Zobrazeno 1 - 10
of 53
pro vyhledávání: '"USE1"'
Autor:
Vihalemm, Peeter
Publikováno v:
Informacijos mokslai / Information Sciences. (47):112-120
Externí odkaz:
https://www.ceeol.com/search/article-detail?id=176506
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
mBio
mBio
Vesicular trafficking is a fundamental cellular process involved in material transport in eukaryotes, but the diversity of the intracellular compartments has prevented researchers from obtaining a clear understanding of the specific functions of vesi
Autor:
Tadashi Watanabe, Jun Adachi, Kohei Hosokawa, Takayuki Murata, Yuichi Abe, Takeshi Tomonaga, Atsuko Sugimoto, Masahiro Fujimuro, Yasumasa Iwatani
Publikováno v:
J Virol
During Kaposi’s sarcoma-associated herpesvirus (KSHV) lytic replication, host cell functions, including protein expression and posttranslational modification pathways, are dysregulated by KSHV to promote virus production. Here, we attempted to iden
Autor:
Nicola Catone, Florian Stengel, Carolin Sailer, Nicola D. Roverato, Marcus Groettrup, Annette Aichem
Publikováno v:
Cell reports. 34(11)
Parkin is an E3 ubiquitin ligase belonging to the RING-between-RING family. Mutations in the Parkin-encoding gene PARK2 are associated with familial Parkinson's disease. Here, we investigate the interplay between Parkin and the inflammatory cytokine-
Autor:
Safraz Hamid, I-Mei Yu, Sophie M. Travis, Philip D. Jeffrey, Kevin DAmico, Frederick M. Hughson, Gabriel Ramirez-Arellano
Multisubunit tethering complexes (MTCs) are large (250 to >750 kDa), conserved macromolecular machines that are essential for SNARE-mediated membrane fusion in all eukaryotes. MTCs are thought to function as organizers of membrane trafficking, mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397194ea0d550ba83c391213b8e47389
Autor:
Sophie M. Travis, Safraz Hamid, Gabriel Ramirez-Arellano, Conor McMahon, Philip D. Jeffrey, Frederick M. Hughson, I-Mei Yu, Kevin DAmico
Publikováno v:
J Biol Chem
Multisubunit-tethering complexes (MTCs) are large (250 to >750 kDa), conserved macromolecular machines that are essential for soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE)–mediated membrane fusion in all eukaryotes
Autor:
Hongyuan Yang, Charles Ferguson, Jinhai Yu, Tuozhi Huang, Peng Li, Yuqi Li, Lizhen Wu, Dongyu Zhao, Dijin Xu, Ying Li, Robert G. Parton
Publikováno v:
The Journal of Cell Biology
Lipid incorporation from the ER to lipid droplets (LDs) influences LD growth and intracellular lipid homeostasis. Xu et al. identify Rab18 as an important regulator of LD dynamics: activated Rab18 binds to ER-associated proteins such as the NRZ compl
Autor:
Bo Zhao, Fengting Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2250 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Questions have been raised since the discovery of UBA6 and its significant coexistence with UBE1 in the ubiquitin−proteasome system (UPS). The facts that UBA6 has the dedicated E2 enzyme USE1 and the E1−E2 cascade can activate and transfer both u
The deubiquitylation of target proteins is mediated by deubiquitylating enzymes (DUB) such as OTUB1, which plays an important role in immune response, cell cycle progression, and DNA repair. Within these processes, OTUB1 reduces the ubiquitylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f7fed4a0db88f8630dceaa3148a929
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007028 (2018)
PLoS Pathogens
PLoS Pathogens
Positive-strand RNA viruses assemble numerous membrane-bound viral replicase complexes within large replication compartments to support their replication in infected cells. Yet the detailed mechanism of how given subcellular compartments are subverte