Zobrazeno 1 - 10
of 238
pro vyhledávání: '"U. Benjamin Kaupp"'
Autor:
Jan N. Hansen, An Gong, Dagmar Wachten, René Pascal, Alex Turpin, Jan F. Jikeli, U. Benjamin Kaupp, Luis Alvarez
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Multifocal imaging suffers from a number of limitations. Here the authors report an open-source 3D reconstruction algorithm to enable label-free tracking of spherical and filamentous structures which they use to characterise fluid flow and flagellar
Externí odkaz:
https://doaj.org/article/6077319b1f614bdbad31c204d6adbb5d
Autor:
Thomas Quast, Karolin Zölzer, Donald Guu, Luis Alvarez, Carsten Küsters, Eva Kiermaier, U. Benjamin Kaupp, Waldemar Kolanus
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Navigation of dendritic cells (DCs) from the site of infection to lymphoid organs is guided by concentration gradients of CCR7 ligands. How cells interpret chemokine gradients and how they couple directional sensing to polarization and persistent che
Externí odkaz:
https://doaj.org/article/de00a3a78d7140b9889d49af08f77127
Autor:
Michelina Kierzek, Parker E Deal, Evan W Miller, Shatanik Mukherjee, Dagmar Wachten, Arnd Baumann, U Benjamin Kaupp, Timo Strünker, Christoph Brenker
Publikováno v:
eLife, Vol 10 (2021)
Fluorescent probes that change their spectral properties upon binding to small biomolecules, ions, or changes in the membrane potential (Vm) are invaluable tools to study cellular signaling pathways. Here, we introduce a novel technique for simultane
Externí odkaz:
https://doaj.org/article/ff6c6b36dc74490c9dc0a6d1e5cee781
Publikováno v:
Trends in Neurosciences. 45:763-776
Cyclic nucleotide-gated (CNG) channels play a central role in rod and cone photoreceptors of the vertebrate retina. In photoreceptors, light triggers a series of biochemical reactions that ultimately close CNG channels and evoke a brief voltage pulse
Autor:
Melanie Balbach, Hussein Hamzeh, Jan F. Jikeli, Christoph Brenker, Christian Schiffer, Jan N. Hansen, Pia Neugebauer, Christian Trötschel, Luca Jovine, Ling Han, Harvey M. Florman, U. Benjamin Kaupp, Timo Strünker, Dagmar Wachten
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mammalian oocytes are enveloped by the zona pellucida (ZP), an extracellular matrix of glycoproteins. In sperm, stimulation with ZP proteins evokes a rapid Ca2+ influx via the sperm-specific, pH-sensitive Ca2+ channel CatSper. However, the physiologi
Externí odkaz:
https://doaj.org/article/87d6e04ca4ce4b2cb1e990ab3f22a423
Autor:
Guglielmo Saggiorato, Luis Alvarez, Jan F. Jikeli, U. Benjamin Kaupp, Gerhard Gompper, Jens Elgeti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The mechanism allowing sperm to steer is not fully understood. The authors find that superposition of two harmonic waves breaks the flagellar beat symmetry temporally rather than spatially, and that this mechanism is enhanced by the sexual hormone pr
Externí odkaz:
https://doaj.org/article/d97db4ce226d4bffbf1df60dbd803fb0
Autor:
U. Benjamin Kaupp, Franz Hofmann, Verena Hammelmann, Stefanie Fenske, Martin Biel, Elvir Becirovic
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Cyclic nucleotide-gated (CNG) channels are responsible for signalling in the primary sensory cells of the vertebrate visual and olfactory systems. CNG channels are voltage-independent cation channels formed as tetramers. Each subunit has 6TM, with th
Autor:
Diane C. A. Barret, Dina Schuster, Matthew J. Rodrigues, Alexander Leitner, Paola Picotti, Gebhard F. X. Schertler, U. Benjamin Kaupp, Volodymyr M. Korkhov, Jacopo Marino
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 120 (15)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Calmodulin (CaM) regulates many ion channels to control calcium entry into cells, and mutations that alter this interaction are linked to fatal diseases. The structural basis of CaM regulation remains largely unexplored. In retinal photoreceptors, Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d559989736b821de9d5ec9185bbd0b1f
Publikováno v:
Nature Structural and Molecular Biology
In rod photoreceptors of the retina, the cyclic nucleotide-gated (CNG) channel is composed of three CNGA and one CNGB subunits, and it closes in response to light activation to generate an electrical signal that is conveyed to the brain. Here we repo
Publikováno v:
Journal of Structural Biology, 214 (1)
Journal of Structural Biology
Journal of Structural Biology
The recently reported structure of the human CNGA1/CNGB1 CNG channel in the open state (Xue et al., 2021a) shows that one CNGA1 and one CNGB1 subunit do not open the central hydrophobic gate completely upon cGMP binding. This is different from what h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51de08a43707aea2c9d771f3cc9474ad