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Autor:
Ingrid Fleming, Oliver Werz, Daniel Eikel, Heinz Nau, Hans Wilhelm Doerr, Jindrich Cinatl, K Beek, Martin Michaelis, Tatyana Suhan, Florian Rothweiler, L Tausch, U. R Michaelis, M Zörnig
Publikováno v:
Cell death and differentiation. 13(3)
The histone deacetylase (HDAC) inhibitor valproic acid (VPA) was recently shown to inhibit angiogenesis, but displays no toxicity in endothelial cells. Here, we demonstrate that VPA increases extracellular signal-regulated kinase 1/2 (ERK 1/2) phosph