Zobrazeno 1 - 10
of 92
pro vyhledávání: '"U Walker"'
Publikováno v:
Swiss Medical Weekly, Vol 140, Iss 2728 (2010)
Rituximab is an effective treatment of rheumatoid arthritis (RA), which has been approved for the treatment of moderate to severe disease in patients with an inadequate response to anti-TNF therapies. Rituximab differs from other available biological
Externí odkaz:
https://doaj.org/article/cd4e99dbec3f4655a38c317a677eaebb
Autor:
Willem Vanderlinden, Tine Brouns, Philipp U. Walker, Pauline J. Kolbeck, Lukas F. Milles, Wolfgang Ott, Philipp C. Nickels, Zeger Debyser, Jan Lipfert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Retroviral integration of DNA into the host genome is a point of no return in the replication cycle but how efficient integration can take place remains unclear. Here the authors demonstrate that consecutive nucleoprotein intermediates are increasing
Externí odkaz:
https://doaj.org/article/ba3ac588e06f42a0baa99862c45b98ff
Publikováno v:
Data in Brief, Vol 30, Iss , Pp 105404- (2020)
Nucleic acids are central to the storage and transmission of genetic information and play essential roles in many cellular processes. Quantitative understanding and modeling of their functions and properties requires quantitative experimental charact
Externí odkaz:
https://doaj.org/article/150a40c31f2c40b8b193f3f7c483b2e0
Autor:
S A Guler, A Sarbu, O Stadler, Y Allanore, V Bernardino, J H Distler, A Gabrielli, A Hoffmann-Vold, M Matucci-Cerinic, U Müller-Ladner, V Ortiz-Santamaria, S Rednic, V Riccieri, V Smith, S Ullman, U Walker, T Geiser, O Distler, B Maurer, F Kollert
Publikováno v:
12.02 - ILD/DPLD of known origin.
Autor:
A. C. Sarbu, S. Guler, O. Stadler, Y. Allanore, V. Bernardino, J. H. W. Distler, A. Gabrielli, A. M. Hoffmann-Vold, M. Matucci-Cerinic, U. Müller-Ladner, V. Ortiz-Santamaria, S. Rednic, V. Riccieri, V. Smith, S. Ullman, U. Walker, T. Geiser, O. Distler, B. Maurer, F. Kollert
Publikováno v:
Annals of the Rheumatic Diseases. 81:731-732
BackgroundSystemic sclerosis (SSc) is a heterogeneous autoimmune disease, with a high disease-related mortality and morbidity. A subset of patients show elevated CRP levels (20-35%), which has been reported as inflammatory SSc. Preliminary data sugge
Autor:
Achim Löf, Sophia Gruber, Martin Benoit, Jan Lipfert, Maria A. Brehm, Steffen M. Sedlak, Tobias Obser, Philipp U. Walker
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The physiological function of proteins is often critically regulated by mechanical forces acting on them. Single-molecule manipulation techniques such as atomic force microscopy or optical tweezers have enabled unprecedented insights int
Publikováno v:
Annals of the Rheumatic Diseases. 81:365-365
BackgroundAnti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) include granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) (1, 2). ANCA recognize the antimicrobial proteins proteinase 3 (PR3) or myeloperoxid
Publikováno v:
Annals of the Rheumatic Diseases. 81:1206.2-1207
BackgroundGiant cell arteritis (GCA) represents the most prevalent form of systemic vasculitis in elderly, and characterized by a remarkable heterogeneity regarding clinical and histological phenotype, pathogenetic mechanisms and treatment choice (1)
Autor:
A. Kocher, M. Simon, A. A. Dwyer, C. Blatter, J. Bogdanovic, P. Künzler-Heule, P. Villiger, D. Dan, O. Distler, U. Walker, D. Nicca
Publikováno v:
Annals of the Rheumatic Diseases. 81:138.2-139
BackgroundVariable disease presentation and symptom burden in patients living with systemic sclerosis (SSc) require a chronic care approach including competent, coordinated, multidisciplinary collaboration as well as self-management support targeting
Autor:
M. G. Lazzaroni, M. Wilson, E. Hensor, J. H. W. Distler, G. Cuomo, E. Siegert, U. Müller-Ladner, Y. Allanore, M. J. Salvador, B. Anic, U. Walker, L. Czirják, C. Ribi, C. M. Tanaseanu, A. Gabrielli, A. M. Hoffmann-Vold, O. Distler, F. Del Galdo
Publikováno v:
Annals of the Rheumatic Diseases. 81:743.2-744
BackgroundPatient Reported Outcomes (PROs) are central to measure how patients feel and function especially when determining the effect of disease modifying agents. In patients with Systemic Sclerosis associated Interstitial Lung Disease (SSc-ILD), d