Zobrazeno 1 - 10
of 55
pro vyhledávání: '"U. I. Walther"'
Publikováno v:
Pharmacopsychiatry. 49:76-78
In this article a case of carbamazepine overdose is reported. It is common to use immuno-based methods in the field of therapeutic drug monitoring but it might be difficult to adapt such values to toxicological cases. For carbamazepine overdoses it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8282ba6649e6048379c96bea88294bad
https://doi.org/10.1055/s-0035-1569268
https://doi.org/10.1055/s-0035-1569268
Publikováno v:
Biomaterials. 31:818-823
Previous in vivo studies have shown that the comonomers triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA) from dental materials can be metabolised to CO(2) by two postulated pathways: an epoxide and a valine pathway. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e635249b650c9ea35b0a7be50e2ca3
https://doi.org/10.1016/j.biomaterials.2009.09.097
https://doi.org/10.1016/j.biomaterials.2009.09.097
Autor:
Regine Stets, U. I. Walther
Publikováno v:
Toxicology. 256:48-52
In previous experiments an increase in zinc-mediated toxicity was found after pretreatment of alveolar epithelial type II-like cells with glucocorticoids. In this work toxicity of two peroxides (tertiary butyl hydroperoxide [tBHP], hydrogene peroxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38be22436d88da9c4bbeb296a58a7ef
https://doi.org/10.1016/j.tox.2008.11.001
https://doi.org/10.1016/j.tox.2008.11.001
Publikováno v:
Biological Trace Element Research. 122:216-228
Zinc toxicity has been linked to cellular glutathione: A decrease in glutathione is followed by an increase in zinc-mediated toxicity. The question arises whether an increase in glutathione synthesis might decrease zinc-mediated cytotoxicity. We incu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315e2d16b634ff7d6ca19cab0171cc79
https://doi.org/10.1007/s12011-007-8072-9
https://doi.org/10.1007/s12011-007-8072-9
Publikováno v:
Biological Trace Element Research. 102:091-104
Zinc-mediated cytotoxicity is recognized, at least in part, by a decrease of reduced glutathione (GSH) and an increase in the oxidized form of glutathione (GSSG). Doxorubicin is a common inducer of multidrug-resistance-associated proteins and such pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441c48a66b644cb4d2277bcfbcc1b6ec
https://doi.org/10.1385/bter:102:1-3:091
https://doi.org/10.1385/bter:102:1-3:091
Publikováno v:
Archives of Toxicology. 77:131-137
Cellular reduced glutathione (GSH) levels have been identified as an essential determinant in zinc-induced cytotoxicity. However, cytotoxic effects of zinc have also been observed without depletion of GSH stores. In a previous study, the intracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f628a18a0f227ab3592777ccffbc5986
https://doi.org/10.1007/s00204-002-0421-z
https://doi.org/10.1007/s00204-002-0421-z
Autor:
Kai Kehe, Wolfgang Spahl, Franz-Xaver Reichl, U. I. Walther, Klaus Gempel, Reinhard Hickel, Karl-Heinz Kunzelmann, Jürgen Durner, Wyatt R. Hume, Bernhard Liebl
Publikováno v:
Dental Materials. 18:581-589
The resin monomer triethyleneglycoldimethacrylate (TEGDMA) is used as a diluent in many resin-based bonding, cementing and direct tooth filling materials.In the present study the uptake and the clearance of 14C-TEGDMA applied via different routes wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e34fcac6dbee2c75db46dbeca6acdbc
https://doi.org/10.1016/s0109-5641(01)00094-x
https://doi.org/10.1016/s0109-5641(01)00094-x
Autor:
Franz-Xaver Reichl, Kai Kehe, M. Nilius, U. I. Walther, S. C. Walther, Reinhard Hickel, Bernhard Liebl
Publikováno v:
Journal of Biomedical Materials Research. 63:643-649
Various ingredients of dental materials and related compounds were tested for cytotoxicity in two alveolar epithelial cell lines (L2 and A549 cells). Release of lactate dehydrogenase (LDH) from cells was measured after incubation with the test substa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24810e6f98ee6e86123615b57857c2f
https://doi.org/10.1002/jbm.10384
https://doi.org/10.1002/jbm.10384
Publikováno v:
Archives of Toxicology. 75:388-394
Zinc-mediated toxicity has been linked to cellular glutathione (GSH) contents. In this study, effects of zinc on cellular GSH content, glutathione reductase (GR) activity, and GSH synthesis were investigated. In all cell lines tested, decreases in ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bb8dd6920a412800f24fa90abdec79
https://doi.org/10.1007/s002040100250
https://doi.org/10.1007/s002040100250
Autor:
H. Kreppel, Jürgen Durner, G.W.H. Moes, Karl-Heinz Kunzelmann, Anahid Jewett, Wyatt R. Hume, U. I. Walther, M.Y. Wang, Kai Kehe, W. Spahl, Reinhard Hickel, Franz-Xaver Reichl, Wolfgang Forth
Publikováno v:
Scopus-Elsevier
The monomer triethyleneglycoldimethacrylate (TEGDMA) is used as a diluent in many resin-based dental materials. It was previously shown in vitro that TEGDMA was released into the adjacent biophase from such materials during the first days after place
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e2084aa900745580d28f5e7214d4be
https://doi.org/10.1177/00220345010800050501
https://doi.org/10.1177/00220345010800050501