Zobrazeno 1 - 10
of 63
pro vyhledávání: '"U. J. Lewis"'
Publikováno v:
Experimental Biology and Medicine. 197:409-415
Mammalian and avian growth hormones (GH) (pituitary derived or biosynthetic) exert two effects on chicken adipose tissue explants in vitro. They (i) increase the basal rate of glycerol release a lipolytic effect) and (ii) inhibit glucagon-stimulated
Publikováno v:
Acta Paediatrica. 83:29-31
Publikováno v:
Endocrinology. 137(1)
Human GH (hGH) fragments 1-43 and 44-191 have potent in vivo effects on glucose homeostasis in rodents but cannot stimulate body growth. To assess the in vitro bioactivity of these hGH fragments we tested their activity against GH-responsive FDC-P1 c
Publikováno v:
Journal of Biological Chemistry. 253:2679-2687
Publikováno v:
Acta Endocrinologica. 98:8-13
Three pituitary adenomas obtained from patients with acromegaly were maintained in organ explant culture for a period of 12 days in a defined culture medium. Lyophilized culture medium from each was then examined by electrophoresis to determine which
Publikováno v:
Endocrinologia Japonica. 34:73-85
1. The hGH20K variant accounts for 10-15% of the hGH in the pituitary gland and is, therefore, the second most abundant hormone in the gland.2. Although no specific RIA exists for hGH20K, which must be measured by a combination of electrophoretic and
Publikováno v:
Diabetologia. 15:129-132
Insulin responses to clinical grade human growth hormone (hGH), intact hGH, naturally occurring diabetogenic substance (NDS), and subtilisin cleaved forms of hGH (S1 and S3) were studied using hypophysectomized rat pancreatic islets. While clinical g
Publikováno v:
Journal of Biological Chemistry. 252:3697-3702
Publikováno v:
Endocrinology. 118:2588-2593
Recent reports describing a direct stimulation by GH of bone and cartilage growth led us to compare the in vitro mitogenic effects of highly purified human GH and PRL and two pituitary-derived growth factors in rabbit articular chondrocytes. These pr
Autor:
U. J. Lewis
Publikováno v:
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology. 1:423-435
The purification of prolactin is simplified by the strong binding of the hormone to pituitary tissue. An extreme alkaline or acidic pH is required to effectively extract prolactin and this provides a convenient way of removing a large number of serum