Zobrazeno 1 - 10
of 60
pro vyhledávání: '"ULF STRAUß"'
Autor:
Egor Byvaltcev, Mahraz Behbood, Jan-Hendrik Schleimer, Thomas Gensch, Alexey Semyanov, Susanne Schreiber, Ulf Strauss
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112934- (2023)
Summary: Extracellular potassium [K+]o elevation during synaptic activity retrogradely modifies presynaptic release and astrocytic uptake of glutamate. Hence, local K+ clearance and replenishment mechanisms are crucial regulators of glutamatergic tra
Externí odkaz:
https://doaj.org/article/28fd3a5c95294eaaba302a11f6966b4c
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Interferon-γ (IFN-γ), a cytokine with neuromodulatory properties, has been shown to enhance inhibitory transmission. Because early inhibitory neurotransmission sculpts functional neuronal circuits, its developmental alteration may have grave conseq
Externí odkaz:
https://doaj.org/article/a4a2c1d816e44d32ab462420c7cbd4cc
Autor:
Gabriel M. S. Janach, Olivia Reetz, Noah Döhne, Konstantin Stadler, Sabine Grosser, Egor Byvaltcev, Anja U. Bräuer, Ulf Strauss
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Interferon-γ (IFN-γ, a type II IFN) is present in the central nervous system (CNS) under various conditions. Evidence is emerging that, in addition to its immunological role, IFN-γ modulates neuronal morphology, function, and d
Externí odkaz:
https://doaj.org/article/f2bc1f3ce63b4b888259b67d1e61434f
Autor:
Sami Zaqout, Kathrin Blaesius, Yuan-Ju Wu, Stefanie Ott, Nadine Kraemer, Lena-Luise Becker, Marta Rosário, Christian Rosenmund, Ulf Strauss, Angela M. Kaindl
Publikováno v:
Neurobiology of Disease, Vol 129, Iss , Pp 130-143 (2019)
Congenital microcephaly is highly associated with intellectual disability. Features of autosomal recessive primary microcephaly subtype 3 (MCPH3) also include hyperactivity and seizures. The disease is caused by biallelic mutations in the Cyclin-depe
Externí odkaz:
https://doaj.org/article/d93807af9cd24d4c88905df5b032fea0
Publikováno v:
Cellular Physiology and Biochemistry, Vol 38, Iss 6, Pp 2079-2093 (2016)
Background/Aims: Cationic currents (Ih) through the fast activating and relatively cAMP insensitive subtype of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, HCN1, are limited by cytosolic factors in mammalian cells. This cytosol
Externí odkaz:
https://doaj.org/article/6ff1fb4426aa40569f4d0cb3d2bf58b3
Autor:
Olivia Reetz, Ulf Strauss
Publikováno v:
Cellular Physiology and Biochemistry, Vol 31, Iss 4-5, Pp 532-541 (2013)
Background/Aims: Hyperpolarization activated cyclic nucleotide gated 1 (HCN1) channels determine neuronal excitability in several brain regions. In contrast to HCN2 and HCN4, HCN1 is less sensitive to cAMP and the number of other known modulators is
Externí odkaz:
https://doaj.org/article/a1c8f86a69e4423696f6788d42003d27
Autor:
Karl Nowak, Eilhard Mix, Jan Gimsa, Ulf Strauss, Kiran Kumar Sriperumbudur, Reiner Benecke, Ulrike Gimsa
Publikováno v:
Parkinson's Disease, Vol 2011 (2011)
Deep brain stimulation (DBS) has become a treatment for a growing number of neurological and psychiatric disorders, especially for therapy-refractory Parkinson's disease (PD). However, not all of the symptoms of PD are sufficiently improved in all pa
Externí odkaz:
https://doaj.org/article/371a5ebfa5cf4b0b91ac196f77a4319e
Publikováno v:
Brain, Behavior, and Immunity. 101:153-164
Autor:
Gabriel M S, Janach, Maximilian, Böhm, Noah, Döhne, Ha-Rang, Kim, Marta, Rosário, Ulf, Strauss
Publikováno v:
Brain, behavior, and immunity. 101
Interferon-γ (IFN-γ), an important mediator of the antiviral immune response, can also act as a neuromodulator. CNS IFN-γ levels rise acutely in response to infection and therapeutically applied IFN-γ provokes CNS related side effects. Moreover,
Publikováno v:
SSRN Electronic Journal.
Accumulation of extracellular potassium [K+]o during neuronal activity challenges neuronal function and, therefore, requires a tight control. Based on electrophysiological recordings of astrocytic /Kir as a sensor of [K+]o, we demonstrate that KCC2 c