Zobrazeno 1 - 10
of 122
pro vyhledávání: '"U-50488"'
Publikováno v:
Research Results in Pharmacology, Vol 9, Iss 4, Pp 21-29 (2023)
Introduction: Among the various receptor systems in the brain, the opioid receptors have been the subject of extensive research due to their integral role in pain modulation, reward processing, and emotional regulation. The kappa-opioid receptor (KOR
Externí odkaz:
https://doaj.org/article/c29d14f3fe5c4793ba02339d70e8e507
Akademický článek
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Autor:
Matthew L. Banks, Kaycee E. Faunce
Publikováno v:
Experimental and Clinical Psychopharmacology. 28:44-54
Repeated drug administration results in sensitization, tolerance, or no change in subsequent drug-induced alterations of motivated behaviors, such as intracranial self-stimulation (ICSS). For example, repeated mu-opioid agonist administration results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f323ec824b771e361249b706a87f34
https://doi.org/10.1037/pha0000287
https://doi.org/10.1037/pha0000287
Akademický článek
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Autor:
Mark R. Nilges, Ashton Jeremy Friend, Laura Lynn Erwin, Abdurrahman Jeremy Aslan, Peter J. Winsauer, William L. Smith
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6fa10421c66da4da270e502a03d4857
https://doi.org/10.1096/fasebj.2020.34.s1.06930
https://doi.org/10.1096/fasebj.2020.34.s1.06930
Autor:
Jun Zhang, Stephen P.J. Fancy, Jonah R. Chan, Nian Yang, Feng Mei, Yi Wu, Xing Gao, Lan Xiao, Guang-Qiang Pan, Nan-Xing Huang, Yu-Jian Yang, Fei Wang, Hongli Li, Shubao Liu, Xianjun Chen, Zhi Liu, Tao Li
Publikováno v:
Neuron, vol 99, iss 4
Summary To address the significance of enhancing myelination for functional recovery after white matter injury (WMI) in preterm infants, we characterized hypomyelination associated with chronic hypoxia and identified structural and functional deficit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a432897ca5c646301c9e695bc8ed19
https://escholarship.org/uc/item/06g2d27w
https://escholarship.org/uc/item/06g2d27w
Autor:
Kevin Cho, Liza Chacko, Zubair M Amin, Saeed K Alzghari, Kerry Anne Rambaran, Steven W. Fleming
Publikováno v:
Cureus
Increased experimentation with easily accessible synthetic opioids is posing a hazard to the public. We discuss one such synthetic opioid, U-50488. Much is unknown about U-50488; however, due to its structural similarity to U-47700, there is possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50af2abb4f08ea8370a5f8f978a882b4
https://doi.org/10.7759/cureus.1914
https://doi.org/10.7759/cureus.1914
Akademický článek
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Autor:
Adriaan P. IJzerman
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 112:169-173
In the last decade, much interest has been shown in the development of agonists selective for the κ-opioid receptor, which are potentially useful as analgesics with fewer side effects than morphine. The prototype drug is the benzeneacetamide U 50488
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14b8c0c3aac77af815ddcefd3e286cd3
https://doi.org/10.1002/recl.19931120215
https://doi.org/10.1002/recl.19931120215
Publikováno v:
Homeopathy. 98:83-87
Background Previous studies have investigated toxicity inhibition of optically active compounds by potentized preparations of their enantiomers. It was hypothesised that inhibition of toxicity may be stereospecific. This paper presents 2 studies inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3202f0932632a696aab66793c4ba57
https://doi.org/10.1016/j.homp.2009.02.002
https://doi.org/10.1016/j.homp.2009.02.002