Zobrazeno 1 - 10
of 95
pro vyhledávání: '"U. R. Rapp"'
Autor:
U. R. Rapp, R. Schreck
Publikováno v:
Der Onkologe. 10:S64-S68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56470fa9e8da1bbf9fc1489d1ab6bccb
https://doi.org/10.1007/s00761-003-0649-0
https://doi.org/10.1007/s00761-003-0649-0
Autor:
T. Twardzik, U. R. Rapp
Publikováno v:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 45:79-84
Stammzellen sind an der Bildung und Entwicklung vieler Gewebe und spezialisierter Zelltypen eines Organismus beteiligt. Dabei ist die Ausbildung der Zelltypen eines menschlichen Organismus nicht auf die fruhe Embryonalentwicklung beschrankt. Auch im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a175d12a26489fa369afb5a406574d1c
https://doi.org/10.1007/s00103-001-0345-4
https://doi.org/10.1007/s00103-001-0345-4
Publikováno v:
Journal of Biological Chemistry. 269:7337-7341
Although a pathway that requires sequential activation of Ras, Raf, and MAP kinase kinase has been proposed as the major mechanism for stimulation of mitogen-activated protein kinase (MAP kinase), alternative pathways also exist. A wide variety of ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::755c4f84d1a9a4b9ebe5b9e929956b32
https://doi.org/10.1016/s0021-9258(17)37289-7
https://doi.org/10.1016/s0021-9258(17)37289-7
Publikováno v:
The Journal of Immunology. 151:4116-4127
The c-Raf-1 serine/threonine kinase is an important component of signal transduction pathways mediating the effects of a variety of growth factors. In activated T cells, IL-2 has been shown to induce activation of c-Raf-1, but c-Raf-1 has not previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c53d7132315b1efde4fb885e711e66
https://doi.org/10.4049/jimmunol.151.8.4116
https://doi.org/10.4049/jimmunol.151.8.4116
Autor:
K. Alexandropoulos, S. A. Qureshi, U. R. Rapp, David A. Foster, J. T. Bruder, Myunghi Rim, C K Joseph
Publikováno v:
Journal of Biological Chemistry. 267:17635-17639
v-Src activates promoters under the control of 12-O-tetradecanoylphorbol-13-acetate (TPA) response elements (TREs) and serum response elements (SREs) via two distinguishable intracellular signaling mechanisms. The induction of TRE- and SRE-mediated g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de497a73bc33d7f1f30a19fe506256c8
https://doi.org/10.1016/s0021-9258(19)37090-5
https://doi.org/10.1016/s0021-9258(19)37090-5
Publikováno v:
Molecular and Cellular Biology. 12:3733-3742
B-Raf, a member of the Raf family of serine/threonine kinases, is expressed primarily in the brain and in the nervous system. In this study, the biochemical properties of the B-Raf protein were investigated in nerve growth factor (NGF)-responsive cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f80fa706a224ca109fed370b96af0ff2
https://doi.org/10.1128/mcb.12.9.3733
https://doi.org/10.1128/mcb.12.9.3733
Autor:
Bernard Binétruy, Dan Mercola, G Heidecker, A Grover-Bardwick, Michael Karin, U R Rapp, Tod Smeal
Publikováno v:
Molecular and Cellular Biology. 12:3507-3513
In resting cells, c-Jun is phosphorylated on five sites. Three of these sites reside next to its DNA binding domain and negatively regulate DNA binding. In response to expression of oncogenic Ha-Ras, phosphorylation of these sites decreases, while ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e04c35883af33336d300e29aff95120
https://doi.org/10.1128/mcb.12.8.3507
https://doi.org/10.1128/mcb.12.8.3507
Autor:
U. R. Rapp, Vikas P. Sukhatme, Myunghi Rim, David A. Foster, S. A. Qureshi, Walter Kolch, J. T. Bruder
Publikováno v:
Scopus-Elsevier
The protein-tyrosine kinase activity of v-Src leads to the transcriptional activation of the mitogen-responsive transcription factor Egr-1. c-Raf-1 is a serine/threonine protein kinase that has been implicated in the transduction of signals induced b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12574bd9a4294a5718d1337fc3e206a
https://doi.org/10.1016/s0021-9258(18)54750-5
https://doi.org/10.1016/s0021-9258(18)54750-5
Publikováno v:
Biochemical Journal. 278:43-47
Sinusoidal Ito cells (stellate or fat-storing cells) undergo excessive cellular proliferation before the establishment and progression of hepatic fibrosis and cirrhosis. Retinoic acid and transforming growth factor beta (TGF beta) both inhibit Ito-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfaf13f0b7fde8ca117e5bde8d55894
https://doi.org/10.1042/bj2780043
https://doi.org/10.1042/bj2780043
Publikováno v:
Journal of Biological Chemistry. 266:14964-14969
Erythropoietin mediates the rapid phosphorylation of Raf-1 in the murine cell lines HCD-57 and FDC-P1/ER, which proliferate in response to this cytokine. Phosphorylation occurs at both serine and tyrosine residues and as such is similar to the Raf-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b39c4e74f3b8633d984e74d3ef03dbd
https://doi.org/10.1016/s0021-9258(18)98572-8
https://doi.org/10.1016/s0021-9258(18)98572-8