Prothrombotic disturbances of hemostasis of patients with severe COVID-19

Autor: Thomas Lecompte, Geoffrey Horlait, Hugues Jacqmin, Silvy Laporte, A. Dive, Isabelle Michaux, Jean-Michel Dogné, Sophie Testa, Céline Chapelle, Michael Hardy, François Mullier, Pierre Bulpa, Jonathan Douxfils, Marion Bareille, Sarah Lessire

Publikováno v: Thrombosis research, Vol. 197, p. 20-23 (2021)
Hardy, M, Michaux, I, Lessire, S, Douxfils, J, Dogné, J-M, Bareille, M, Horlait, G, Bulpa, P, Chapelle, C, Laporte, S, Testa, S, Jacqmin, H, Lecompte, T, Dive, A & Mullier, F 2021, ' Prothrombotic disturbances of hemostasis of patients with severe COVID-19 : A prospective longitudinal observational study ', Thrombosis Research, vol. 197, pp. 20-23 . https://doi.org/10.1016/j.thromres.2020.10.025
Thrombosis research, Vol. 197, p. 20-23 (2020)
Thrombosis Research

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815cd97b0c1a0871265815f05f7dee6c
https://doi.org/10.1016/j.thromres.2020.10.025

Asymptomatic deep vein thrombosis in critically ill COVID-19 patients despite therapeutic levels of anti-Xa activity

Autor: Hugo Rodríguez-Zanella, Claudia Lerma, Sergio Mora-Canela, Victor Manuel Anguiano-Álvarez, Raúl Izaguirre-Ávila, Gustavo Rojas-Velasco, Flavio A Grimaldo-Gómez, Samuel Ramirez-Marroquin, Ángel Ramos-Enríquez, Adriana Torres-Machorro, Edgar García-Cruz, Evelyn Cortina-de la Rosa

Publikováno v: Thrombosis Research

Highlights • Clinical signs are not useful for detecting DVT in critically ill COVID-19 patients • DVT occurs despite full dose anticoagulation in critically ill COVID-19 patients • Severe COVID-19 patients present a high prevalence of bilatera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be3697ec41e74ec3efa4ab7bdb8aba2
http://europepmc.org/articles/PMC7462642

Fibrinolytics as an ARDS Salvage Option

Autor: Andrew P, Cap

Publikováno v: Chest

Background Pulmonary vascular microthrombi are a proposed mechanism of COVID19 respiratory failure. We hypothesized that early administration of tissue-plasminogen activator(tPA) followed by therapeutic heparin would improve pulmonary function in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499c3a7c368a3ca1e8c0249cca23364d
http://europepmc.org/articles/PMC8767759

Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy

Autor: Andrew S. Herbert, Jawed Fareed, John M. Dye, Samantha E. Zak, Dawid Maciorowski, Yash Gupta, Prakasha Kempaiah, Chandrashekhar Vishwanath Kulkarni, Ravi Durvasula

Publikováno v: International Journal of Biological Macromolecules

The world is currently facing a novel coronavirus (SARS-CoV-2) pandemic. The greatest threat that is disrupting the normal functioning of society is the exceptionally high species independent transmission. Drug repurposing is understood to be the bes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea065f947773bf8e5c62267b4dd2916

Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19:JACC State-of-the-Art Review

Autor: Azita H, Talasaz, Parham, Sadeghipour, Hessam, Kakavand, Maryam, Aghakouchakzadeh, Elaheh, Kordzadeh-Kermani, Benjamin W, Van Tassell, Azin, Gheymati, Hamid, Ariannejad, Seyed Hossein, Hosseini, Sepehr, Jamalkhani, Michelle, Sholzberg, Manuel, Monreal, David, Jimenez, Gregory, Piazza, Sahil A, Parikh, Ajay J, Kirtane, John W, Eikelboom, Jean M, Connors, Beverley J, Hunt, Stavros V, Konstantinides, Mary, Cushman, Jeffrey I, Weitz, Gregg W, Stone, Harlan M, Krumholz, Gregory Y H, Lip, Samuel Z, Goldhaber, Behnood, Bikdeli

Publikováno v: Talasaz, A H, Sadeghipour, P, Kakavand, H, Aghakouchakzadeh, M, Kordzadeh-Kermani, E, Van Tassell, B W, Gheymati, A, Ariannejad, H, Hosseini, S H, Jamalkhani, S, Sholzberg, M, Monreal, M, Jimenez, D, Piazza, G, Parikh, S A, Kirtane, A J, Eikelboom, J W, Connors, J M, Hunt, B J, Konstantinides, S V, Cushman, M, Weitz, J I, Stone, G W, Krumholz, H M, Lip, G Y H, Goldhaber, S Z & Bikdeli, B 2021, ' Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19 : JACC State-of-the-Art Review ', Journal of the American College of Cardiology, vol. 77, no. 15, pp. 1903-1921 . https://doi.org/10.1016/j.jacc.2021.02.035
Journal of the American College of Cardiology

Endothelial injury and microvascular/macrovascular thrombosis are common pathophysiological features of coronavirus disease-2019 (COVID-19). However, the optimal thromboprophylactic regimens remain unknown across the spectrum of illness severity of C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9cfd53875c4beb17c4b2acdd6680cbaf
https://vbn.aau.dk/da/publications/4fc75eda-f137-462d-9d70-f4b8fb2a0e43