Výsledky vyhledávání - "U. Langsenlehner"

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The Role of Radiation Therapy after Incomplete Resection of Penile Cancer

Autor: Tanja Langsenlehner, Ulrike Prettenhofer, Karin S. Kapp, Ramona Mayer, U. Langsenlehner, Karl Pummer, Franz Quehenberger

Publikováno v: Strahlentherapie und Onkologie. 184:359-363

To retrospectively assess the outcome in patients treated with adjuvant radiotherapy for penile cancer. Between 1987 and 2006, 24 patients (median age, 62.7 years; range, 35.5–90.4 years) with squamous cell carcinoma of the penis (T1, n = 10; T2, n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c86669acf101dc962e934a72bef1125
https://doi.org/10.1007/s00066-008-1818-2

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The Glu228Ala polymorphism in the ligand binding domain of death receptor 4 is associated with increased risk for prostate cancer metastases

Autor: U. Langsenlehner, Günter Hofmann, Karl Pummer, Peter Krippl, Wilfried Renner, Heimo Clar, Ramona Mayer, Tanja Langsenlehner, Karin S. Kapp

Publikováno v: The Prostate. 68:264-268

Background Death receptor 4, encoded by the TNFRSF10A gene, is an important mediator of apoptosis and its dysfunction may be related to cancer development and distant tumor spread. A single nucleotide polymorphism in TNFRSF10A (Glu228Ala, rs20576) wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4074f6d109b4b941e48760c96ee24b
https://doi.org/10.1002/pros.20682

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Common single nucleotide polymorphisms in the vascular endothelial growth factor gene and colorectal cancer risk

Autor: Peter Krippl, Tanja Langsenlehner, Heimo Clar, Guenter Hofmann, B. Yazdani-Biuki, Wilfried Renner, U. Langsenlehner, Martin Wehrschuetz, Hellmut Samonigg, Armin Gerger

Publikováno v: Journal of Cancer Research and Clinical Oncology. 134:591-595

Tumor growth requires the formation of new blood vessels, a phenomenon known as angiogenesis. The most important regulator of angiogenesis is vascular endothelial growth factor (VEGF). Several common polymorphisms in the VEGF-gene have been associate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d89b850c01892e62579226375503d0
https://doi.org/10.1007/s00432-007-0322-x

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The LCT 13910 C/T polymorphism as a risk factor for osteoporosis, has no impact on metastatic bone disease in breast cancer

Autor: Heimo Clar, Tanja Langsenlehner, U. Langsenlehner, Guenter Hofmann, Wilfried Renner, Andreas Leithner, B. Yazdani-Biuki, Reinhard Windhager, Peter Krippl, V. Clar, Gerald Gruber

Publikováno v: Breast Cancer Research and Treatment. 112:363-365

To the editorThe most common skeletal complication of breast can-cer is bone metastasis, which occurs in 80% of patientswith advanced disease [1, 2].The maintenance of skeletal integrity in a healthyindividual requires a balanced bone remodeling. Ost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0730e8a5c7c7135d9b5bdd0e5dc6e50
https://doi.org/10.1007/s10549-007-9863-6

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Association of genetic variants in VEGF-A with clinical recurrence in prostate cancer patients treated with definitive radiotherapy

Autor: Eva-Maria Thurner, U. Langsenlehner, Karin S. Kapp, Wilfried Renner, Armin Gerger, Tanja Langsenlehner

Publikováno v: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 190(4)

Vascular endothelial growth factor-A (VEGF-A), a key regulator of tumor-induced angiogenesis, is critical for tumor growth and metastasization. The goal of the present study was to evaluate the prognostic value of VEGF single nucleotide polymorphisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359cb9e2513013fa282fdc4446f15da8
https://pubmed.ncbi.nlm.nih.gov/24435801

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Association of genetic variants in apoptosis genes FAS and FASL with radiation-induced late toxicity after prostate cancer radiotherapy

Autor: Tanja Langsenlehner, Karin S. Kapp, Eva-Maria Thurner, S. Krenn-Pilko, U. Langsenlehner, Armin Gerger, Wilfried Renner

Publikováno v: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 190(3)

Fas ligand (FASL) triggers apoptotic cell death by cross-linking with its receptor FAS, and after irradiation, expression of FAS and FASL is increased. In the present study, we investigated the association between common polymorphisms in the genes fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece0c3ebdc78913d0f1187a095a47967
https://pubmed.ncbi.nlm.nih.gov/24424626

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CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations

Autor: P Krippl, M-T M Lee, Alan H.B. Wu, E Haschke-Becher, Vera J. Suman, Yusuke Nakamura, R Ferraldeschi, Teri E. Klein, U Hamann, Werner Schroth, M Schmidt, Christine B. Ambrosone, Julia C. Stingl, Wendy Lorizio, Richard M. Weinshilboum, Gary Zirpoli, Michel Eichelbaum, JN Ingle, Michael A. Province, P Wegman, Li Gong, Anthony Howell, Matthias W. Beckmann, Virgil Craig Jordan, AM Thompson, Hitoshi Zembutsu, A-S Dieudonné, Russ B. Altman, Ayse Latif, Stefan Winter, S Wingren, J-Y Choi, T Mushiroda, J-G Shin, Matthias Schwab, Matthew M. Ames, Ryan Whaley, David A. Flockhart, Anne T. Nguyen, Lee B. Jordan, Patrick Neven, William G. Newman, U Langsenlehner, Elad Ziv, Colin A. Purdie, Matthew P. Goetz, Joan M. Hebert, Philip R. Quinlan, Peter A. Fasching, Hiltrud Brauch, W Renner, Diether Lambrechts, B-W Park, Kazuma Kiyotani

Publikováno v: Clinical pharmacology and therapeutics. 95(2)

The International Tamoxifen Pharmacogenomics Consortium was established to address the controversy regarding cytochrome P450 2D6 (CYP2D6) status and clinical outcomes in tamoxifen therapy. We performed a meta-analysis on data from 4,973 tamoxifen-tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9c5c363cdd61da0c6ca166b01e5660
https://pubmed.ncbi.nlm.nih.gov/25056391

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Integrin alpha-2 and beta-3 gene polymorphisms and colorectal cancer risk

Autor: Armin Gerger, Hellmut Samonigg, U. Langsenlehner, Thomas C. Wascher, Peter Krippl, Wilfried Renner, Günter Hofmann, Martin Wehrschütz, Werner Weitzer

Publikováno v: International journal of colorectal disease. 24(2)

Integrins such as alpha(2)beta(1), alpha(IIb)beta(3), and alpha(v)beta(3) have been suggested as key players for cancer development and progression. Several polymorphisms affecting these molecules, two in integrin alpha(2) (ITGA2 807CT and 1648GA) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec6ac6b887439b0695edbe5e2061ce4
https://pubmed.ncbi.nlm.nih.gov/18836731

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