Výsledky vyhledávání - "U. Bamberger"

Expression of the fibroblast activation protein during mouse embryo development

Autor: J, Niedermeyer, P, Garin-Chesa, M, Kriz, F, Hilberg, E, Mueller, U, Bamberger, W J, Rettig, A, Schnapp

Publikováno v: The International journal of developmental biology. 45(2)

Human Fibroblast Activation Protein (FAP), a member of the serine prolyl oligopeptidase family, is a type II cell surface glycoprotein that acts as a dual-specificity dipeptidyl-peptidase (DPP) and collagenase in vitro. Its restricted expression patt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::acdf70249ddff7228078287014f36a64
https://pubmed.ncbi.nlm.nih.gov/11330865

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Targeted disruption of mouse fibroblast activation protein

Autor: John Edward Park, H. Püschner, M. Kriz, Wolfgang J. Rettig, M. Mauz, Martin Lenter, Frank Hilberg, Andreas Schnapp, Joachim Niedermeyer, Pilar Garin-Chesa, U. Bamberger, Bruno Viertel

Publikováno v: Molecular and cellular biology. 20(3)

Human fibroblast activation protein (FAP), a member of the serine prolyl oligopeptidase family, is a type II cell surface glycoprotein selectively expressed by fibroblastic cells in areas of active tissue remodeling, such as the embryonic mesenchyme,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e12d615663c0ac4dce3275137c1539
https://pubmed.ncbi.nlm.nih.gov/10629066

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BIBW22 BS, potent multidrug resistance-reversing agent, binds directly to P-glycoprotein and accumulates in drug-resistant cells

Autor: Z, Liu, F, Lheureux, J F, Pouliot, A, Heckel, U, Bamberger, E, Georges

Publikováno v: Molecular pharmacology. 50(3)

The expression of P-glycoprotein (P-gp) in tumor cells causes a multidrug resistance (MDR) phenotype. P-gp has been shown to mediate the transport of structurally dissimilar drugs across the cell membrane in an energy-dependent manner. In this report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4aa8e8290b237bd2c32f6db1080f79b
https://pubmed.ncbi.nlm.nih.gov/8794885

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In Vitro Modulation of Multidrug Resistance by BIBW22BS in Blasts of De Novo or Relapsed or Persistent AML

Autor: A. Heckel, M.E. Scheulen, U. Bamberger, M. Esteban, J. Schröder, Sabine Kasimir-Bauer, S. Seeber

Publikováno v: Acute Leukemias V ISBN: 9783642789090

Drug resistance to chemotherapy is an important factor of treatment failure in acute myeloid leukemia (AML). One type of resistance, the multidrug resistance (MDR), can develop after exposure to certain natural chemotherapeutic agents such as vinca a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1e8100c0adb722346b38af06a811373
https://doi.org/10.1007/978-3-642-78907-6_18

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The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts

Autor: H.M. Pinedo, U. Bamberger, W. J. M. Jansen, C.L. van der Wilt, N. Feller, Epie Boven

Publikováno v: European journal of cancer (Oxford, England : 1990). (13-14)

Dipyridamole is known as a potent inhibitor of facilitated diffusion-mediated nucleoside transport as well as a modulator of ‘classical' multidrug resistance. BIBW22BS, a derivative of dipyridamole, has been found to be 20-to 100-fold more potent i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201607e6ad2f72e13381faac406f174b
https://pubmed.ncbi.nlm.nih.gov/8652262

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Biochemical modulation of 'classical' multidrug resistance by BOBW22BS, a potent derivative of dipyridamole

Autor: Epie Boven, H.M. Pinedo, C. M. Kuiper, U. Bamberger, C. Lincke, A. Heckel, W.J.M. Jansen

Publikováno v: Annals of Oncology, 5, 733-739. Oxford University Press
Jansen, W J M, Pinedo, H M, Kuiper, C M, Lincke, C, Bamberger, U, Heckel, A & Boven, E 1994, ' Biochemical modulation of 'classical' multidrug resistance by BOBW22BS, a potent derivative of dipyridamole ', Annals of Oncology, vol. 5, pp. 733-739 .

Summary Background Modulators of the ‘classical’ multidrug resistance (mdr) phenotype have low efficacy in patients with solid tumors. We analyzed BIBW22BS, 4-[N-(2-hydroxy-2-met-hyl-propyl)-ethanolamino]-2,7-bis(cis-2,6-dimethyl-morpho-lino)- 6-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747fb7270f15a3faae4332b83441caa4
https://research.vumc.nl/en/publications/03c1534c-c5c5-4c96-8c84-0f25334aae3f

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BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport

Autor: H X, Chen, U, Bamberger, A, Heckel, X, Guo, Y C, Cheng

Publikováno v: Cancer research. 53(9)

BIBW 22, a phenylpteridine analogue of dipyridamole (DPM), enhanced vincristine cytotoxicity approximately 10 times more than DPM in a multidrug-resistant (MDR) KB V20C cell line. Using rhodamine 123 accumulation in KB V20C cells as an indicator of M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6123399d303c24d4f691616cc1cab84
https://pubmed.ncbi.nlm.nih.gov/8097671

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Immunogenicity and immunomodulatory activity of bovine surfactant (SF-RI 1)

Autor: U Bamberger, L. Gortner, Frank Pohlandt, P Bartmann

Publikováno v: Acta paediatrica (Oslo, Norway : 1992). 81(5)

Respiratory distress syndrome in preterm infants can be treated successfully by endotracheal administration of a bovine surfactant preparation (SF-RI 1). Before the routine use of xenogenic surfactant preparations can be recommended, their immunogeni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b448dd23f41c188f319fd26bdf87e8d
https://pubmed.ncbi.nlm.nih.gov/1498502

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