Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure

Autor: Milton Packer, John J.V. McMurray, Henry Krum, Wolfgang Kiowski, Barry M. Massie, Avi Caspi, Craig M. Pratt, Mark C. Petrie, David DeMets, Isaac Kobrin, Sebastien Roux, Karl Swedberg, Craig Pratt, Barry Massie, John McMurray, Eugene Connally, Mark Petrie, Susan Anderson, Jody Barnet, Robert Cody, Henry Dargie, Gary Francis, Barry Greenberg, Juerg Reichen, J. Karrasch, H. Krum, J. Horowitz, J. Amerena, A. Sindone, P. MacDonald, I. Jeffrey, I. Button, E. DeAngelis, R. Pacher, R. Davies, F. McAlister, P. Tanser, B. Sussex, G. Baumann, E. Fleck, H.-G. Olbrich, K. Werdan, H. Klein, F. Staffeld, A.M. Zeiher, C. Roediger, A. Caspi, A. Marmor, L. Reisin, Z. Vered, E. Klainman, N. Roguin, D. Tzivoni, D. David, B. Lewis, E. Abinader, M. Omary, Y. Rosenman, E. Kaluski, R.W. Breedveld, P.H. van der Burgh, P.H.J.M. Dunselman, H.J. Schaafsma, D.P. Hertzberger, N.J. Holwerda, J.A. Kragten, J. van Wijngaarden, J.L. Posma, S.A.M. Said, L.C. Slegers, R.M. Tjon Joe Gin, F.N. Wempe, J.C.L. Wesdorp, A.R. Willems, A.J.A.M. Withagen, J.M. Cornel, L.H.J. van Kempen, W. Kiowski, O. Bertel, T. Moccetti, J.J.V. McMurray, R.A. Greenbaum, P. Bennett, J. Swan, G. Davies, I. Findlay, B. Gould, S. Ball, P. Hubner, A. Lahiri, J. McLay, R. Northcote, S. Saltissi, I. Squire, J. Stephens, M. Stewart, G. Bridgen, J. Walsh, D.J. Webb, Z. Ansari, S. Baron, R. Bellinger, W. Bennet, D. Benvenuti, D. Dawley, L.C. Egbujiobi, I. Eisenstein, T. Little, A. Hertsberg, M. Greenspan, R.J. Grossman, P. Hanley, M. Jesrani, H. Kashou, R. Levites, R. Malik, B. Marmorstein, M. Schwartz, A. Nisar, R. Perelman, M.L. Schwarz, S. Sedlis, J. Srebro, M. Taveras, R. Weiss, P. Weitzman, G.K. Wetherley, M. El Shahawy, D. Kereiakes, L. Campos, G. Peterson, R.S. Small, W.R. Davis, M.-T. Olivari, W. Meengs, M. Koren, P. Slagona, S. Jennison, R. Hershberger, K.F. Browne, D.J. Farnham, S. Zelenkofske, C. Lawless, M. Nathan, T. Meyer, M. Kukin, H. Parekh, R. Berkowitz, J. Boehmer, S. Brozena, P. Dandona, G.W. Dec, V. DeQuattro, P. Fenster, M. Fowler, S. Ellaham, M. Geller, M. Gheorgiade, J. Ghali, S. Murali, S. Katz, C. Bott-Silverman, B. Singh, U. Thadani, G. Torre, J. Teerlink, T. Chandraratna, M. Kesselbrenner, A. Mukherjee, C. Che-Pin Tsai, K. Abbo, M. Goldberg, T. Smith, R.T. Martin

Publikováno v: JACC: Heart Failure. 5:317-326

Objectives The objective of this clinical trial was to evaluate the long-term effect of endothelin receptor antagonism with bosentan on the morbidity and mortality of patients with severe chronic heart failure. Background Endothelin may play a role i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb048a52ef9808b8c1bc2dbcf796ca66
https://doi.org/10.1016/j.jchf.2017.02.021

Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF)

Autor: P. Alagona, R. Touchon, P. Eliasen, G. Uhl, A. Stogowski, L. Missault, K. Sándori, Fach, L. Swenson, K. L. Neuhaus, R. Carlson, K. Egstrup, M. Halinen, M. Maltz, T. Gundersen, Girth, M. Hetey, Goss, P. N.W.M. Breuls, R. Breedveld, Z. Ansari, P. Batin, J. D. Pappas, S. Hutchins, G. Veress, K. Wrabec, Allan D. Struthers, H. Berwing, Thilo, Mäurer, A. Katona, C. J. Weaver, J. C.L. Wesdorp, J. Rokkedal Nielsen, D. Dwyer, J. J.J. Bucx, M. Nannan, Obst, J. Tarján, Neuhaus, H. R. Michels, D. El Allaf, B. Silverman, M. J. Tonkon, J. Juvonen, C. Berthe, W. Old, T. L. Hole, P. Petr, R. Shah, Gu Thorgeirsson, P. Mohacsi, Konz, B. Krosse, István Czuriga, Robert J. Weiss, Johan Herlitz, H. J. Willens, John Wikstrand, S. Jafri, Kenneth Dickstein, B. Oze, Jiri Vitovec, Harold L. Kennedy, H. Madyoon, Dück, G. Westergren, J. H. Rosen, Prakash Deedwania, A. C. Bredero, John Kjekshus, J. L. Vandenbossche, P. Decroly, D. A. Goldscher, B. Lüderitz, Uri Elkayam, W. Kao, Bethge, Martin R. Berk, J. Smíd, J. R. Wilson, P. Kaiser-Nielsen, M. Lundström, P. Fenster, M. Imburgia, Bischoff, H. Schläpfer, J. H. Hall, J. Mannsverk, K. J.G. Schmailzl, M. Lengyel, T. Saleem, P. A. de Milliano, M. Rotman, Löbe, P. E. Nielsen, A. Kána, G. P. Gooden, Beythien, G. Goldberg, K. J. Vaska, Hahn, Sidney Goldstein, J. Aldershvile, Eichler, H. J. Schaafsma, Lewek, Irving K. Loh, Mark E. Dunlap, K. Dvorák, S. Promisloff, J. Tenczer, Simon, M. Sveinsdottir, Björn Fagerberg, M. T. Hattenhauer, P. Timmermans, A. M. Rashkow, I. Balla, B. Jackson, K. E. Berkin, H. Völler, A. Nyárádi, M. Goodman, R. Bhalla, W. Jauch, M. Thimell, A. H. Liem, J. Farnham, S. Friedman, P. L. Schwimmbeck, Hans Wedel, G. Linssen, Finn Waagstein, R. J.T. Taverne, J. Forfar, J. Shanes, Peter K. Smith, J. W. Piotrowski, L. O. Hemmingson, M. O'Shaughnessy, M. El Shahawy, F. Pedersen, B. H. Kahn, B. J.B. Hamer, P. Sijbring, K. Syed, Mihai Gheorghiade, G. Tildesley, W. J. Wickemeyer, M. F. Lesser, B. Lernfelt, B. Andersson, Peter H.J.M. Dunselman, P. Kolodziej, Y. Shalev, S. Ekdahl, P. A.G. Zwart, Seth Bilazarian, A. J.A.M. Withagen, András Jánosi, Darius, Z. Kornacewicz-Jach, Odemar, W. Motz, G. F. Hauf, G. Vandenhoven, D. H. Kraus, K. Kaplan, A. R. Ramdat Misier, P. Nesje, R. Polikar, Ge Thorgeirsson, Peter Rickenbacher, T. Hack, Weibrodt, Stephen G. Ball, K. Danisa, A. Nisar, J. Swan, K. Ångman, Wirtz, Rainer Dietz, J. Toman, C. O. Gotzsche, J. Stephens, K. F. Browne, Schröder, Daniel, Åke Hjalmarson, J. Alderman, J. C.A. Hoorntje, K. Hofsoy, P. Vályi, P. Hildebrandt, K. Zámolyi, M. Levy, J. W. Viersma, G. Boxho, M. Dahle, D. M. Denny, H. Nielsen, A. Rednik, Strasser, R. Wright, J. Feyzi, B. Dorhout, Jan H. Cornel, C. J. Carlson, A. Abbasi, Richard M. Steingart, A. R. Willems, Jalal K. Ghali, R. Gillespe, Stephen S. Gottlieb, P. Svítil, D. Murdoch, D. Benvenuti, Klocke, A. Edmiston, H. A. Tjonndal, J. L. Anderson, T. S. Callaghan, M. B. Higginbotham, O. Vikesdal, O. Samuelsson, J. Rinne, W. Van Mieghem, T. Giles, E. Bucher, A. Förster, L. Holmberg, Schrader, P. Erne, K. Chatterjee, K. LaBresh, S. V. Savran, G. L. Maurice, M. Krzemiñska-Pakula, Hepp, E. Agner, Maier, G. S. Froland, H. Jääskeläinen, M. Alipour, W. Piwowarska, J. Pirlet, T. M. Omland, B. J. Iteld, J. Kuch, Shmuel Gottlieb, Janka, R. DiBianco, P. Karpati, K. Jaworska, Marcus A. Dewood, Ira Dauber, T. Honkanen, R. D. Thorsen, S. Danker, J. M. Boutefeu, J. Hoogsteen, I. Szczurko, B. T. Beanblossom, C. J.P.J. Werter, S. Jennison, J. Wodniecki, T. Salonen, A. Johannesen, J. Rybka, G. Dennish, P. M. Diller, L. Goodman, Bundschu, J. P. Galichia, Johannes A. Kragten, S. Timar, K. Skagen, R A Greenbaum, L. Yellen, J. Gorwit, Michael R. Geller, D. Andresen, J. J. Kennedy, K. E. von Olshausen, J. P. Derbaudrenghien, R. Van Stralen, N. Holwerda, J. L. Vachiery, S. Lehto, T. Heywood, F. Maislos, R. K. Lewis, R. Bjornerheim, Adamus, K. Phadke, M. J. Veerhoek, Pomykaj, M. C. Goldberg, Nast, Hambrecht, O. Amtorp, Vöhringer, David L. DeMets, R. Levites, W. Meyer-Sabellek, G. Heyndrickx, G. Reynolds, E. Scott, P. Dunselman, C. Sjödin, M. Sigmund, M. Ashraf, C. MBuchter, I. Nováková, Delius, Philip D. Henry, Ronald P. Karlsberg, P. J. Van Veldhuisen, Drude, M. Herold, U. Thadani, L. Kirkegaard, H. Nilsson B Widgren, S. G. Wagner, S. Bennett, E. Hussi, K. Dowd, B. Reeves, Lars Gullestad, Douglas L. Mann, C. Larsson, Gudmundur Thorgeirsson, Heinemann, K. Waage, P. Szabó, L. Lalonde, Michael P. Frenneaux, D. Grech, D. G. Julian, P. Ahlström, T. Johansen, Melchior, Kühlkamp, Dingerkus, L. H.J. Van Kempen, A. Hildebrandt, A. Gradman, Jaromír Hradec, Müller, P. J.L.M. Bernink

Publikováno v: The Lancet. 353:2001-2007

BACKGROUND: Metoprolol can improve haemodynamics in chronic heart failure, but survival benefit has not been proven. We investigated whether metoprolol controlled release/extended release (CR/XL) once daily, in addition to standard therapy, would low

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9bb4d92786073c126b0db5f27722642
https://doi.org/10.1016/s0140-6736(99)04440-2

Liposomal PGE-1 adjunctive treatment for acute myocardial infarction: final results of the LIFT pilot trial

Autor: Y.C. Park, J.J. Freitag, U. Thadani, E. Bates, D. Moliterno, D.G. Ebersole, R. Werner, G.B. Habib, R.P. Karlsberg, Richard W. Smalling

Publikováno v: Journal of the American College of Cardiology. 31

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d0707e13dacc99566d445dd9e05650

Effects of zatebradine (ULFS 49 CL), a sinus node inhibitor, on heart rate and exercise duration in chronic stable angina pectoris. Zatebradine Investigators

Autor: S P, Glasser, D D, Michie, U, Thadani, W M, Baiker

Publikováno v: The American journal of cardiology. 79(10)

Zatebridine selectively reduces resting and exercise heart rate without any other myocardial effects. In this study, despite significant reductions in resting and exercise heart rate, there were no clinically significant effects on myocardial ischemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be4be65827e359419e000a8b5fa17ad6
https://pubmed.ncbi.nlm.nih.gov/9165168

Dose-response evaluation of once-daily therapy with a new formulation of diltiazem for stable angina pectoris. Diltiazem CD Study Group

Autor: U, Thadani, S, Glasser, N, Bittar, C L, Beach

Publikováno v: The American journal of cardiology. 74(1)

Diltiazem hydrochloride in a once-daily capsule formulation (DCD) has recently been approved in the United States for the treatment of mild to moderate hypertension and chronic stable angina pectoris. This trial evaluated the dose response of DCD in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76139ade60767f6924343e53829faae1
https://pubmed.ncbi.nlm.nih.gov/8017316