Zobrazeno 1 - 10
of 56
pro vyhledávání: '"U. Frediani"'
Autor:
Annalisa Tanini, Rosaria Casano, Maria Luisa Brandi, Susanna Benvenuti, U. Frediani, S. Bianchi, L. Bufalino, Laura Masi, Mario Serio
Publikováno v:
Journal of Bone and Mineral Research. 6:987-996
Protective effects of ipriflavone, an isoflavone derivative, in osteoporosis are believed to be caused by the inhibitory action on bone resorption. A direct effect of ipriflavone on bone formation is as yet unknown. Ipriflavone and four of its metabo
Heterogeneity of Binding Sites and Bioeffects of Raloxifene on the Human Leukemic Cell Line FLG 29.1
Autor:
U. Frediani, Valentina Martineti, Maria Luisa Brandi, Susanna Benvenuti, Sandra Zecchi, Lucia Formigli, Francesca Gori, Gianna Fiorelli
Publikováno v:
Biochemical and Biophysical Research Communications. 240:573-579
The benzothiophene divarative raloxifene is known to mimic estrogen in human bone remodeling. To investigate the "in vitro" properties of raloxifene on osteoclast precursors, the human leukemic cell line FLG 29.1, which differentiates toward the oste
Autor:
Luigi Gennari, L. Becherini, Susanna Benvenuti, C. Tosti-Guerra, Maria Luisa Brandi, U. Frediani, Gianna Fiorelli, Annalisa Tanini, Francesca Gori, Francesco Franceschelli
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 59:233-240
Besides functional estrogen receptors, the presence of signalling cell surface binding sites for 17beta-estradiol (17betaE2) has been reported in osteoblast- and osteoclast-like cells, suggesting that 17betaE2 may influence bone remodelling by a dual
Publikováno v:
Journal of Endocrinological Investigation. 19:298-303
Using a clonal line of bovine parathyroid endothelial cells (BPE-1) we defined the presence on these cells of a histamine H2 receptor and characterized its pharmacological properties. Interaction of histamine with its receptor induced an increase of
Autor:
U. Frediani, Gianna Fiorelli, Michael B. Sporn, M. L. Brandi, Ballock Rt, P. A. Bernabei, Lalage M. Wakefield, Laura Masi, Annalisa Tanini, Francesca Gori
Publikováno v:
Journal of Cellular Physiology. 160:482-490
Increasing evidence suggests that transforming growth factor-beta (TGF-beta) is involved in bone formation during remodeling. Using a recently cloned human leukemic cell line (FLG 29.1 cells) we demonstrate that these cells synthesize and secrete TGF
Autor:
U. Frediani, Carlo Gennari, Clara Crescioli, Donato Agnusdei, Maria Luisa Brandi, Annalisa Tanini
Publikováno v:
Calcified Tissue International. 53:312-317
In the present study, we investigated the effects of estrogens on bone endothelial cell metabolism and the presence of estrogen binding sites in the same cells. For these studies, we have used a continuous cell line of clonal bovine bone endothelial
Autor:
Mario Serio, M. L. Brandi, A. Becorpi, C. Tosti-Guerra, O Bartolini, M. L. De Feo, Francesco Franceschelli, U. Frediani, Annalisa Tanini, Clara Crescioli
Publikováno v:
Endocrinology. 133:1759-1766
[125I]Atrial natriuretic peptide (ANP) was used to identify ANP receptors on a clonal line of bovine bone endothelial (BBE) cells. Specific binding of [125I]ANP was saturable and of high affinity. Computer analysis of the equilibrium binding data ind
Publikováno v:
Autoimmunity. 6:239-248
Although an autoimmune pathogenesis for non toxic goiter has been suggested, reports concerning circulating antibodies to TSH receptor structures have been conflicting. Intra thyroid lymphocytes, capable of secreting IgG, have been shown to be involv
Autor:
Mario Serio, Francesco Franceschelli, Francesca Gori, U. Frediani, Valentina Martineti, Annalisa Tanini, Maria Luisa Brandi, Alessandro Franchi, Gianna Fiorelli
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 66(3)
The recent observation that estrogen synthesis occurs in osteoblast-like cells has suggested the aromatase activity as a possible local modulator of bone remodeling in post-menopausal women. To provide further insights into the androstenedione conver
Publikováno v:
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 6(1)
Using a clonal cell line of human osteoclast precursors (FLG 29.1 cells), that after treatment with 12-O-tetradecanoyl phorbol 13-acetate (TPA) show many functional characteristics of osteoclasts, we demonstrated that catecholamines act as inducers o