Zobrazeno 1 - 10
of 106
pro vyhledávání: '"UDCA - Ursodeoxycholic acid"'
Publikováno v:
Journal of Clinical & Translational Endocrinology
Journal of Clinical & Translational Endocrinology, Vol 27, Iss, Pp 100283-(2022)
Journal of Clinical & Translational Endocrinology, Vol 27, Iss, Pp 100283-(2022)
Highlights • Development of CFLD adds significant morbidity and mortality to those with CF. • CFLD is associated with an increased prevalence of endocrinopathies. • Current treatment options for CFLD remain limited. • Early recognition and tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50076327343e69ce43546cd506b189c
http://europepmc.org/articles/PMC8724940
http://europepmc.org/articles/PMC8724940
Autor:
Petia Shipkova, Giridhar S. Tirucherai, Arun J. Sanyal, Diane E. Shevell, Benjamin E. Decato, Colleen A. McNaney, Yi Luo, Edgar D. Charles, Abraham Apfel
Publikováno v:
JHEP Reports
Background & Aims Increased serum bile acids (BAs) have been observed in patients with non-alcoholic steatohepatitis (NASH). Pegbelfermin (PGBF), a polyethylene glycol-modified (PEGylated) analogue of human fibroblast growth factor 21 (FGF21), signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c523b47362c4cc87193b195c73edfb6d
https://pubmed.ncbi.nlm.nih.gov/34977519
https://pubmed.ncbi.nlm.nih.gov/34977519
Autor:
Stefan Zeuzem, Johannes Vermehren, Jeannette Arncken, Julia Dietz, Nils Wetzstein, Jessica Seessle, Christian M. Lange, Antonia Mondorf, Christiana Graf, Jörn M. Schattenberg, Tobias Böttler, Julia Lang-Meli, Anita Pathil, Katharina Willuweit, Gernot Rohde
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 6, Pp 100360-(2021)
JHEP Reports, Vol 3, Iss 6, Pp 100360-(2021)
Background & Aims Clinical manifestation of hepatic involvement in sarcoidosis can vary from asymptomatic disease to severe complications such as cirrhosis and portal hypertension. However, data on hepatic sarcoidosis are limited, and evidence-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f42316cbd7d29cc2776989b0c7e882
https://pubmed.ncbi.nlm.nih.gov/34765958
https://pubmed.ncbi.nlm.nih.gov/34765958
Autor:
Spatz, Madeleine, Ciocan, Dragos, Merlen, Gregory, Rainteau, Dominique, Humbert, Lydie, Gomes-Rochette, Neuza, Hugot, Cindy, Trainel, Nicolas, Mercier-Nomé, Françoise, Domenichini, Séverine, Puchois, Virginie, Wrzosek, Laura, Ferrere, Gladys, Tordjmann, Thierry, Perlemuter, Gabriel, Cassard, Anne-Marie
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100230-(2021)
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100230. ⟨10.1016/j.jhepr.2021.100230⟩
JHEP Reports
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100230. ⟨10.1016/j.jhepr.2021.100230⟩
JHEP Reports
Background & Aims Bile-acid metabolism and the intestinal microbiota are impaired in alcohol-related liver disease. Activation of the bile-acid receptor TGR5 (or GPBAR1) controls both biliary homeostasis and inflammatory processes. We examined the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ae520b76500b6b211e8c427c2e781d78
http://www.sciencedirect.com/science/article/pii/S2589555921000069
http://www.sciencedirect.com/science/article/pii/S2589555921000069
Autor:
Grzych, Guillaume, Chavez-Talavera, Oscar, Descat, Amandine, Thuillier, Dorothee, Verrijken, An, Kouach, Mostafa, Legry, Vanessa, Verkindt, Helene, Raverdy, Violeta, Legendre, Benjamin, Caiazzo, Robert, Van Gaal, Luc, Goossens, Jean-Francois, Paumelle, Rejane, Francque, Sven, Pattou, Francois, Haas, Joel T., Tailleux, Anne, Staels, Bart
Publikováno v:
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100222-(2021)
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100222-(2021)
Background & Aims Plasma bile acids (BAs) have been extensively studied as pathophysiological actors in non-alcoholic steatohepatitis (NASH). However, results from clinical studies are often complicated by the association of NASH with type 2 diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::74e69ecb4a62b415846d1ee012802a9c
https://www.hal.inserm.fr/inserm-03173334/document
https://www.hal.inserm.fr/inserm-03173334/document
Autor:
Hsiao D. Lieu, Gideon M. Hirschfield, Arun J. Sanyal, Stephen A. Harrison, Lei Ling, Ulrich Beuers, Alex M. DePaoli
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100255-(2021)
JHEP Reports, 3(3):100255. Elsevier
JHEP Reports, Vol 3, Iss 3, Pp 100255-(2021)
JHEP Reports, 3(3):100255. Elsevier
Summary Background & Aims Higher serum bile acid levels are associated with an increased risk of cirrhosis and liver-related morbidity and mortality. Herein, we report secondary analyses of aldafermin, an engineered analogue of the gut hormone fibrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7001e197981d0d939e7dc5af50542f
https://pubmed.ncbi.nlm.nih.gov/33898959
https://pubmed.ncbi.nlm.nih.gov/33898959
Autor:
Annarosa Floreani, Maria Guido, Giorgia Corrà, Francesco Paolo Russo, Vincenza Guzzardo, Samantha Sarcognato, Sara De Martin, Nora Cazzagon
Publikováno v:
JHEP Reports, Vol 3, Iss 3, Pp 100286-(2021)
JHEP Reports
JHEP Reports
Background & Aims Primary sclerosing cholangitis (PSC) is a rare cholangiopathy of unknown aetiopathogenesis. The aim of this study was to evaluate cellular senescence (CS) marker expression in cholangiocytes of patients with PSC and their correlatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fdc9d7ab3307244183b4e336900ac8
https://hdl.handle.net/11577/3390578
https://hdl.handle.net/11577/3390578
Autor:
Bidault-Jourdainne, Valeska, Merlen, Grégory, Glénisson, Mathilde, Doignon, Isabelle, Garcin, Isabelle, Péan, Noémie, Boisgard, Raphaël, Ursic-Bedoya, José, Serino, Matteo, Ullmer, Christoph, Humbert, Lydie, Abdelrafee, Ahmed, Golse, Nicolas, Vibert, Eric, Duclos-Vallée, Jean-Charles, Rainteau, Dominique, Tordjmann, Thierry
Publikováno v:
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100214. ⟨10.1016/j.jhepr.2020.100214⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100214. ⟨10.1016/j.jhepr.2020.100214⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100214-(2021)
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100214. ⟨10.1016/j.jhepr.2020.100214⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100214. ⟨10.1016/j.jhepr.2020.100214⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100214-(2021)
Background & Aims As the composition of the bile acid (BA) pool has a major impact on liver pathophysiology, we studied its regulation by the BA receptor Takeda G protein coupled receptor (TGR5), which promotes hepatoprotection against BA overload. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bd93ad251fbdc56587d850b8c657ea9c
https://hal.sorbonne-universite.fr/hal-03148612
https://hal.sorbonne-universite.fr/hal-03148612
Autor:
Mette Vesterhus, Kristine Wiencke, Anders Batman Mjelle, Odd Helge Gilja, Lasse Melvaer Giil, William Rosenberg, Tom H. Karlsen, Ida Torunn Bjørk, Trine Folseraas, Guri Fossdal
Publikováno v:
JHEP Reports, Vol 3, Iss 5, Pp 100328-(2021)
JHEP Reports
JHEP Reports
Background & Aims Primary sclerosing cholangitis (PSC) is a progressive liver disease characterised by fluctuating liver biochemistries and highly variable disease progression. The Enhanced Liver Fibrosis (ELF®) test and liver stiffness measurements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89e33046c233b325416c282fa55992c
http://hdl.handle.net/10852/92769
http://hdl.handle.net/10852/92769
Autor:
Bertrand Condat, Yves Chrétien, Magalie Picon-Coste, Olivier Chazouillères, David Zanditenas, Lionel Arrivé, Chantal Housset, Pascal Potier, Karima Ben Belkacem, Farid Gaouar, Catherine Dong, Marie-Pierre Hauuy, Raoul Poupon, Anware Maftouh, Véronique Barbu, Christophe Corpechot, Béatrice Noblinski
Publikováno v:
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100201. ⟨10.1016/j.jhepr.2020.100201⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100201. ⟨10.1016/j.jhepr.2020.100201⟩
JHEP Reports, Vol 3, Iss 2, Pp 100201-(2021)
JHEP Reports
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100201. ⟨10.1016/j.jhepr.2020.100201⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100201. ⟨10.1016/j.jhepr.2020.100201⟩
JHEP Reports, Vol 3, Iss 2, Pp 100201-(2021)
JHEP Reports
Background & Aims Low-phospholipid-associated cholelithiasis (LPAC) syndrome, a rare genetic form of intrahepatic cholelithiasis in adults, is still poorly understood. We report the results of the largest-ever case-control study of patients with LPAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baa6f3598bde04f01c219301dcb5f0e
https://doi.org/10.1016/j.jhepr.2020.100201
https://doi.org/10.1016/j.jhepr.2020.100201