Zobrazeno 1 - 10
of 1 367
pro vyhledávání: '"URICASE"'
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background Uricase is a bio-drug used to reduce urate accumulation in gout disease. Thus, there is a continuous demand for screening soil samples derived from a variety of different sources in order to isolate a strain that possesses a high
Externí odkaz:
https://doaj.org/article/7d672a9643ef4fe0a66a6c9fe61e4654
Publikováno v:
Postępy Mikrobiologii, Vol 63, Iss 2, Pp 81-91 (2024)
The uricase enzyme yields allantoin, hydrogen peroxide, and carbon dioxide by catalyzing the oxidative opening of the purine ring in the urate pathway. This enzyme is important for biochemical diagnosis and reduces toxic urate accumulation during var
Externí odkaz:
https://doaj.org/article/f5d2aa5ee1f843a093f3528e039d73f5
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 13, Iss 9, Pp 3955-3959 (2024)
Background: The thyroid gland is one of the largest endocrine glands in the body, secreting thyroxine (T4) and triiodothyronine (T3). Mild hypothyroidism can have negative consequences for a variety of tissues, even though clinically the patients are
Externí odkaz:
https://doaj.org/article/699584ba0a3e4bfeafab703b32d2c113
Autor:
Yang Zhang, Xiaobo Li, Chunling Liang, Jianjia Feng, Chuyi Yu, Weichi Jiang, Keneng Cai, Wanying Chen, Wenli Cai, Feng Zeng, Qin Xu, Peng Chen, Jianming Liang
Publikováno v:
Smart Materials in Medicine, Vol 5, Iss 3, Pp 321-335 (2024)
Hyper-uric acid (UA)-induced kidney injury (HAKI) is caused by the deposition of excess blood UA into the kidneys. We confined molecules of uricase (URI), catalase (CAT), and curcumin (Cur) to a single structure (UC/Cur) while retaining their enzymat
Externí odkaz:
https://doaj.org/article/39236f1d20134487bb7ced312cb65396
Autor:
Yu-Zhong Feng, Hao Cheng, Guo-Qing Xiong, Jia-Zhen Cui, Zhi-Li Chen, Yuan-Yuan Lu, Zhi-Xin Meng, Chen Zhu, Hao-Long Dong, Xiang-Hua Xiong, Gang Liu, Qing-Yang Wang, Hui-Peng Chen
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2602 (2024)
Background: Uricase, or urate oxidase (Uox) is a key enzyme in uric acid (UA) metabolism and has been applied in clinical treatment of human hyperuricemia (HUA). However, the current clinically applied uricases, despite their potent urate-lowering ca
Externí odkaz:
https://doaj.org/article/0af7a33bad0d416f9938b4d4f3715073
Autor:
Yan Xin, Hu Wei, Zhu Yun-Guo, Liu Qing-Qing, Wang Shuai, Liu Hong-Yan, Zhu Dan, Lv Zhi-Hua, Li Lin-Hua, Yin Yi-Rui
Publikováno v:
Polish Journal of Microbiology, Vol 72, Iss 3, Pp 277-283 (2023)
Uricase (or Urate oxidase), a key enzyme involved in purine metabolism, is commonly used in treating conditions such as gout, hyperuricemia, and tumor lysis syndrome. In this study, a uricase-producing strain (named CSAJ-16) was isolated from the soi
Externí odkaz:
https://doaj.org/article/6da47f4159e144878ec550ed052f3729
Autor:
Lin Wang, Jianping Ye
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 1, Pp 433-435 (2024)
Externí odkaz:
https://doaj.org/article/ba495eb18d64412ab50390cf19041e1d
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Publikováno v:
Chemosensors, Vol 12, Iss 6, p 98 (2024)
Simple and reliable electrochemical sensors are highly demanded in medicine and pharmacy for the fast determination of metabolites and biomarkers of diseases. In this work, a flow-through biosensor system was developed on the base of a screen-printed
Externí odkaz:
https://doaj.org/article/82972f8f07154643881da6d0be7ca31b