Zobrazeno 1 - 10
of 34
pro vyhledávání: '"U P, Thorgeirsson"'
Autor:
D E, Gomez, U P, Thorgeirsson
Publikováno v:
Methods in molecular medicine. 9
Successful procedures for the isolation and culture of large-vessel endothelial cells (EC), were first reported in the early seventies (1,2). Since then, microvascular EC have been isolated from various organs, such as adrenal gland (3), brain (4), s
Autor:
H, Yoshiji, S, Kuriyama, Y, Miyamoto, U P, Thorgeirsson, D E, Gomez, M, Kawata, J, Yoshii, Y, Ikenaka, R, Noguchi, H, Tsujinoue, T, Nakatani, S S, Thorgeirsson, H, Fukui
Publikováno v:
Hepatology (Baltimore, Md.). 32(6)
Tissue inhibitor of metalloproteinases-1 (TIMP-1) has been shown to be increased in liver fibrosis development both in murine experimental models and human samples. However, the direct role of TIMP-1 during liver fibrosis development has not been def
Publikováno v:
Anticancer research. 20(4)
The synthetic flavonoid flavone acetic acid (FAA) has anti-tumor activity against a variety of transplanted tumors in mice through mechanisms which likely involve effects on tumor vasculature and the host immune system. The aims of the present in vit
Autor:
D J, Schoeffner, U P, Thorgeirsson
Publikováno v:
In vivo (Athens, Greece). 14(1)
Nonhuman primates are a valuable experimental model for the evaluation of human carcinogenic risk but have not been widely used for various reasons, such as high cost and lack of availability. The present review discusses the findings from a long-ter
Publikováno v:
In vivo (Athens, Greece). 14(1)
With the ever-increasing evidence that the extracellular matrix (ECM) can stimulate tumor growth, it follows that inhibiting the synthesis of tumor-derived stroma may be a potential therapeutic target of cancer progression. The proline analog cis-hyd
Autor:
S R, Harris, U P, Thorgeirsson
Publikováno v:
In vivo (Athens, Greece). 12(6)
Angiogenesis is now recognized as a critical process in tumor progression and is required for solid tumors to grow beyond a few millimeters in size. The transition from a non angiogenic to an angiogenic phenotype and subsequent tumor vascularization
Publikováno v:
Nutrition and cancer. 31(3)
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a carcinogenic heterocyclic amine derived from cooked meat. Mammary gland tumors were induced in female Sprague-Dawley rats given 10 doses of PhIP (75 mg/kg po) once per day from 43 days of ag
Autor:
H, Yoshiji, S R, Harris, E, Raso, D E, Gomez, C K, Lindsay, M, Shibuya, C C, Sinha, U P, Thorgeirsson
Publikováno v:
International journal of cancer. 75(1)
The tissue inhibitor of metalloproteinases-1 (TIMP-1) has at least 2 independent functions, i.e., regulation of matrix metalloproteinases and erythroid-potentiating activity. We investigated the effects of TIMP-1 over-expression on tumor growth, usin
Publikováno v:
Invasionmetastasis. 17(5)
Cloned v-raf, v-raf/v-myc, and spontaneously transformed rat liver epithelial (RLE) cell lines were examined for meastatic capability in nude mice, using the LacZ gene as a marker for quantitation of micrometastases. Six cloned lines (R3611-T lines)
Publikováno v:
International journal of cancer. 69(2)
Tissue inhibitor of metalloproteinases-1 (TIMP-1) is known to have at least 2 distinct types of activity, i.e., as a regulator of collagenolytic activity, and erythroid potentiating activity (EPA). In this study, we examined the expression of TIMP-1