Reduced prescription of TNF-inhibitors in chronic arthritis based on therapeutic drug monitoring: A randomized controlled trial

Autor: M Pfeiffer-Jensen, D Liao, U Tarp, B Deleuran, K Stengaard-Pedersen, J Venborg, B Brock, C Brock

Publikováno v: Pfeiffer-Jensen, M, Liao, D, Tarp, U, Deleuran, B, Stengaard-Pedersen, K, Venborg, J, Brock, B & Brock, C 2022, ' Reduced prescription of TNF-inhibitors in chronic arthritis based on therapeutic drug monitoring : A randomized controlled trial ', Scandinavian Journal of Rheumatology . https://doi.org/10.1080/03009742.2022.2121081

OBJECTIVE: Dosing of tumour necrosis factor-α inhibitors (TNFis) is not personalized causing interindividual variation in serum drug levels; however, dose optimization is not widely implemented. We hypothesized that some patients are overdosed; thus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9fc14e1f44e074fb71ff7b75fe3f636

Effect of a treat-to-target cyclosporin on MRI-assessed synovitis, osteitis, tenosynovitis, bone erosion, and joint space narrowing in early rheumatoid arthritis: results from a 2-year randomized double-blind

Autor: S Møller-Bisgaard, BJ Ejbjerg, I Eshed, K Hørslev-Petersen, ML Hetland, AG Jurik, H Thomsen, T Torfing, K Stengaard-Pedersen, P Junker, NS Krogh, T Lottenburger, T Ellingsen, LS Andersen, H Skjødt, AJ Svendsen, U Tarp, IT Hansen, J Pødenphant, JK Pedersen, H Lindegaard, LG Hanson, A Vestergaard, D Glinatsi, M Østergaard

Objectives: To investigate whether a treat-to-target strategy based on methotrexate (MTX) and intra-articular (IA) betamethasone suppresses magnetic resonance imaging (MRI)-determined measures of disease activity and reduces joint destruction in earl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::056b294dc837f7932e9400844f4f066e

Periarticular and generalised bone loss in patients with early rheumatoid arthritis: influence of alendronate and intra-articular glucocorticoid treatment. Post hoc analyses from the CIMESTRA trial

Autor: T W, Jensen, M S, Hansen, K, Hørslev-Petersen, L, Hyldstrup, B, Abrahamsen, B, Langdahl, B, Zerahn, J, Pødenphant, K, Stengaard-Petersen, P, Junker, M, Østergaard, T, Lottenburger, T, Ellingsen, L S, Andersen, I, Hansen, H, Skjødt, J K, Pedersen, U B, Lauridsen, A J, Svendsen, U, Tarp, H, Lindegaard, Anne Grethe, Jurik, Aage, Vestergaard, M L, Hetland, K B, Lorentzen

Publikováno v: Jensen, T W, Hansen, M S, Hørslev-Petersen, K, Hyldstrup, L, Abrahamsen, B, Langdahl, B L, Zerahn, B, Pødenphant, J, Stengaard-Pedersen, K, Junker, P, Ostergaard, M, Lottenburger, T, Ellingsen, T, Andersen, L S, Hansen, I T, Skjødt, H, Pedersen, J K, Lauridsen, U B, Svendsen, A J, Tarp, U, Lindegaard, H, Jurik, A G, Vestergaard, A, Hetland, M L & the CIMESTRA study group 2014, ' Periarticular and generalised bone loss in patients with early rheumatoid arthritis : influence of alendronate and intra-articular glucocorticoid treatment. Post hoc analyses from the CIMESTRA trial ', Annals of the Rheumatic Diseases, vol. 73, no. 6, pp. 1123-1129 . https://doi.org/10.1136/annrheumdis-2012-203171
Jensen, T W, Hansen, M S, Hørslev-Petersen, K, Hyldstrup, L, Abrahamsen, B, Langdahl, B L, Zerahn, B, Pødenphant, J, Stengaard-Petersen, K, Junker, P, Ostergaard, M, Lottenburger, T, Ellingsen, T, Andersen, L S, Hansen, I, Skjødt, H, Pedersen, J K, Lauridsen, U B, Svendsen, A J, Tarp, U, Lindegaard, H, Jurik, A G, Vestergaard, A, Hetland, M L & the Cimestra study group 2014, ' Periarticular and generalised bone loss in patients with early rheumatoid arthritis : influence of alendronate and intra-articular glucocorticoid treatment. Post hoc analyses from the CIMESTRA trial ', Annals of the Rheumatic Diseases, vol. 73, no. 6, pp. 1123-1129 . https://doi.org/10.1136/annrheumdis-2012-203171

Objectives: The aims of this study were to investigate the influence of alendronate and intra-articular betamethasone treatment on bone mineral density (BMD) changes in hand, lumbar spine and femoral neck during 1 year of a treat-to-target study (Cyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bd21ebdfd283d027631ba14d1f3d42
https://pubmed.ncbi.nlm.nih.gov/23661492

MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis:Results from af 2 year randomized controlled trial (CIMESTRA)

Autor: M L, Hetland, B, Ejbjerg, K, Hørslev-Petersen, S, Jacobsen, A, Vestergaard, A G, Jurik, K, Stengaard-Pedersen, P, Junker, T, Lottenburger, I, Hansen, L S, Andersen, U, Tarp, H, Skjødt, J K, Pedersen, O, Majgaard, A J, Svendsen, T, Ellingsen, H, Lindegaard, A F, Christensen, J, Vallø, T, Torfing, E, Narvestad, H S, Thomsen, M, Ostergaard, B, Pedersen-Zbinden

Publikováno v: Hetland, M L, Ejbjerg, B J, Hørslev-Petersen, K, Jacobsen, S, Vestergaard, A, Jurik, A G, Stengaard-Pedersen, K, Junker, P, Lottenburger, T, Hansen, I, Andersen, L S, Tarp, U, Skjødt, H, Pedersen, J K, Majgaard, O, Svendsen, A J, Ellingsen, T, Lindegaard, H M, Christensen, A F, Vallø, J, Torfing, T, Narvestad, E, Thomsen, H S & Ostergaard, M 2008, ' MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis : Results from af 2 year randomized controlled trial (CIMESTRA). ', Annals of the Rheumatic Diseases, vol. 68, no. 3, pp. 384-390 . https://doi.org/10.1136/ard.2008.088245
Hetland, M L, Ejbjerg, B J, Hørslev-Petersen, K, Jacobsen, S, Vestergaard, A, Jurik, A G, Stengaard-Pedersen, K, Junker, P, Lottenburger, T, Hansen, I, Andersen, L S, Tarp, U, Skjødt, H, Pedersen, J K, Majgaard, O, Svendsen, A J, Ellingsen, T, Lindegaard, H M, Christensen, A F, Vallø, J, Torfing, T, Narvestad, E, Thomsen, H S & Ostergaard, M 2008, ' MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis. Results from a 2 year randomized controlled trial (CIMESTRA) ', Annals of the Rheumatic Diseases . https://doi.org/10.1136/ard.2008.088245

Objective:To identify predictors of radiographic progression in a 2-year randomised, double-blind, clinical study (CIMESTRA) of patients with early rheumatoid arthritis (RA).Methods:Patients with early RA (n = 130) were treated with methotrexate, int

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https://portal.findresearcher.sdu.dk/da/publications/0d8e53d0-4440-11dd-9fbe-000ea68e967b

SAT0409 Association between Tobacco Smoking and Response to Tumor Necrosis Factor Alpha Inhibitor Treatment in Psoriatic Arthritis: Results from the Danbio Registry

Autor: P. Højgaard, B. Glintborg, M.L. Hetland, T.H. Hansen, C. Nilsson, P.R. Lage-Hansen, M.H. Petersen, M. Holland-Fisher, A.G. Loft, B.N. Andersen, T. Adelsten, J. Jensen, E. Omerovic, R. Christensen, U. Tarp, R. Østgaard, L. Dreyer

Publikováno v: Annals of the Rheumatic Diseases. 73:743.1-743

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af3cd94fb6d84254f47ebd550ebfb77b
https://doi.org/10.1136/annrheumdis-2014-eular.2326