Zobrazeno 1 - 10
of 51
pro vyhledávání: '"USP37"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 528-541 (2021)
Obstructive sleep apnea-hypopnea (OSAH) is correlated with an increased incidence of lung cancer. In our study, we explored the functional roles of microRNAs (miRNAs) in lung cancer patients that were complicated with OSAH involving the deubiquitinat
Externí odkaz:
https://doaj.org/article/b06a2d25eb044a63923172a04ac91d7f
Publikováno v:
Molecules, Vol 28, Iss 6, p 2441 (2023)
Diffuse Large B-Cell Lymphoma (DLBCL) is the most common form of non-Hodgkin’s lymphoma (NHL). Elevated expression of c-MYC in DLBCL is associated with poor prognosis of the disease. In different cancers, c-MYC has been found regulated by different
Externí odkaz:
https://doaj.org/article/a4d804fa5c864f9cae5da9ea4373c619
Publikováno v:
Frontiers in Genetics, Vol 10 (2020)
Snail is a prominent epithelial–mesenchymal transition (EMT) transcription factor and promotes metastasis. However, Snail protein is unstable and is quickly degraded through ubiquitination-mediated proteasome pathway. Deubiquitinases prevent Snail
Externí odkaz:
https://doaj.org/article/f8ae25a8c99a4ae58d1fc404891a96f8
Autor:
Tao Qin, Bai Li, Xiaoyue Feng, Shujun Fan, Lei Liu, Dandan Liu, Jun Mao, Ying Lu, Jinfeng Yang, Xiaotang Yu, Qingqing Zhang, Jun Zhang, Bo Song, Man Li, Lianhong Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-18 (2018)
Abstract Background Recent studies have indicated that deubiquitinating enzymes (DUBs) are related to the stem-cell pathway network and chemo-resistance in cancer. Ubiquitin-specific peptidase 37 (USP37), a novel DUB, was identified to be a potential
Externí odkaz:
https://doaj.org/article/03d336b8df2d4a039dd9606b4973d114
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 309-321 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Cullin-RING ligases (CRLs) recognize and interact with substrates for ubiquitination and degradation, and can be targeted for disease treatment when the abnormal expression of substrates involves pathologic processes. Phosphorylation, either of subst
Autor:
Han Shengbo, Wenzheng Yuan, Zhao Ning, Xiaogang Shu, Zili Zhou, Zhang Xudan, Liang Wu, Bao Haijun, Jinhuang Chen
Publikováno v:
Theranostics
Rationale: PLAGL2 (pleomorphic adenoma gene like-2), a zinc finger PLAG transcription factor, is aberrantly expressed in several malignant tumors. However, the biological roles of PLAGL2 and its underlying mechanism in gastric cancer (GC) remain uncl
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Andrew Dickson, Benjamin R. Stromberg, Christine Insinna, Matthew K. Summers, Yosup Rhee, Adrian E. Torres, Debjani Pal, Christopher J. Westlake, Mayank Singh, Amy C. Burrows
Publikováno v:
The Journal of Biological Chemistry
The deubiquitinating enzyme USP37 is known to contribute to timely onset of S phase and progression of mitosis. However, it is not clear if USP37 is required beyond S-phase entry despite expression and activity of USP37 peaking within S phase. We hav
Publikováno v:
International Journal of Medical Sciences
Background: The evolution of adriamycin (ADR) resistance in the treatment of breast cancer often leads to a poor prognosis in patients. Ubiquitin-specific peptidase 37 (USP37) has been recently identified as a modulator in regulating the stemness of
Autor:
Bo Song, Ying Lu, Xiaotang Yu, Lei Liu, Jun Mao, Lianhong Li, Jinfeng Yang, Xiaoyue Feng, Bai Li, Shujun Fan, Qingqing Zhang, Jun Zhang, Man Li, Dandan Liu, Tao Qin
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-18 (2018)
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-18 (2018)
Background Recent studies have indicated that deubiquitinating enzymes (DUBs) are related to the stem-cell pathway network and chemo-resistance in cancer. Ubiquitin-specific peptidase 37 (USP37), a novel DUB, was identified to be a potential factor a