, Yunlong Bai
Publikováno v:
Pharmacological Research, Vol 205, Iss , Pp 107235- (2024)
Diabetic cardiomyopathy (DCM) is a major complication of diabetes and is characterized by left ventricular dysfunction. Currently, there is a lack of effective treatments for DCM. Ubiquitin-specific protease 7 (USP7) plays a key role in various disea
Externí odkaz:
https://doaj.org/article/9f1d8126b9494c87b02b3b41f6af000f
Autor:
Hanlin Hu, Jingyu Lu, Mingjin Xu, Jie Wang, Yeling Zhang, Shan Yang, Xiaomin Wang, Mengyuan Wang, Wenjie Xie, Wenhua Xu, Haijun Lu
Publikováno v:
Translational Oncology, Vol 45, Iss , Pp 101990- (2024)
Background: With regard to head and neck squamous cell carcinoma (HNSCC), its occurrence and advancement are controlled by genetic and epigenetic anomalies. PIWI-interacting RNAs (piRNAs) are recognized with significance in tumor, but the precise mol
Externí odkaz:
https://doaj.org/article/8255c44602514f10b3f3494f060c4e85
Autor:
Xiaoqing Guan, Yichao Wang, Wenkai Yu, Yong Wei, Yang Lu, Enyu Dai, Xiaowu Dong, Bing Zhao, Can Hu, Li Yuan, Xin Luan, Kai Miao, Bonan Chen, Xiang‐Dong Cheng, Weidong Zhang, Jiang‐Jiang Qin
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Gastric cancer (GC) presents a formidable global health challenge, and conventional therapies face efficacy limitations. Ubiquitin‐specific protease 7 (USP7) plays pivotal roles in GC development, immune response, and chemo‐resistance, m
Externí odkaz:
https://doaj.org/article/309f94baa7be42939e0ccca5ef7af44d
Autor:
Jie Li, Bin Zhang, Zishan Feng, Dandan An, Zhiyuan Zhou, Chao Wan, Yan Hu, Yajie Sun, Yijun Wang, Xixi Liu, Wenwen Wei, Xiao Yang, Jingshu Meng, Mengjie Che, Yuhan Sheng, Bian Wu, Lu Wen, Fang Huang, Yan Li, Kunyu Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Glioblastoma (GBM) is the most common malignant tumor of the central nervous system. It is an aggressive tumor characterized by rapid proliferation, diffuse tumor morphology, and poor prognosis. Unfortunately, current treatments,
Externí odkaz:
https://doaj.org/article/25b0f6ad2cda40f5bc4d8585391599e1