Zobrazeno 1 - 10
of 16
pro vyhledávání: '"UK Primary Sjögren's Syndrome Registry"'
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/38d950a26aca41828a73087f5c462f45
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The genetic architecture underlying Sjögren’s syndrome is not fully understood. Here, the authors perform a genome-wide association study to identify 10 new genetic risk regions, implicating genes involved in immune and salivary gland function.
Externí odkaz:
https://doaj.org/article/ee17c34d06624822ae2f0ffc7f740171
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/75a032d749534f8d9af7665484459379
Autor:
Katherine James, Shereen Al-Ali, Jessica Tarn, Simon J Cockell, Colin S Gillespie, Victoria Hindmarsh, James Locke, Sheryl Mitchell, Dennis Lendrem, Simon Bowman, Elizabeth Price, Colin T Pease, Paul Emery, Peter Lanyon, John A Hunter, Monica Gupta, Michele Bombardieri, Nurhan Sutcliffe, Costantino Pitzalis, John McLaren, Annie Cooper, Marian Regan, Ian Giles, David Isenberg, Vadivelu Saravanan, David Coady, Bhaskar Dasgupta, Neil McHugh, Steven Young-Min, Robert Moots, Nagui Gendi, Mohammed Akil, Bridget Griffiths, UK Primary Sjögren’s Syndrome registry, Anil Wipat, Julia Newton, David E Jones, John Isaacs, Jennifer Hallinan, Wan-Fai Ng
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143970 (2015)
BackgroundFatigue is a debilitating condition with a significant impact on patients' quality of life. Fatigue is frequently reported by patients suffering from primary Sjögren's Syndrome (pSS), a chronic autoimmune condition characterised by dryness
Externí odkaz:
https://doaj.org/article/333a2390dabb4de4ba837411881664ff
Autor:
Khatri, Bhuwan, Tessneer, Kandice L, Rasmussen, Astrid, Aghakhanian, Farhang, Reksten, Tove Ragna, Adler, Adam, Alevizos, Ilias, Anaya, Juan-Manuel, Aqrawi, Lara A, Baecklund, Eva, Brun, Johan G, Bucher, Sara Magnusson, Eloranta, Maija-Leena, Engelke, Fiona, Forsblad-d'Elia, Helena, Glenn, Stuart B, Hammenfors, Daniel, Imgenberg-Kreuz, Juliana, Jensen, Janicke Liaaen, Johnsen, Svein Joar Auglænd, Jonsson, Malin V, Kvarnström, Marika, Kelly, Jennifer A, Li, He, Mandl, Thomas, Martín, Javier, Nocturne, Gaétane, Norheim, Katrine Brække, Palm, Øyvind, Skarstein, Kathrine, Stolarczyk, Anna M, Taylor, Kimberly E, Teruel, Maria, Theander, Elke, Venuturupalli, Swamy, Wallace, Daniel J, Grundahl, Kiely M, Hefner, Kimberly S, Radfar, Lida, Lewis, David M, Stone, Donald U, Kaufman, C Erick, Brennan, Michael T, Guthridge, Joel M, James, Judith A, Scofield, R Hal, Gaffney, Patrick M, Criswell, Lindsey A, Jonsson, Roland, Eriksson, Per, Bowman, Simon J, Omdal, Roald, Rönnblom, Lars, Warner, Blake, Rischmueller, Maureen, Witte, Torsten, Farris, A Darise, Mariette, Xavier, Alarcon-Riquelme, Marta E, PRECISESADS Clinical Consortium, Shiboski, Caroline H, Sjögren’s International Collaborative Clinical Alliance (SICCA), Wahren-Herlenius, Marie, Ng, Wan-Fai, UK Primary Sjögren’s Syndrome Registry, Sivils, Kathy L, Adrianto, Indra, Nordmark, Gunnel, Lessard, Christopher J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe158fc3effb3736b17c17fe80fc4404
https://www.nature.com/articles/s41467-022-34311-8.pdf
https://www.nature.com/articles/s41467-022-34311-8.pdf
Autor:
He Li, Tove Ragna Reksten, John A Ice, Jennifer A Kelly, Indra Adrianto, Astrid Rasmussen, Shaofeng Wang, Bo He, Kiely M Grundahl, Stuart B Glenn, Corinne Miceli-Richard, Simon Bowman, Sue Lester, Per Eriksson, Maija-Leena Eloranta, Johan G Brun, Lasse G Gøransson, Erna Harboe, Joel M Guthridge, Kenneth M Kaufman, Marika Kvarnström, Deborah S Cunninghame Graham, Ketan Patel, Adam J Adler, A Darise Farris, Michael T Brennan, James Chodosh, Rajaram Gopalakrishnan, Michael H Weisman, Swamy Venuturupalli, Daniel J Wallace, Kimberly S Hefner, Glen D Houston, Andrew J W Huang, Pamela J Hughes, David M Lewis, Lida Radfar, Evan S Vista, Contessa E Edgar, Michael D Rohrer, Donald U Stone, Timothy J Vyse, John B Harley, Patrick M Gaffney, Judith A James, Sean Turner, Ilias Alevizos, Juan-Manuel Anaya, Nelson L Rhodus, Barbara M Segal, Courtney G Montgomery, R Hal Scofield, Susan Kovats, Xavier Mariette, Lars Rönnblom, Torsten Witte, Maureen Rischmueller, Marie Wahren-Herlenius, Roald Omdal, Roland Jonsson, Wan-Fai Ng, for UK Primary Sjögren's Syndrome Registry, Gunnel Nordmark, Christopher J Lessard, Kathy L Sivils
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006820 (2017)
Sjögren's syndrome (SS) is a common, autoimmune exocrinopathy distinguished by keratoconjunctivitis sicca and xerostomia. Patients frequently develop serious complications including lymphoma, pulmonary dysfunction, neuropathy, vasculitis, and debili
Externí odkaz:
https://doaj.org/article/de75960e36dc428c8be5c64c20d692ba
Autor:
Khatri, Bhuwan, Tessneer, Kandice L, Rasmussen, Astrid, Aghakhanian, Farhang, Reksten, Tove Ragna, Adler, Adam, Alevizos, Ilias, Anaya, Juan-Manuel, Aqrawi, Lara A, Baecklund, Eva, Brun, Johan G, Bucher, Sara Magnusson, Eloranta, Maija-Leena, Engelke, Fiona, Forsblad-d'Elia, Helena, Glenn, Stuart B, Hammenfors, Daniel, Imgenberg-Kreuz, Juliana, Jensen, Janicke Liaaen, Johnsen, Svein Joar Auglænd, Jonsson, Malin V, Kvarnström, Marika, Kelly, Jennifer A, Li, He, Mandl, Thomas, Martín, Javier, Nocturne, Gaétane, Norheim, Katrine Brække, Palm, Øyvind, Skarstein, Kathrine, Stolarczyk, Anna M, Taylor, Kimberly E, Teruel, Maria, Theander, Elke, Venuturupalli, Swamy, Wallace, Daniel J, Grundahl, Kiely M, Hefner, Kimberly S, Radfar, Lida, Lewis, David M, Stone, Donald U, Kaufman, C Erick, Brennan, Michael T, Guthridge, Joel M, James, Judith A, Scofield, R Hal, Gaffney, Patrick M, Criswell, Lindsey A, Jonsson, Roland, Eriksson, Per, Bowman, Simon J, Omdal, Roald, Rönnblom, Lars, Warner, Blake, Rischmueller, Maureen, Witte, Torsten, Farris, A Darise, Mariette, Xavier, Alarcon-Riquelme, Marta E, PRECISESADS Clinical Consortium, Shiboski, Caroline H, Sjögren’s International Collaborative Clinical Alliance (SICCA), Wahren-Herlenius, Marie, Ng, Wan-Fai, UK Primary Sjögren’s Syndrome Registry, Sivils, Kathy L, Adrianto, Indra, Nordmark, Gunnel, Lessard, Christopher J
Publikováno v:
Nature Communications
Sjögren’s disease is a complex autoimmune disease with twelve established susceptibility loci. This genome-wide association study (GWAS) identifies ten novel genome-wide significant (GWS) regions in Sjögren’s cases of European ancestry: CD247,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868876cabf7558d9450062b692898174
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-482091
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-482091
Autor:
Dennis Lendrem, James Locke, Ben Hargreaves, Wan-Fai Ng, Jessica Tarn, Simon J. Bowman, Victoria Macrae, Emmanuella Traianos, UK primary Sjögren’s syndrome registry
Publikováno v:
Rheumatology International
Primary Sjögren’s syndrome (pSS) is an autoimmune disease characterised by an increased risk for non-Hodgkin lymphoma (NHL) development. Ectopic germinal centre (GC) in the salivary gland is associated with increased NHL risk in pSS, and the chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bc743ec3d71bc21945efd7046f2532
https://pubmed.ncbi.nlm.nih.gov/32047959
https://pubmed.ncbi.nlm.nih.gov/32047959
Autor:
Tarn, JR, Howard-Tripp, N, Lendrem, DW, Mariette, X, Saraux, A, Devauchelle-Pensec, V, Seror, R, Skelton, AJ, James, K, McMeekin, P, Al-Ali, S, Hackett, KL, Lendrem, BC, Hargreaves, B, Casement, J, Mitchell, S, Bowman, SJ, Price, E, Pease, CT, Emery, P, Lanyon, P, Hunter, J, Gupta, M, Bombardieri, M, Sutcliffe, N, Pitzalis, C, McLaren, J, Cooper, A, Regan, M, Giles, I, Isenberg, D, Saravanan, V, Coady, D, Dasgupta, B, McHugh, N, Young-Min, S, Moots, R, Gendi, N, Akil, M, Griffiths, B, Johnsen, SJA, Norheim, KB, Omdal, R, Stocken, D, Everett, C, Fernandez, C, Isaacs, JD, Gottenberg, J-E, Ng, W-F, French ASSESS cohort, UK Primary Sjögren's Syndrome Registry
Background Heterogeneity is a major obstacle to developing effective treatments for patients with primary Sjögren's syndrome. We aimed to develop a robust method for stratification, exploiting heterogeneity in patient-reported symptoms, and to relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::97af6517ec3a0615b03cf0791fda16ea
Autor:
Wan-Fai Ng, Benjamin A Fisher, Stephen Harding, Chimwemwe Chipeta, Jennifer Hallinan, UK primary Sjögren’s syndrome registry, Simon Cockell, Simon J Bowman, Katherine James, Colin S. Gillespie, Francesca Barone, Antony R. Parker
Publikováno v:
Rheumatology (Oxford, England)
Objectives B-cell activating factor (BAFF), β-2 microglobulin (β2M) and serum free light chains (FLCs) are elevated in primary SS (pSS) and associated with disease activity. We aimed to investigate their association with the individual disease acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0724f2f4c184ca118f27fbf9c788f205
https://pubmed.ncbi.nlm.nih.gov/29608774
https://pubmed.ncbi.nlm.nih.gov/29608774