Oral supplementation of healthy adults with 2′-O-fucosyllactose and lacto-N-neotetraose is well tolerated and shifts the intestinal microbiota

Autor: Peter Bytzer, Thierry Hennet, Emma Elison, Julie Rasmussen, Nikolaj Sørensen, Louise Kristine Vigsnæs, Bruce McConnell, Morten Otto Alexander Sommer, Laura Rindom Krogsgaard

Publikováno v: The British Journal of Nutrition
Elison, E, Vigsnæs, L K, Rindom Krogsgaard, L, Rasmussen, J, Sørensen, N, McConnell, B, Hennet, T, Sommer, M O A & Bytzer, P 2016, ' Oral supplementation of healthy adults with 2'-O-fucosyllactose and lacto-N-neotetraose is well tolerated and shifts the intestinal microbiota ', The British Journal of Nutrition, vol. 116, pp. 1356-1368 . https://doi.org/10.1017/S0007114516003354

The gut microbiota has been established as an important player influencing many aspects of human physiology. Breast milk, the first diet for an infant, contains human milk oligosaccharides (HMO) that shape the infant’s gut microbiota by selectively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ff01b7e7cd0e3e4abe5e71fd094049
https://doi.org/10.1017/s0007114516003354

Effect of chronic renal failure on the hepatic, intestinal and renal expression of bile acid transporters

Autor: Alex Odermatt, Jean-Pierre Montani, Lei Chu, Christian Hiller, Carlos A. Penno, Gerd A. Kullak-Ublick, Denis Arsenijevic, Zhibo Gai

Publikováno v: Am J Physiol Renal Physiol

Although the kidney is believed to play a minor role in bile acid (BA) excretion, chronic renal failure (CRF) has been reported to be associated with increased serum bile acid levels and alterations in BA homeostasis. The mechanisms for elevated BA l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf8534cec1f7c24fad05149f005ee9f
http://www.zora.uzh.ch/93444/

Structure-Based Identification of OATP1B1/3 Inhibitors

Autor: Pieter Annaert, Bruno Stieger, Tom De Bruyn, Adriaan P. IJzerman, Patrick Augustijns, Gerard J. P. van Westen, Peter de Witte

Publikováno v: Molecular Pharmacology. 83:1257-1267

Several recent studies show that inhibition of the hepatic transport proteins organic anion-transporting polypeptide 1B1 (OATP1B1) and 1B3 (OATP1B3) can result in clinically relevant drug-drug interactions (DDI). To avoid late-stage development drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b03ea19aba5f260047fde89727fca6
https://doi.org/10.1124/mol.112.084152

Blue–yellow colour vision impairment and cognitive deficits in occasional and dependent stimulant users

Autor: Katrin H. Preller, Michael Wagner, Lea M. Hulka, Daniela Jenni, Boris B. Quednow

Publikováno v: The International Journal of Neuropsychopharmacology
The international journal of neuropsychopharmacology / official scientific journal of the Collegium

Specific blue–yellow colour vision impairment has been reported in dependent cocaine users and it was postulated that drug-induced changes in retinal dopamine neurotransmission are responsible. However, it is unclear whether these changes are confi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281888af7216389b7dc69a751d6fbf88
http://www.zora.uzh.ch/64537/

Intrinsically photosensitive retinal ganglion cells are resistant to N-methyl-D-aspartic acid excitotoxicity

Autor: Sw, DeParis, C, Caprara, C, Grimm

Publikováno v: Molecular vision
Molecular Vision

Purpose Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin (OPN4) and are mainly responsible for non-image-forming visual tasks such as circadian photoentrainment and the pupillary light reflex. Compared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8757278e0113764670f298e4a5ac6798
https://doi.org/10.5167/uzh-68389