Zobrazeno 1 - 10
of 1 013
pro vyhledávání: '"UHRF1"'
Autor:
Junsheng Chen, Da Wang, Guanhua Wu, Fei Xiong, Wenzheng Liu, Qi Wang, Yiyang Kuai, Wenhua Huang, Yongqiang Qi, Bing Wang, Yongjun Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Cholangiocarcinoma (CCA) is a highly malignant tumor characterized by a lack of effective targeted therapeutic strategies. The protein UHRF1 plays a pivotal role in the preservation of DNA methylation and works synergistically wit
Externí odkaz:
https://doaj.org/article/ec3703bda7144579857e33fa9392d7ad
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract UHRF1 as a member of RING-finger type E3 ubiquitin ligases family, is an epigenetic regulator with five structural domains. It has been involved in the regulation of a series of biological functions, such as DNA replication, DNA methylation,
Externí odkaz:
https://doaj.org/article/50048beb41b84f47a22de5be4990d796
Publikováno v:
Mobile DNA, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Background Repeat elements (REs) play important roles for cell function in health and disease. However, RE enrichment analysis in short-read high-throughput sequencing (HTS) data, such as ChIP-seq, is a challenging task. Results Here, we pre
Externí odkaz:
https://doaj.org/article/6bbedbe0055f4eb0b0b726bf50b4a139
Autor:
Jiyan Su, Xiaojie Lin, Dan Li, Chunmin Yang, Shumei Lv, Xiaohong Chen, Xiujuan Yang, Botao Pan, Rui Xu, Liping Ren, Yanfang Zhang, Yizhen Xie, Qianjun Chen, Chenglai Xia
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTEmerging evidence has revealed the novel role of gut microbiota in the development of cancer. The characteristics of function and composition in the gut microbiota of patients with breast cancer patients has been reported, however the detaile
Externí odkaz:
https://doaj.org/article/0b8122d2e20846538e84dca6da72e50e
Autor:
Zhiyi Xue, Yan Zhang, Ruiqi Zhao, Xiaofei Liu, Konrad Grützmann, Barbara Klink, Xun Zhang, Shuai Wang, Wenbo Zhao, Yanfei Sun, Mingzhi Han, Xu Wang, Yaotian Hu, Xuemeng Liu, Ning Yang, Chen Qiu, Wenjie Li, Bin Huang, Xingang Li, Rolf Bjerkvig, Jian Wang, Wenjing Zhou
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Extensive local invasion of glioblastoma (GBM) cells within the central nervous system (CNS) is one factor that severely limits current treatments. The aim of this study was to uncover genes involved in the invasion process, which
Externí odkaz:
https://doaj.org/article/3709a13eb6e6463d87738a92665b2ac2
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 50, Iss 11, Pp 1075-1083 (2023)
Objective To explore the relationship of UHRF1 with the clinicopathological characteristics of colorectal cancer (CRC) patients, as well as the effects of lentivirus transfection overexpression and knockdown of UHRF1 on the proliferation, invasion, a
Externí odkaz:
https://doaj.org/article/226d0f2440fc4c97ab6810c3407be588
Autor:
Ahhyun Kim, Claudia A. Benavente
Publikováno v:
Epigenomes, Vol 8, Iss 3, p 26 (2024)
Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) is an essential protein involved in the maintenance of repressive epigenetic marks, ensuring epigenetic stability and fidelity. As an epigenetic regulator, UHRF1 comprises several functional d
Externí odkaz:
https://doaj.org/article/732cf8512ce34b9884ec63803a2a900c
Autor:
RE Irwin, C Scullion, SJ Thursby, M Sun, A Thakur, L Hilman, B Callaghan, PD Thompson, DJ McKenna, SB Rothbart, Guoliang Xu, CP Walsh
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
While epigenetic mechanisms such as DNA methylation and histone modification are known to be important for gene suppression, relatively little is still understood about the interplay between these systems. The UHRF1 protein can interact with both DNA
Externí odkaz:
https://doaj.org/article/8898c91f9e5e4799bdbc4e33954c6e9b
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Akademický článek
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