Massively Parallel Polymerase Cloning and Genome Sequencing of Single Cells Using the Microwell Displacement Amplification System (MIDAS)

Autor: Gole, Jeffrey

Publikováno v: Gole, Jeffrey. (2013). Massively Parallel Polymerase Cloning and Genome Sequencing of Single Cells Using the Microwell Displacement Amplification System (MIDAS) /. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/8kn4n1wd

Genome sequencing of single cells has a variety of applications, including characterizing difficult-to- culture microorganisms and identifying somatic mutations in single cells from mammalian tissues. A major hurdle in this process is the bias in amp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::3d7b509ade2e50ff09b81082a1b867d8
http://www.escholarship.org/uc/item/8kn4n1wd

The Genetics and Epigenetics of Induced Pluripotent Stem Cells

Autor: Gore, Athurva Jayavant

Publikováno v: Gore, Athurva Jayavant. (2013). The Genetics and Epigenetics of Induced Pluripotent Stem Cells. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/45j1149s

The ability to induce pluripotency in human adult somatic cells by defined transcription factor expression is a revolutionary prospect in regenerative medicine. This discovery has the potential to both open new research avenues for diseases in tissue

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http://www.escholarship.org/uc/item/45j1149s

DNA sequencing by denaturation

Autor: Chen, Ying-Ja

Publikováno v: Chen, Ying-Ja. (2009). DNA sequencing by denaturation. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6ks754v7

Genome sequencing technologies are in high demand for applications such as gene expressions, the studies of complex diseases, and personalized medicine. In this thesis, I present my work on a new DNA sequencing method called sequencing by denaturatio

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http://www.escholarship.org/uc/item/6ks754v7

On the systems characterization of metabolic networks

Autor: Jamshidi, Neema

Publikováno v: Jamshidi, Neema. (2009). On the systems characterization of metabolic networks. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/82x9q4fk

Significant progress has been made in the development of genome-scale models of metabolism in the past 15 years. The majority of the efforts have focused on the analysis of the right null space. While the steady state solution space is very important

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http://www.escholarship.org/uc/item/82x9q4fk

Mechanisms of post-myocardial infarction healing : from acute survival to chronic remodeling

Autor: Hunt, Darlene L.

Publikováno v: Hunt, Darlene L.(2009). Mechanisms of post-myocardial infarction healing : from acute survival to chronic remodeling. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/05r7k3t0

Acute survival and chronic healing after myocardial infarction (MI) depend on a myriad of processes that begin within hours of the injury and can continue in the form of remodeling even years thereafter. The myocardium has very little self-renewal ca

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http://www.escholarship.org/uc/item/05r7k3t0