Zobrazeno 1 - 10 of 58 pro vyhledávání: '"U-BIOPRED"'
1
The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts
Autor: Hou, R, Ye, G, Cheng, X, Shaw, DE, Bakke, PS, Caruso, M, Dahlen, B, Dahlen, S-E, Fowler, SJ, Horváth, I, Howarth, P, Krug, N, Montuschi, P, Sanak, M, Sandström, T, Auffray, C, De Meulder, B, Sousa, AR, Adcock, IM, Fan Chung, K, Sterk, PJ, Skipp, PJ, Schofield, J, Djukanović, R, U-BIOPRED Study Group
Publikováno v: U-BIOPRED Study Group 2023, ' The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts ', Brain, Behavior, and Immunity, vol. 111, pp. 249-258 . https://doi.org/10.1016/j.bbi.2023.04.011
BACKGROUND: Growing evidence indicates high comorbid anxiety and depression in patients with asthma. However, the mechanisms underlying this comorbid condition remain unclear. The aim of this study was to investigate the role of inflammation in comor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f54e16b71445fe5838b71e25373385
https://publica.fraunhofer.de/handle/publica/442951
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2
Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort
Autor: P. J. Sterk, John H. Riley, Thomas Sandström, Anna Selby, Laurie Pahus, C. Auffray, Ioannis Pandis, Julie Corfield, R. Djukanovic, K. Sun, Massimo Caruso, Jørgen Vestbo, Matthew J. Loza, Andrew J. Simpson, Dominic Burg, I.M. Adcock, S. Bates, Scott Wagers, Ana R. Sousa, J. Corfield, Ariane H. Wagener, René Lutter, Barbro Dahlén, Ratko Djukanovic, G. Praticò, I. Pandis, N. Mores, G. Hedlin, Navin Rao, I. Horváth, Alexander Mazein, B. De Meulder, Richard G. Knowles, John-Olof Thörngren, Wolfgang Seibold, P H Howarth, Victoria M. Goss, Cristina Gómez, Clare S. Murray, Paul Brinkman, Ildiko Horvath, Anthony D. Postle, M. Caruso, Martina Gahlemann, M. Puig Valls, F.K. Chung, P. Montuschi, Dominick E. Shaw, Kai Sun, Aruna T. Bansal, Fahad Alahmadi, Amphun Chaiboonchoe, Graham Roberts, Kian Fan Chung, Yike Guo, H. Ahmed, Thomas Geiser, Klaus Bønnelykke, M. Miralpeix, Simone Hashimoto, Diane Lefaudeux, S.S. Wagers, D. Erzen, B. Thornton, Florian Singer, Louise Fleming, Stephen J. Fowler, Neil Fitch, P. Bakke, Craig E. Wheelock, Nadja Hawwa Vissing, Tim Higenbottam, Jamie Matthews, F. Singer, S.E. Dahlén, Sarah Masefield, Roelinde Middelveld, Jens M. Hohlfeld, Anthony V. D'Amico, Paul Skipp, W.M.C. van Aalderen, Alan J. Knox, Sven-Erik Dahlén, Andrew Bush, A.T. Bansal, Pieter-Paul Hekking, Joost Brandsma, Stewart Bates, L.J. Fleming, Norbert Krug, N. Krug, Magnus Ericsson, J. Riley, P. Powel, Jacek Musiał, Amanda Roberts, Peter J. Sterk, Ian M. Adcock, Pascal Chanez, Cecile T.J. Holweg, F. Baribaud, Stelios Pavlidis, Veit J. Erpenbeck, Z. Weiszhart, C.E. Wheelock, Ralf Sigmund, James P.R. Schofield, Alexander Manta, Andrea Meiser, Susan J. Wilson, Jeanette Bigler, G. Roberts, M. van Geest, Hans Bisgaard, Urs Frey, Michael Boedigheimer, Per Bakke, Chris Compton, Enrica Bucchioni, Paolo Montuschi, David Myles, E.H.D. Bel, Anna James, Elena Formaggio, Anthony Rowe, Dominic E. Shaw, J. Haughney, P. Chanez, A.R. Sousa, S.J. Fowler, K. Fichtner, B. Dahlèn
Publikováno v: U-BIOPRED Study Group 2021, ' Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort ', Chest . https://doi.org/10.1016/j.chest.2021.02.023
Alahmadi, Fahad H; Simpson, Andrew J; Gomez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Wheelock, Craig; Shaw, Dominic E; Fleming, Louise J; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R; Knowles, Richard; Bansal, Aruna T; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; ... (2021). Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort. Chest, 160(1), pp. 53-64. Elsevier 10.1016/j.chest.2021.02.023
Chest
Chest, 2021, 160 (1), pp.53-64. ⟨10.1016/j.chest.2021.02.023⟩
Chest, 160(1), 53-64. American College of Chest Physicians
Background: Although estimates of suboptimal adherence to oral corticosteroids in asthma range from 30% to 50%, no ideal method for measurement exists; the impact of poor adherence in severe asthma is likely to be particularly high. Research Question
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468463af63606145dd36257575147b02
http://www.scopus.com/inward/record.url?scp=85109134627&partnerID=8YFLogxK
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3
Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma
Autor: Woo-Jung Song, Peter J. Sterk, Ian M. Adcock, Kian Fan Chung, Ratko Djukanovic, Peter H. Howarth, Kai Sun, Nazanin Zounemat Kermani, Yusef Badi, Ali Versi, Sven-Erik Dahlén, Yike Guo, Pank Bhavsar
Publikováno v: Respiratory Research, Vol 22, Iss 1, Pp 1-10 (2021)
Respiratory Research
Background Patients with severe asthma may have a greater risk of dying from COVID-19 disease. Angiotensin converting enzyme-2 (ACE2) and the enzyme proteases, transmembrane protease serine 2 (TMPRSS2) and FURIN, are needed for viral attachment and i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123c554c668ece1ab36fbd2c3da197ee
https://doaj.org/article/7e30d9684b8b4228a8ed66b954de553c
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4
Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation
Publikováno v: American journal of respiratory and critical care medicine. 203(1):37-53
Rationale: New approaches are needed to guide personalized treatment of asthma. Objectives: To test if urinary eicosanoid metabolites can direct asthma phenotyping. Methods: Urinary metabolites of prostaglandins (PGs), cysteinyl leukotrienes (CysLTs)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::48220773bad46ce7396d1f48c4404807
https://doi.org/10.1164/rccm.201909-1869oc
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5
eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy
Autor: Yennece W.F. Dagelet, Andrew Bush, Gunilla Hedlin, Stephen J. Fowler, Ratko Djukanovic, Rianne de Vries, Louise Fleming, John H. Riley, Sven-Erik Dahlén, Anne H. Neerincx, Urs Frey, Kian Fan Chung, Clare S. Murray, Peter J. Sterk, Mahmoud I. Abdel-Aziz, Paul Brinkman, Ian M. Adcock, Anke H. Maitland-van der Zee, Simone Hashimoto, Karen Knipping, Florian Singer, Aletta D. Kraneveld, Graham Roberts, Susanne J. H. Vijverberg
Publikováno v: Journal of allergy and clinical immunology, 146(5), 1045-1055. Mosby Inc.
Abdel-Aziz, Mahmoud I; Brinkman, Paul; Vijverberg, Susanne J H; Neerincx, Anne H; de Vries, Rianne; Dagelet, Yennece W F; Riley, John H; Hashimoto, Simone; Chung, Kian Fan; Djukanovic, Ratko; Fleming, Louise J; Murray, Clare S; Frey, Urs; Bush, Andrew; Singer, Florian; Hedlin, Gunilla; Roberts, Graham; Dahlén, Sven-Erik; Adcock, Ian M; Fowler, Stephen J; ... (2020). eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy. Journal of allergy and clinical immunology, 146(5), pp. 1045-1055. Elsevier 10.1016/j.jaci.2020.05.038
U-BIOPRED Study Group 2020, ' eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy ', The Journal of allergy and clinical immunology, vol. 146, no. 5, pp. 1045-1055 . https://doi.org/10.1016/j.jaci.2020.05.038
BACKGROUND: Electronic noses (eNoses) are emerging point-of-care tools that may help in the subphenotyping of chronic respiratory diseases such as asthma.OBJECTIVE: We aimed to investigate whether eNoses can classify atopy in pediatric and adult pati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf51a1ed1030c29bffe2948f0783eec
https://doi.org/10.1016/j.jaci.2020.05.038
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7
Sputum macrophage diversity and activation in asthma: Role of severity and inflammatory phenotype
Autor: Stelios Pavlidis, Philip M. Hansbro, Yusef Badi, Kian Fan Chung, Yike Guo, Ian M. Adcock, Angelica Tiotiu, Nazanin Zounemat Kermani
Publikováno v: Allergy. 76:775-788
BACKGROUND: Macrophages control innate and acquired immunity but their role in severe asthma remains ill-defined. We investigated gene signatures of macrophage subtypes in the sputum of 104 asthmatics and 16 healthy volunteers from the U-BIOPRED coho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8c29368a93924bf28ebcd26515ff36
https://doi.org/10.1111/all.14535
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8
Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort
Autor: Hoda, Uruj, Pavlidis, Stelios, Bansal, Aruna T, Takahashi, Kentaro, Hu, Sile, Ng Kee Kwong, Francois, Rossios, Christos, Sun, Kai, Bhavsar, Pankaj, Loza, Matthew, Baribaud, Frederic, Chanez, Pascal, Fowler, Stephen J, Horvath, Ildiko, Montuschi, Paolo, Singer, Florian, Musial, Jacek, Dahlen, Barbro, Krug, Norbert, Sandstrom, Thomas, Shaw, Dominic E, Lutter, Rene, Fleming, Louise J, Howarth, Peter H, Caruso, Massimo, Sousa, Ana R, Corfield, Julie, Auffray, Charles, De Meulder, Bertrand, Lefaudeux, Diane, Dahlen, Sven-Erik, Djukanovic, Ratko, Sterk, Peter J, Guo, Yike, Adcock, Ian M, Chung, Kian Fan
Publikováno v: Hoda, Uruj; Pavlidis, Stelios; Bansal, Aruna T; Takahashi, Kentaro; Hu, Sile; Ng Kee Kwong, Francois; Rossios, Christos; Sun, Kai; Bhavsar, Pankaj; Loza, Matthew; Baribaud, Frederic; Chanez, Pascal; Fowler, Stephen J; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlen, Barbro; Krug, Norbert; Sandstrom, Thomas; ... (2022). Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort. Clinical and translational medicine, 12(4), e816. 10.1002/ctm2.816
Clinical and translational medicine, 12(4):10.1002/ctm2.816. Springer Verlag
U-BIOPRED Study Group 2022, ' Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort ', Clinical and Translational Medicine, vol. 12, no. 4, e816 . https://doi.org/10.1002/ctm2.816
BACKGROUND: Exacerbation-prone asthma is a feature of severe disease. However, the basis for its persistency remains unclear.OBJECTIVES: To determine the clinical and transcriptomic features of frequent exacerbators (FEs) and persistent FEs (PFEs) in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a4337242a59bba530f5edcb3f85625
https://pubmed.ncbi.nlm.nih.gov/36149782
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10
Mapping atopic dermatitis and anti–IL-22 response signatures to type 2–low severe neutrophilic asthma
Autor: Ana B. Pavel, Norbert Krug, Dominick E. Shaw, Florian Singer, Peter H. Howarth, Stewart Bates, SE Dahlen, Louise Fleming, Johan Kolmert, Kian Fan Chung, Nazanin Zounemat Kermani, John H. Riley, Stephen J. Fowler, Craig E. Wheelock, Yusef Badi, Stelios Pavlidis, Massimo Caruso, Yike Guo, Anke H. Maitland-van der Zee, Kjell Alving, Ildiko Horvath, Peter J. Sterk, Ian M. Adcock, Pascal Chanez, Sally Worsley, Marek Sanak, Ratko Djukanovic, Per Bakke, Paolo Montuschi, Emma Guttman-Yassky, Richard G. Knowles, Urs Frey, Annelie F. Behndig, Mohib Uddin, Graham T. Roberts
Publikováno v: Journal of allergy and clinical immunology, 149(1), 89-101. Mosby Inc.
Badi, Yusef Eamon; Pavel, Ana B; Pavlidis, Stelios; Riley, John H; Bates, Stewart; Kermani, Nazanin Zounemat; Knowles, Richard; Kolmert, Johan; Wheelock, Craig E; Worsley, Sally; Uddin, Mohib; Alving, Kjell; Bakke, Per S; Behndig, Annelie; Caruso, Massimo; Chanez, Pascal; Fleming, Louise J; Fowler, Stephen J; Frey, Urs; Howarth, Peter; ... (2022). Mapping atopic dermatitis and anti-IL-22 response signatures to Type 2-low severe neutrophilic asthma. Journal of allergy and clinical immunology, 149(1), pp. 89-101. Elsevier 10.1016/j.jaci.2021.04.010
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, 2022, 149 (1), pp.89-101. ⟨10.1016/j.jaci.2021.04.010⟩
U-BIOPRED Study Group 2021, ' Mapping atopic dermatitis and anti-IL-22 response signatures to type 2-low severe neutrophilic asthma ', The Journal of allergy and clinical immunology . https://doi.org/10.1016/j.jaci.2021.04.010
Background: Transcriptomic changes in patients who respond clinically to biological therapies may identify responses in other tissues or diseases. Objective: We sought to determine whether a disease signature identified in atopic dermatitis (AD) is s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6225f583d12c38900493ddc19f22a0f
https://pure.amc.nl/en/publications/mapping-atopic-dermatitis-and-antiil22-response-signatures-to-type-2low-severe-neutrophilic-asthma(2ad79baf-37e4-4dc7-9c5b-d6d4cd3eab27).html
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