Zobrazeno 1 - 10
of 20
pro vyhledávání: '"U. Ruth Michaelis"'
Cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) are important modulators of endothelial cell homeostasis. We investigated the signaling pathway linking the activation of CYP 2C9 to enhanced endothelial cell proliferation. Overexpressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bb282c157b4a56a24c35dea52460b3
http://edoc.mdc-berlin.de/19287/1/19287oa.pdf
http://edoc.mdc-berlin.de/19287/1/19287oa.pdf
Autor:
Claudia Döring, Carmen Urbich, Tanja Mändle, U. Ruth Michaelis, Kirsten Lauber, Fiona O’Rourke, Matthias Flötenmeyer, Stefanie Dimmeler, Ralf P. Brandes, Martin-Leo Hansmann, Volkhard A. J. Kempf, Wibke Ballhorn
Publikováno v:
Cellular Microbiology. 17:1447-1463
Summary The contribution of myeloid cells to tumour microenvironments is a decisive factor in cancer progression. Tumour-associated macrophages (TAMs) mediate tumour invasion and angiogenesis through matrix remodelling, immune modulation and release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7a80322a4f2b0b59db9c0e91ce58b69
https://doi.org/10.1111/cmi.12447
https://doi.org/10.1111/cmi.12447
Autor:
Johannes A. Eble, Benno Jungblut, Katalin Wandzioch, U. Ruth Michaelis, Michael Potente, Jean-Paul Borg, Marie-Josée Santoni, Emmanouil Chavakis, Heinrich Heide, Christoph Kruse, Ralf P. Brandes, Yosif Manavski, David Kaluza
Publikováno v:
Circulation Research. 112:924-934
Rationale: Polarity proteins are involved in the apico-basal orientation of epithelial cells, but relatively little is known regarding their function in mesenchymal cells. Objective: We hypothesized that polarity proteins also contribute to endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c44e7dd6ac4d3fddf6d172ea94e4ba
https://doi.org/10.1161/circresaha.112.300592
https://doi.org/10.1161/circresaha.112.300592
Autor:
Anja Mieth, U. Ruth Michaelis, Min Zhang, Ralf P. Brandes, Judith Kosowski, Rainer U. Pliquett, Peter Luedike, Sebastian Benkhoff, Norbert Weissmann, Stefanie Dimmeler, Katrin Schröder, Christoph Kruse, Ajay M. Shah
Publikováno v:
Circulation Research. 110:1217-1225
Rationale: The function of Nox4, a source of vascular H 2 O 2 , is unknown. Other Nox proteins were identified as mediators of endothelial dysfunction. Objective: We determined the function of Nox4 in situations of increased stress induced by ischemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7419480bd3bb1011304a69ff07178c
https://doi.org/10.1161/circresaha.112.267054
https://doi.org/10.1161/circresaha.112.267054
Autor:
U. Ruth Michaelis, Ralf P. Brandes, Norbert Weissmann, Ina Takac, Masamichi Koyanagi, Katrin Schröder, Sina Batz, Susanne Schutz, Isabella Schlöffel
Publikováno v:
Antioxidants & Redox Signaling. 15:915-923
Hepatocyte growth factor (HGF) by stimulating the receptor tyrosine kinase c-Met induces angiogenesis and tissue regeneration. HGF has been shown to antagonize the angiotensin II-induced senescence of endothelial progenitor cells (EPCs), which is med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370ff7277b9c7207e8625e502945a7e5
https://doi.org/10.1089/ars.2010.3533
https://doi.org/10.1089/ars.2010.3533
Autor:
John R. Falck, Riidiger Popp, Andiappan Murugan, Beate Fisslthaler, Ingrid Fleming, U. Ruth Michaelis, Eduardo Barbosa-Sicard, Anke C. Webler
Publikováno v:
American Journal of Physiology-Cell Physiology. 295:C1292-C1301
Cytochrome P-450 (CYP) epoxygenases metabolize arachidonic acid to epoxyeicosatrienoic acid (EET) regioisomers, which activate several signaling pathways to promote endothelial cell proliferation, migration, and angiogenesis. Since vascular endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595617d9852e483f81b163ee31df27dd
https://doi.org/10.1152/ajpcell.00230.2008
https://doi.org/10.1152/ajpcell.00230.2008
Autor:
Fiona, O'Rourke, Tanja, Mändle, Carmen, Urbich, Stefanie, Dimmeler, U Ruth, Michaelis, Ralf P, Brandes, Matthias, Flötenmeyer, Claudia, Döring, Martin-Leo, Hansmann, Kirsten, Lauber, Wibke, Ballhorn, Volkhard A J, Kempf
Publikováno v:
Cellular microbiology. 17(10)
The contribution of myeloid cells to tumour microenvironments is a decisive factor in cancer progression. Tumour-associated macrophages (TAMs) mediate tumour invasion and angiogenesis through matrix remodelling, immune modulation and release of pro-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b431687320b5a8e104980611b02d732b
https://pubmed.ncbi.nlm.nih.gov/25857345
https://pubmed.ncbi.nlm.nih.gov/25857345
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:321-326
Objective— Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to epoxyeicosatrienoic acids (EETs). CYP2C9-derived EETs elicit endothelial cell proliferation and angiogenesis, but the signaling pathways involved are incompletely understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20461f74fc10f64bf714d21fad7a10ec
https://doi.org/10.1161/01.atv.0000151648.58516.eb
https://doi.org/10.1161/01.atv.0000151648.58516.eb
Autor:
U. Ruth Michaelis, Beate Fisslthaler, Voahanginirina Randriamboavonjy, Rudi Busse, Ingrid Fleming
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1619:332-339
Over the last 10 years it has become increasingly clear that cytochrome P450 (CYP) enzymes expressed within endothelial and vascular smooth muscle cells play a crucial role in the modulation of vascular homeostasis. There is strong evidence suggestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a43cc761831e71b6a5ca855ddaa36fb
https://doi.org/10.1016/s0304-4165(02)00492-0
https://doi.org/10.1016/s0304-4165(02)00492-0
Autor:
U. Ruth Michaelis
Publikováno v:
Cellular and molecular life sciences : CMLS. 71(21)
Cell migration plays a central role in a variety of physiological and pathological processes during our whole life. Cellular movement is a complex, tightly regulated multistep process. Although the principle mechanisms of migration follow a defined g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43d2796841588cde68ec483f882aa81
https://pubmed.ncbi.nlm.nih.gov/25038776
https://pubmed.ncbi.nlm.nih.gov/25038776