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pro vyhledávání: '"U. Panten"'
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Publikováno v:
Energetics of Secretion Responses ISBN: 9781315150987
Energetics of Secretion Responses
Energetics of Secretion Responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b9373a558f3b8a3ea07ef163f4eeaa
https://doi.org/10.1201/9781315150987-7
https://doi.org/10.1201/9781315150987-7
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Publikováno v:
Annalen der Physik. 522:53-59
Autor:
U. Panten, Ingo Rustenbeck
Publikováno v:
Diabetologia. 51:101-109
The aim of this study was to examine whether the cytosolic NADPH/NADP+ ratio of beta cells serves as an amplifying signal in fuel-induced insulin secretion and whether such a function is mediated by cytosolic alpha-ketoglutarate.Pancreatic islets and
Publikováno v:
Europe PubMed Central
1. The temporal relationship between the early glucose-induced changes of membrane potential and cytoplasmic Ca2+ concentration ([Ca2+]i) was studied in insulin-releasing pancreatic beta-cells. 2. The mean resting membrane potential and [Ca2+]i were
Publikováno v:
Pharmacology. 50:182-191
Recently evidence was presented that fluorescein derivatives (e.g. phloxine B) inhibit glibenclamide binding by occupation of a nucleotide-binding site at the ATP-sensitive potassium channel (KATP channel). However, this conclusion was inconsistent w
Publikováno v:
Journal of Biological Chemistry. 269:17768-17771
Previous studies have described specific photoincorporation of radiolabeled sulfonylureas into a peptide with high molecular mass (140-175 kDa), which thus has been suggested to represent the sulfonylurea receptor. In the present study, a 125I-labele
Publikováno v:
Biochemical pharmacology. 80(1)
The K(+) channel blocker, TEA is known to increase action potential amplitude and insulin secretion of mouse beta-cells when added to a nutrient secretagogue. In the presence of a maximally effective sulfonylurea concentration (2.7 microM glipizide)
Publikováno v:
Hormone and Metabolic Research. 24:549-554
The hypoglycemic effect of sulfonylureas and their analogues results from their binding to a high affinity site in the B-cell plasma membrane. This site seems to be a structural component of the ATP-sensitive K(+)-channel and represents the pancreati