Quantifying Expression and Loss of MiRNA in CLL B Cells and Plasma, and Modeling DEP Separation of B Cells, Plasma, and RNA From Blood

Autor: Tam, Ryan Wai

Publikováno v: Tam, Ryan Wai. (2015). Quantifying Expression and Loss of MiRNA in CLL B Cells and Plasma, and Modeling DEP Separation of B Cells, Plasma, and RNA From Blood. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0sf2693s

Chronic lymphocytic leukemia (CLL) is a form of blood cancer, in which DNA is mutated to produce abnormal B cell lymphocytes. CLL induces the cells to differentially regulate the expression of specific miRNA, producing miRNA with specific cancer rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::03970f960047ff2d3a3614b2d6dda0fb
http://www.escholarship.org/uc/item/0sf2693s

Minimally Intrusive Gaze Detection in Clinical Environments

Autor: Wang, Yuchen

Publikováno v: Wang, Yuchen. (2015). Minimally Intrusive Gaze Detection in Clinical Environments. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2j98f34k

Motivated by the Electronic Health Record (EHR) system's demand of capturing patients' multimodal activities and the wide application of gaze detection, we develop a minimally intrusive gaze detection system with Microsoft Kinect sensor and test its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::f5df2633af1580af3095f4447ebc051e
http://www.escholarship.org/uc/item/2j98f34k

Regulation of Mammalian Metabolism by Facilitated Transport Across the Inner Mitochondrial Membrane

Autor: Vacanti, Nathaniel Martin

Publikováno v: Vacanti, Nathaniel Martin. (2015). Regulation of Mammalian Metabolism by Facilitated Transport Across the Inner Mitochondrial Membrane. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7q8395fr

The enzymes and reactions of the metabolic network provide cells with a means to utilize the energy stored in substrate chemical bonds and to rearrange those bonds to form biosynthetic building blocks. The chapters of this dissertation are all indepe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::3acbd0c9317f5a1f140e132cb98565b7
http://n2t.net/ark:/20775/bb3278265r

Biochemical, Biomechanical and Cellular Investigation of Skeletal Muscle Fibrosis

Autor: Chapman, Mark Andrew

Publikováno v: Chapman, Mark Andrew. (2015). Biochemical, Biomechanical and Cellular Investigation of Skeletal Muscle Fibrosis. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/78q707jb

Skeletal muscle fibrosis is a condition that is characterized by an increase in extracellular matrix proteins, particularly collagen, in muscle. Fibrosis is a defining characteristic of muscle pathologies, where fibrotic scars decrease muscle strengt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::ee15d4e3110f7fddff4c5bc17f682133
http://www.escholarship.org/uc/item/78q707jb

The Role of Drug Transporters in Metabolism

Autor: Liu, Henry Chow-Heim

Publikováno v: Liu, Henry Chow-Heim. (2015). The Role of Drug Transporters in Metabolism. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/39523530

In this dissertation, a multi-leveled analysis is performed to understand the physiological functions of several key SLC/ABC transporters. First, a single transporter was studied, and then, the scope of study was extended to a set of 4 transporters;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::e9aa4fe389080bed5dafb3e1a3a989fe
http://n2t.net/ark:/20775/bb9660572k