Zobrazeno 1 - 10
of 59
pro vyhledávání: '"U. Hacker-Klom"'
Publikováno v:
Andrologia. 17:389-394
Summary: Flow cytometric measurements of the cellular DNA contents of 16 testicular biopsies of 15 patients with maldescended testes were performed. 2 patients were children. 11 patients of pubescent or adult age had no haploid germ cells in the tiss
Autor:
Elke Pascher, Erhard Severin, U. Hacker-Klom, Normann Willich, Burkhard Greve, Niels Wedemeyer, Joachim Kienast, Gerda Silling, Wolfgang Göhde
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 64:242-250
Purpose: An escalation in standard irradiation dose ensuring improved local tumor control is estimated, but this strategy would require the exclusion of the most sensitive individuals from treatment. Therefore, fast and reliable assays for prediction
Autor:
Erhard Severin, Burkhard Greve, U. Hacker-Klom, Niels Wedemeyer, Wolfgang Köhnlein, Wolfgang Göhde, Daniela Uthe, Dagmar Denklau, Thomas Pötter
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 473:73-84
Determination of the genotoxic effects of ionizing radiation, especially at low-doses, is of great importance for risk assessment, e.g. in radiological diagnostics. The human-hamster hybrid A L cell line has been shown previously to be a well-suited
Publikováno v:
Radiation Research. 154:667-672
Hacker-Klom, U. B., Kohnlein, W. and Gohde, W. Effects of Single and Split Doses of Cobalt-60 Gamma Rays and 14 MeV Neutrons on Mouse Stem Cell Spermatogonia. The long-term effects of ionizing radiation on male gonads may be the result of damage to s
Publikováno v:
Radiation Research. 153:734-742
Hacker-Klom, U. B., Kohnlein, W., Kronholz, H. L. and Gohde, W. The Relative Biological Effectiveness of Low Doses of 14 MeV Neutrons in Steady-State Murine Spermatogenesis as Determined by Flow Cytometry. The relative biological effectiveness of 14
Autor:
U. Hacker-Klom
Publikováno v:
Zeitschrift für Naturforschung C. 50:303-310
The dependence of spermatogenesis function on murine age shall be investigated. Thus, testicular samples of at least 10 NMRI mice per group aged 0 to 26 months are analysed by flow cytometry after staining the DNA with DAPI. The aim of this study is
Autor:
U. Hacker-Klom
Publikováno v:
Zeitschrift für Naturforschung C. 49:522-525
We analysed testicular samples of NMRI mice every 2 h of a day in order to determine whether there is a circadian rhythm in spermatogenetic activity. We used flow cytometry after staining the DNA with DAPI. The highest proportion of DNA synthesizing
Publikováno v:
Cytometry. 11:586-594
Sperm head cytometry provides a useful assay for the detection of radiation-induced damage in mouse germ cells. Exposure of the gonads to radiation is known to lead to an increase of diploid and higher polyploid sperm and of sperm with head shape abn
Publikováno v:
Human reproduction (Oxford, England). 14(10)
The aim of this study was the evaluation of DNA flow cytometry for the analysis of male infertility. 171 ejaculates from 155 patients with fertility problems were analysed by flow cytometry and by conventional microscopical procedures. Using flow cyt
Autor:
Stefan Schlatt, Luca Foppiani, G. F. Weinbauer, Eberhard Nieschlag, U Hacker-Klom, Manuela Simoni
Publikováno v:
The Journal of endocrinology. 162(3)
This study evaluated the effect of bilateral testicular irradiation (2 Gy) on reproductive hormones, testicular volume (TV) and sperm parameters in six adult cynomolgus monkeys. Hormone levels (FSH, inhibin B and testosterone (T)) were determined to