Zobrazeno 1 - 10
of 72
pro vyhledávání: '"U. Laudenbach"'
Publikováno v:
Toxicology Letters. 188:137-141
One of the most frequently misused steroid precursors (prohormones) is 19-norandrostenedione (estr-4-ene-3,17-dione, NOR). Recently we have show that NOR stimulates skeletal muscle growth after s.c. administration in a highly selective manner but exh
Publikováno v:
Toxicology Letters. 184:198-203
Administration of the isoflavone genistein (GEN) has been described to result in bone protection but also to induce uterotrophic responses. To compare bone protective effects of GEN with an isoflavone-rich diet (IRD) and to further elucidate molecula
Autor:
Patrick Diel, B. Schleipen, T. Hertrampf, M. Velders, U. Laudenbach, Karl Heinrich Fritzemeier
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2008, 291 (1-2), pp.104. ⟨10.1016/j.mce.2008.03.003⟩
Molecular and Cellular Endocrinology, Elsevier, 2008, 291 (1-2), pp.104. ⟨10.1016/j.mce.2008.03.003⟩
To further elucidate the processes involved in the physiology of bone-protection by estrogens, ovariectomized (OVX) rats were treated subcutaneously with 17beta-estradiol (E(2)), the ERalpha-specific agonist (16alpha-LE2) and the ERbeta-specific agon
Publikováno v:
British Journal of Pharmacology. 153:1432-1437
Background and purpose: Studies with oestrogen receptorα (ERα)- and ERβ-selective compounds have already shown that the effects of 17β-estradiol (E2) on body weight, movement drive and bone-protection are mediated via ERα. This study was based o
Autor:
LA Skaltsounis, ME Sakavitsi, P. Diel, Maria Halabalaki, U Laudenbach-Leschowski, ST Ngueu, Job Tchoumtchoua, Dieudonné Njamen
Publikováno v:
Planta Medica. 81
17β-Hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties
Autor:
Hans Geyer, Mario Thevis, Matthias Kamber, Wilhelm Schänzer, Patrick Diel, G. Vollmer, U. Laudenbach-Leschowsky, Oliver Zierau, A. Friedel
Publikováno v:
Toxicology Letters. 165:149-155
Since the begining of the year 2005, the use of steroid precursors (prohormones) is illegal in the United States; nevertheless, there is still an enormous abuse of such substances. One of the most frequently misused steroids, often declared to be a p
Autor:
Gisela H. Degen, Ana Laura Di Virgilio, Abdel Ait Kaid, J. Seibel, U. Laudenbach-Leschowsky, Patrick Diel, T. Hertrampf
Publikováno v:
Planta Medica. 72:484-487
Reduced estrogen levels occurring during menopause in woman are accompanied by a variety of disorders, e. g., hot flushes, depressions, osteoporosis, increase of body weight, and reduced movement drive. In this study we investigated the combined effe
Publikováno v:
Molecular and Cellular Endocrinology. 243:51-57
Cyclooxygenase 2 (Cox-2), an enzyme involved in prostaglandin production, is a key player in the development of pathologic changes, such as colorectal cancer, arteriosclerosis and thrombosis. In this study, we investigated the effects of estrogens, s
Autor:
M. Velders, B. Schleipen, Karl Heinrich Fritzemeier, M. Solzbacher, U. Laudenbach, Patrick Diel
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 120(1)
The age-related decline in ovarian sex hormone production following the onset of menopause alters skeletal muscle metabolic, structural and functional characteristics. The myosin heavy chain (MHC) expression pattern defines skeletal muscle contractio
Autor:
A. Friedel, Matthias Kamber, Mario Thevis, B. Schleipen, Hans Geyer, U. Laudenbach-Leschowsky, W. Schänzer, Patrick Diel, Oliver Zierau, Günter Vollmer
Publikováno v:
Toxicology letters. 177(3)
One of the most frequently misused steroid precursors (prohormones) is 19-norandrostenedione (4-estrene-3,17-dione, NOR), which is, after oral administration, readily metabolised to nortestosterone, also known as nandrolone (durabolin). In this study