Zobrazeno 1 - 10 of 13 pro vyhledávání: '"U S, Rajapaksa"'
1
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Autor: Christina Dold, Mariolina Salio, John Frater, Peter Simmonds, Christopher P. Conlon, J Slon-Campos, Z Yin, David I. Stuart, N F Schwabe, Guido C. Paesen, D Dong, Richard J. Cornall, Paul Thomson, T Lockett, Oliver W. Bayfield, U S Rajapaksa, J W Fry, P Supasa, Jonathan M. Grimes, R Levin, Wanwisa Dejnirattisai, Graham S. Ogg, Dannielle Wellington, Openshaw Pjm., Chen Y-L., Hawkins Dedp., P Zhang, Giorgio Napolitani, Tao Dong, J K Baillie, C Liu, Cesar Lopez-Camacho, Paul Sopp, M A Ansari, Alfred A. Antson, Ker D-S., Persephone Borrow, Susanna Dunachie, Andrew J. McMichael, Juthathip Mongkolsapaya, Yanchun Peng, B Wang, T Rostron, Shona C Moore, Lance Turtle, G Liu, T I de Silva, Krishanthi Subramaniam, Jeremy Ratcliff, Ho L-P., Benedikt M. Kessler, G Kerr, Yuguang Zhao, X Yao, Malcolm G Semple, Gavin R. Screaton, Paul Klenerman, Wayne Paes, R Jing, Alexander J. Mentzer, Y Zhang, Philip J. R. Goulder, Eleanor Barnes, Julian C. Knight
Publikováno v: Nature Immunology
NATURE IMMUNOLOGY
Nat Immunol
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines and therapeutics will depend on understanding viral immunity. We studied T cell memory in 42 patients following recovery from COVID-19 (28 with mild disease and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f78680cf7c854968fa13a2ef61dd0a2
https://ora.ox.ac.uk/objects/uuid:e5e926ec-b256-4608-9956-84db12d56741
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2
IFITM3‐specific antibody reveals IFN preferences and slow IFN induction of the antiviral factor IFITM3 in humans
Autor: Adi Abdel‐Haq, Liwei Zhang, Ian R. Humphreys, Jessica L. Forbester, Dannielle Wellington, Clare Verrill, Emma Bowes, Zixi Yin, Shokouh Makvandi-Nejad, David Maldonado-Perez, Henry Laurenson-Schafer, Tao Dong, Kerry A. Kite, U S Rajapaksa, Boquan Jin, Krishnageetha Manoharan
Publikováno v: European Journal of Immunology
Using a specific antibody, we found that expression of the viral restriction factor IFITM3 differs across cell types within the immune compartment with higher expression in myeloid rather than lymphoid cells. IFITM3 expression was increased following
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b824ee67640e38a86a4b03024f31ee94
https://orca.cardiff.ac.uk/id/eprint/138250/1/eji.202048706.pdf
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4
Broad and strong memory CD4 (+) and CD8 (+) T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients
Autor: Tao Dong, A Ansari, Persephone Borrow, Cesar Lopez-Camacho, Ker D-S., Openshaw Pjm., P Goulder, Juthathip Mongkolsapaya, Peter Simmonds, Gavin R. Screaton, Giorgio Napolitani, R Levin, D Dong, Eleanor Barnes, Peijun Zhang, Graham S. Ogg, Kenneth Baillie, P Supasa, Susanna Dunachie, G Paeson, Gu Liu, Georgina Kerr, Jeremy Ratcliff, J Slon-Campos, Wanwisa Dejnirattisai, Zixi Yin, T Lockett, Lance Turtle, Dannielle Wellington, X Yao, Richard J. Cornall, U S Rajapaksa, J W Fry, Julian C. Knight, Christopher P. Conlon, Jonathan M. Grimes, Christina Dold, Paul Sopp, Mariolina Salio, Andrew J. McMichael, F Antson, John Frater, Yanchun Peng, Malcolm G Semple, Paul Klenerman, Wayne Paes, T I de Silva, Benedikt M. Kessler, David I. Stuart, Oliver W. Bayfield, Krishanthi Subramaniam, Chang Liu, Shona C Moore, Yuguang Zhao, N F Schwabe, Alexander J. Mentzer, Chen Y-L., Paul Thomson, T Rostron, Hawkins Dedp.
Publikováno v: bioRxiv
COVID-19 is an ongoing global crisis in which the development of effective vaccines and therapeutics will depend critically on understanding the natural immunity to the virus, including the role of SARS-CoV-2-specific T cells. We have conducted a stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33bb7d89ab92980b64b630b8b389263
https://europepmc.org/articles/PMC7302222/
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5
HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation
Autor: Tao Dong, U S Rajapaksa, Andrew J. McMichael, Xiao-Ning Xu, Yanchun Peng, Demin Li
Human leukocyte antigen HLA-B alleles have better protective activity against HIV-1 than HLA-A alleles, possibly due to differences in HLA-restricted HIV-1-specific CD8+ cytotoxic T lymphocyte (CTL) function, but the mechanism is unknown. HIV-1 negat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df80c4c1a81dc10f73cbaff25c8ef92
https://ora.ox.ac.uk/objects/uuid:60700413-0d69-43fe-bad8-4f14e4429be7
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6
A comprehensive analysis of the impact of HIV on HCV immune responses and its association with liver disease progression in a unique plasma donor cohort
Autor: Emmanouela Repapi, Huanqin Sun, Tessa Lawrence, Yanchun Peng, Ning Liu, Yonghong Zhang, Sarah Rowland-Jones, Jane A. McKeating, Robert Thimme, Jinghua Liu, U S Rajapaksa, Hui-ping Yan, Ling Qin, Ke Hu, Tao Dong, Yan Zhao, Keyi Xu
Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0158037 (2016)
PLoS ONE
Objective Human Immunodeficiency Virus (HIV) and Hepatitis C virus (HCV) co-infection is recognized as a major cause of morbidity and mortality among HIV-1 infected patients. Our understanding of the impact of HIV infection on HCV specific immune res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587a9c4273977fd624d1d4920652100f
http://ora.ox.ac.uk/objects/uuid:abdbabc2-43d8-409a-8415-cce33c01913b
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7
Molecular diversity of Mycobacterium tuberculosis isolates from patients with pulmonary tuberculosis in Sri Lanka
Autor: Tommie C. Victor, U S Rajapaksa, S.M.P. Senevirathne, Robin M. Warren, A. J. Perera
Publikováno v: Transactions of the Royal Society of Tropical Medicine and Hygiene. 102:997-1002
The strain diversity of 100 Mycobacterium tuberculosis isolates collected over a period of 18 months from tuberculosis (TB) cases in Sri Lanka was studied by spoligotyping. When compared to the international spoligotyping database, 43 spoligotype pat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d3a1ec22f353ff813c1f0e1f275c37
https://doi.org/10.1016/j.trstmh.2008.04.025
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8
Microculture for the isolation ofLeishmaniaparasites from cutaneous lesions — Sri Lankan experience
Autor: U S Rajapaksa, Nadira D. Karunaweera, R. L. Ihalamulla
Publikováno v: Annals of Tropical Medicine & Parasitology. 99:571-575
Novy, McNeal and Nicolle (NNN) medium and Evans' modified Tobie's medium are two conventional media for the isolation of Leishmania parasites in in-vitro cultures. Both are biphasic, with a solid layer of blood agar, and are normally prepared in glas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b670a053720e8eb29cea32931b27b0f5
https://doi.org/10.1179/136485905x51364
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9
Sublineages of Beijing Strain of Mycobacterium tuberculosis in Sri Lanka
Autor: U S Rajapaksa, A. J. Perera
Publikováno v: Indian Journal of Microbiology. 51:410-412
Strains of the Beijing/W genotype of Mycobacterium tuberculosis have been responsible for large outbreaks of tuberculosis around the world, sometimes involving multi-drug resistance. It has been shown that more recently evolved Beijing sublineages ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f2313a3581ffed6c29f541748e670f
https://doi.org/10.1007/s12088-011-0150-1
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