Zobrazeno 1 - 10
of 42
pro vyhledávání: '"USP16"'
Autor:
Qingdong Wang, Hongbin Qiu
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Background Gouty arthritis is the most frequently diagnosed inflammatory arthritis worldwide. Dynamin-related protein 1 (Drp1), a regulator of mitochondrial fission, contributes to various inflammatory disorders via activating NLRP3 inflamma
Externí odkaz:
https://doaj.org/article/1b3b7699e98a4e9ea9d6ac4e38a6e378
Autor:
Valentina Serratore, Carmen Di Ruocco, Annamaria Cerantonio, Carmela De Marco, Giuseppe Viglietto
Publikováno v:
Proceedings, Vol 100, Iss 1, p 17 (2024)
Deubiquitylating enzymes are proteases that reverse the ubiquitination of proteins, an important process for maintaining normal homeostasis [...]
Externí odkaz:
https://doaj.org/article/c796594c45d146459a793cbd5d92e994
Autor:
Jianchao Ge, Wandong Yu, Junhong Li, Hangbin Ma, Pengyu Wang, Yinghao Zhou, Yang Wang, Jun Zhang, Guowei Shi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-15 (2021)
Abstract Background c-Myc, a well-established oncogene, plays an important role in the initiation and progression of various cancers, including prostate cancer. However, its mechanism in cancer cell remains largely unknown and whether there exist a d
Externí odkaz:
https://doaj.org/article/248c87517d8c46fc907833f89b5dc126
Autor:
Shou Yang, Juelu Wang, Shipeng Guo, Daochao Huang, Isabel Bestard Lorigados, Xing Nie, Dandan Lou, Yanhua Li, Mingjing Liu, Yu Kang, Weihui Zhou, Weihong Song
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Ubiquitin Specific Peptidase 16 (USP16) has been reported to contribute to somatic stem-cell defects in Down syndrome. However, how this gene being regulated is largely unknown. To study the mechanism underlying USP16 gene expression, USP16
Externí odkaz:
https://doaj.org/article/4f9de93630144f1e9d8a6b6c6c92e949
USP16 counteracts mono-ubiquitination of RPS27a and promotes maturation of the 40S ribosomal subunit
Autor:
Christian Montellese, Jasmin van den Heuvel, Caroline Ashiono, Kerstin Dörner, André Melnik, Stefanie Jonas, Ivo Zemp, Paola Picotti, Ludovic C Gillet, Ulrike Kutay
Publikováno v:
eLife, Vol 9 (2020)
Establishment of translational competence represents a decisive cytoplasmic step in the biogenesis of 40S ribosomal subunits. This involves final 18S rRNA processing and release of residual biogenesis factors, including the protein kinase RIOK1. To i
Externí odkaz:
https://doaj.org/article/3db3fbeffa8945fd95262f6e72675cdf
Akademický článek
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Autor:
Gu, Yue, Jones, Amanda E., Yang, Wei, Liu, Shanrun, Dai, Qian, Liu, Yudong, Swindle, C. Scott, Zhou, Dewang, Zhang, Zhuo, Ryan, Thomas M., Townes, Tim M., Klug, Christopher A., Chen, Dongquan, Wang, Hengbin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Jan 01. 113(1), E51-E60.
Externí odkaz:
https://www.jstor.org/stable/26467328
Autor:
Gan, J.
Publikováno v:
None
Proteins play an essential role in almost all the processes of a living organism, and post-translational modifications (PTM) can regulate their structure, location, function, and fate. Ubiquitin and ISG15 are two of the most versatile and common PTM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::26d459abcfc595e1d1e6f7ea636f1c51
http://hdl.handle.net/1887/3308336
http://hdl.handle.net/1887/3308336
Autor:
Juelu Wang, Mingjing Liu, Daochao Huang, Xing Nie, Weihong Song, Dandan Lou, Yu Kang, Yanhua Li, Shipeng Guo, Isabel Bestard Lorigados, Weihui Zhou, Shou Yang
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-12 (2019)
Molecular Brain
Molecular Brain
Ubiquitin Specific Peptidase 16 (USP16) has been reported to contribute to somatic stem-cell defects in Down syndrome. However, how this gene being regulated is largely unknown. To study the mechanism underlyingUSP16gene expression,USP16gene promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a3a81e55c1db60830e4e53984f2815
https://doaj.org/article/4f9de93630144f1e9d8a6b6c6c92e949
https://doaj.org/article/4f9de93630144f1e9d8a6b6c6c92e949
Autor:
Kim M. Summers, Iveta Gažová, David A. Hume, Rocio Rojo, Lucas Lefevre, Andreas Lengeling, Stephen J. Bush
Publikováno v:
Gažová, I, Lefevre, L, Bush, S J, Rojo, R, Hume, D A, Lengeling, A & Summers, K M 2021, ' CRISPR-Cas9 Editing of Human Histone Deubiquitinase Gene USP16 in Human Monocytic Leukemia Cell Line THP-1 ', Frontiers in Cell and Developmental Biology, vol. 9, 679544 . https://doi.org/10.3389/fcell.2021.679544
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
USP16 is a histone deubiquitinase which facilitates G2/M transition during the cell cycle, regulates DNA damage repair and contributes to inducible gene expression. We mutated the USP16 gene in a high differentiation clone of the acute monocytic leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a95eb9751edbab94851bfe319002edc
https://www.pure.ed.ac.uk/ws/files/216120720/fcell_09_679544.pdf
https://www.pure.ed.ac.uk/ws/files/216120720/fcell_09_679544.pdf