Zobrazeno 1 - 10
of 278
pro vyhledávání: '"UFMylation"'
Autor:
Zhengyan Liang, Rongxuan Ning, Zhaoxiang Wang, Xia Kong, Yubin Yan, Yafei Cai, Zhiwei He, Xin‐guang Liu, Yongkang Zou, Junzhi Zhou
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Post‐translational modification is a rite of passage for cellular functional proteins and ultimately regulate almost all aspects of life. Ubiquitin‐fold modifier 1 (UFM1) system represents a newly identified ubiquitin‐like modification
Externí odkaz:
https://doaj.org/article/29d30e569b3a458cbb6d3114f5c62937
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Protein post-translational modifications (PTMs) represent a crucial aspect of cellular regulation, occurring after protein synthesis from mRNA. These modifications, which include phosphorylation, ubiquitination, acetylation, methylation, glycosylatio
Externí odkaz:
https://doaj.org/article/344a445268bf4b318920ff040b780f7d
Autor:
Jie Ran, Guizhi Guo, Sai Zhang, Yufei Zhang, Liang Zhang, Dengwen Li, Shian Wu, Yusheng Cong, Xiaohong Wang, Songbo Xie, Huijie Zhao, Hongbin Liu, Guangshuo Ou, Xueliang Zhu, Jun Zhou, Min Liu
Publikováno v:
Advanced Science, Vol 11, Iss 25, Pp n/a-n/a (2024)
Abstract The photoreceptor cilium is vital for maintaining the structure and function of the retina. However, the molecular mechanisms underlying the photoreceptor cilium integrity and retinal homeostasis are largely unknown. Herein, it is shown that
Externí odkaz:
https://doaj.org/article/b77ae1bf12574273bab60b2a73cdc525
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract UFMylation is a ubiquitination-like modification that is related to endoplasmic reticulum stress and unfolded protein response. A recent study reported that Ufl1, a key enzyme of UFMylation, protects against heart failure, indicating that UF
Externí odkaz:
https://doaj.org/article/c9e91a0866c24e56ba008cabd1d57bc3
Autor:
Michael R. McAllaster, Jaya Bhushan, Dale R. Balce, Anthony Orvedahl, Arnold Park, Seungmin Hwang, Meagan E. Sullender, L. David Sibley, Herbert W. Virgin
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTGenes required for the lysosomal degradation pathway of autophagy play key roles in topologically distinct and physiologically important cellular processes. Some functions of ATG genes are independent of their role in degradative autophagy. O
Externí odkaz:
https://doaj.org/article/ee73c35548d94fc394c27a7238cc9bbd
Autor:
Xueyang Pan, Albert N Alvarez, Mengqi Ma, Shenzhao Lu, Michael W Crawford, Lauren C Briere, Oguz Kanca, Shinya Yamamoto, David A Sweetser, Jenny L Wilson, Ruth J Napier, Jonathan N Pruneda, Hugo J Bellen
Publikováno v:
eLife, Vol 12 (2023)
Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and endoplasmic reticulum stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive dis
Externí odkaz:
https://doaj.org/article/628d985a60454271b521505c531678b8
Akademický článek
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Akademický článek
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Publikováno v:
Cells, Vol 12, Iss 21, p 2543 (2023)
Ubiquitin-fold modifier 1 (UFM1) is a newly identified ubiquitin-like protein that has been conserved during the evolution of multicellular organisms. In a similar manner to ubiquitin, UFM1 can become covalently linked to the lysine residue of a subs
Externí odkaz:
https://doaj.org/article/7e2429a23b66431dbeee49b801c4d4bb
Autor:
Qiang Jiang, Yongsheng Wang, Minghui Xiang, Jiamin Hua, Tianci Zhou, Fanghui Chen, Xiaoyang Lv, Jinming Huang, Yafei Cai
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The UFM1 conjugation system(UFMylation)is a novel type of ubiquitin-like system that plays an indispensable role in maintaining cell homeostasis under various cellular stress. Similar to ubiquitination, UFMylation consists of a three-step enzymatic r
Externí odkaz:
https://doaj.org/article/9a75f09e05a04ad7977c643718a9a549