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of 80
pro vyhledávání: '"U. an der Heiden"'
Publikováno v:
Pharmacopsychiatry. 45:S2-S11
Emerging "(computational) systems medicine" challenges neuropsychiatry regarding the development of heuristic computational brain models which help to explore symptoms and syndromes of mental disorders. This methodology of exploratory modelling of me
Autor:
U. an der Heiden
Publikováno v:
Pharmacopsychiatry. 39:36-42
It is demonstrated that schizophrenia is a dynamical disease, i. e. that important aspects of schizophrenia can be understood on the basis of concepts of the theory of nonlinear dynamical systems. In particular, the gradual shift of a single paramete
Autor:
U. an der Heiden
The purpose of this work is a unified and general treatment of activity in neural networks from a mathematical pOint of view. Possible applications of the theory presented are indica ted throughout the text. However, they are not explored in de t
Publikováno v:
Mathematical Models and Methods in Applied Sciences. :521-541
In a first phenomenological part various forms of alcoholism and their classification are summarized. Our aim is to give an explanation of these patterns of alcohol consumption and addiction. Social, psychic, behavioral, and biochemico-physiological
Autor:
U. an der Heiden, J. Nauroschat
Publikováno v:
Journal of Mathematical Biology. 35:609-627
Structure and function of cells often depend critically on molecular signals arriving at their surface. There are universal mechanisms of signal transduction and signal processing across cell membranes. In this paper the mechanisms involving guanine-
Autor:
Christoph W. Turck, Felix Tretter, Peter J. Gebicke-Haerter, Dan Rujescu, U. an der Heiden, H. W. Mewes
Publikováno v:
Pharmacopsychiatry. 44
Understanding mental disorders and their neurobiological basis encompasses the conceptual management of "complexity" and "dynamics". For example, affective disorders exhibit several fluctuating state variables on psychological and biological levels a
Publikováno v:
Pharmacopsychiatry. 42
The onset of addiction is marked with drug induced positive experiences that keep being repeated. During that time, adaptation occurs and addiction is stabilized. Interruption of those processes induces polysymptomatic withdrawal syndromes. Abstinenc
Publikováno v:
Journal of Dynamics and Differential Equations. 2:423-449
Solution properties of the nonlinear second-order delay-differential equation x(t)=−ax(t)+f[x(t−Τ)] are studied wheref is a piecewise constant function which mimics negative feedback. We show that the solutions can be obtained by a simple geomet
Autor:
Monika Joanna Piotrowska, Darius Widera, Christian Kaltschmidt, Barbara Kaltschmidt, U. an der Heiden
Neural stem cells (NSCs) are early precursors of neuronal and glial cells. NSCs are capable of generating identical progeny through virtually unlimited numbers of cell divisions (cell proliferation), producing daughter cells committed to differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793402a2a0dbcfb274c9a748386aa62a
https://pub.uni-bielefeld.de/record/1913673
https://pub.uni-bielefeld.de/record/1913673
Autor:
U, an der Heiden
Publikováno v:
Medizinische Klinik (Munich, Germany : 1983). 93(9)