Zobrazeno 1 - 10
of 174
pro vyhledávání: '"U. Mengs"'
Publikováno v:
Archives of Toxicology. 80:34-44
Senna (Tinnevelly senna fruits), a known laxative derived from plants, was administered by gavage to Sprague-Dawley (Crl:CD (SD) BR) rats once daily at dose levels of 0, 25, 100 and 300 mg/kg/day for up to 104 consecutive weeks. Based upon clinical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc25823fc8dbfa99cb44a37ffd4a972
https://doi.org/10.1007/s00204-005-0021-9
https://doi.org/10.1007/s00204-005-0021-9
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 492:69-72
Chrysophanol is an anthraquinone which occurs in several herbal drugs, e.g. senna, a commonly used laxative. As there are only limited data on its clastogenic potential we have investigated its capability to cause chromosomal aberrations in the Chine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924b279af6984c10afbbe500f49f3278
https://doi.org/10.1016/s1383-5718(01)00150-4
https://doi.org/10.1016/s1383-5718(01)00150-4
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 444:421-426
In previous studies, an analytically well-defined senna extract, commonly used as a laxative, gave positive responses in vitro in the Ames test and in the CHO assay. Therefore, the objective of this study was to investigate the genotoxic activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f491ae7ae91ef1ca0b310190c9b14d95
https://doi.org/10.1016/s1383-5718(99)00115-1
https://doi.org/10.1016/s1383-5718(99)00115-1
Publikováno v:
Mutation Research/Genetic Toxicology. 367:123-133
The present in vitro and in vivo experiments were undertaken to clarify the genotoxic potential of the hydroxyanthrachinone aloeemodin which can be found in different plant derived products for therapy of constipation. The results demonstrate that al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70ca31800b3acadb3276c7ddf552d3a
https://doi.org/10.1016/0165-1218(95)00084-4
https://doi.org/10.1016/0165-1218(95)00084-4
Publikováno v:
Nephrology Dialysis Transplantation. 11:55-62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f65590e2cb6daac8c29042a5bbc4d04
https://doi.org/10.1093/oxfordjournals.ndt.a027066
https://doi.org/10.1093/oxfordjournals.ndt.a027066
Autor:
U. Mengs, C. D. Stotzem
Publikováno v:
Archives of Toxicology. 67:307-311
The nephrotoxic action of aristolochic acid (AA) was investigated in female Wistar rats given single doses of 10, 50 or 100 mg/kg by gastric tube. Renal lesions developed within 3 days, the effect being dose-dependent. Histologically, there was evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c96ec77b570a3fd33d122c0b7962be
https://doi.org/10.1007/bf01973700
https://doi.org/10.1007/bf01973700
Publikováno v:
Pharmacology. 47:187-195
Experimental studies indicate that laxatives may induce epithelial damage. In addition, some laxatives induce the release of prostaglandins. Epithelial cell damage and release of prostaglandins are two pathways by which epithelial cell proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5accb5b6f12d9285a7eb9e80bdc90a9
https://doi.org/10.1159/000139858
https://doi.org/10.1159/000139858
Publikováno v:
Zeitschrift für Phytotherapie. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c5fbc1b251f1dcdbf410e59f267bcc4
https://doi.org/10.1055/s-2006-954889
https://doi.org/10.1055/s-2006-954889
Publikováno v:
Anticancer research. 26(2B)
The objective of this randomised, multicentre, double-blind clinical trial was to investigate the impact of PS76A2, an aqueous mistletoe extract standardised to mistletoe lectins, on quality of life (QoL) in breast cancer patients. A total of 352 pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::754a715a96da78ad7a6f233ed7346b98
https://pubmed.ncbi.nlm.nih.gov/16619567
https://pubmed.ncbi.nlm.nih.gov/16619567
Publikováno v:
Anticancer research. 24(2C)
Patients with breast cancer receiving adjuvant chemotherapy frequently suffer from a restricted quality of life (QoL) due to the side-effects of chemotherapy and the consequences of coping with the diagnosis. Therefore, the objective of this clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f205a6f474bb5a4af544db61ef8bdc0
https://pubmed.ncbi.nlm.nih.gov/15154663
https://pubmed.ncbi.nlm.nih.gov/15154663