Zobrazeno 1 - 10
of 43
pro vyhledávání: '"U. Linzner"'
Autor:
Marianne T. Spanner, Michael Rosemann, Walter A. Müller, Michael J. Atkinson, Wolfgang Gössner, U. Linzner
Publikováno v:
Radiat. Res. 164, 230-233 (2005)
Incorporation of bone-seeking, alpha-particle-emitting, heavy-metal radionuclides dramatically increases the incidence of osteosarcoma in humans and experimental animals. The accumulation of these radionuclides within the mineral phase of the bone ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2068cdc75cb26ee1d333bb9a2365df6
https://pubmed.ncbi.nlm.nih.gov/16038594
https://pubmed.ncbi.nlm.nih.gov/16038594
Publikováno v:
Radiat. Res. 138, 415-422 (1994)
Bone sarcomas may be induced throughout the skeleton (systemic) in mice by relatively low internal alpha-particle doses that are distributed over the whole skeleton. The induction of local (periosteal) bone sarcomas after paratibial deposition of ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1dd65ad27b1fd73edba881bd96d3a1
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=27604
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=27604
Autor:
Michael Silbermann, Volker Erfle, U. Linzner, Jörg Schmidt, Erella Livne, Arne Luz, Kathrin Heermeier
Publikováno v:
Radiation and environmental biophysics. 33(1)
Cartilage tissue from embryonic mice which undergoes osteogenic differentiation during in vitro cultivation was used to study the effect of osteosarcomagenic doses of alpha-irradiation and bone-tumor-inducing retroviruses on proliferation and phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404002f944565c492119804c077a027a
https://pubmed.ncbi.nlm.nih.gov/8202594
https://pubmed.ncbi.nlm.nih.gov/8202594
Autor:
A. Luz, W. A. Muller, U. Linzner, P. G. Strau�, J. Schmidt, K. M�ller, M. J. Atkinson, A. B. Murray, W. G�ssner, V. Erfle, H. H�fler
Publikováno v:
Radiation and environmental biophysics. 30(3)
Temporally-limited internal irradiation after incorporation of short-lived bone-seeking radionuclides is a useful experimental tool for the investigation of extrinsic and intrinsic factors which modify the dose dependence of bone tumor risk. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1b9b71d61a6959969823bb8e4caac9
https://pubmed.ncbi.nlm.nih.gov/1924711
https://pubmed.ncbi.nlm.nih.gov/1924711
Publikováno v:
Health physics. 59(3)
Internal doses from the short-lived alpha-emitter 22Ra were given to 4-wk-old female mice. One group of about 300 animals received a single injection of 18.5 kBq 22Ra kg-1 body weight, corresponding to a mean skeletal alpha dose of 0.15 Gy. A second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f91cb5c961ee164c3b46ff408ce7021
https://pubmed.ncbi.nlm.nih.gov/2394588
https://pubmed.ncbi.nlm.nih.gov/2394588
Publikováno v:
Radiation research. 121(1)
The effect of injection of 1.85 kBq/kg of the long-lived radionuclide 227Ac on the induction of osteosarcomas in female NMRI mice by different dose levels (18.5, 74, and 185 kBq/kg) of the short-lived radionuclide 227Th was investigated. The highest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebc8c152130771afdaca653ba6df3689
https://pubmed.ncbi.nlm.nih.gov/2300664
https://pubmed.ncbi.nlm.nih.gov/2300664
Publikováno v:
Radiation Research. 121:14
The effect of injection of 1.85 kBq/kg of the long-lived radionuclide {sup 227}Ac on the induction of osteosarcomas in female NMRI mice by different dose levels (18.5, 74, and 185 kBq/kg) of the short-lived radionuclide {sup 227}Th was investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e62509bef73643d31e027a4b782c13
https://doi.org/10.2307/3577558
https://doi.org/10.2307/3577558
Publikováno v:
Radiation and Environmental Biophysics. 18:1-11
The rare earth radionuclides 177 Lu and 153Sm were administered as single i.p. injections in NMRI mice. Lu was deposited principally (up to 60%) in the skeleton if the quantity of stable carrier was low. Increase of stable carrier enhanced deposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d5a93ec29cc9c8d0ec86ddeac7c789
https://doi.org/10.1007/bf01324368
https://doi.org/10.1007/bf01324368
Publikováno v:
Radiation and Environmental Biophysics. 23:113-115
Combined incorporation of different bone seekers can result in additive and more than additive effect concerning the incidence of bone tumours, provided that the initial dose rate was not too high. According to the multistage theory of carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b19bfc3e4aea62d680f09c3f8ae425
https://doi.org/10.1007/bf01213737
https://doi.org/10.1007/bf01213737
Publikováno v:
International journal of nuclear medicine and biology. 5(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9853aede5984cecc5bcaa635da92e826
https://pubmed.ncbi.nlm.nih.gov/659057
https://pubmed.ncbi.nlm.nih.gov/659057