Zobrazeno 1 - 10
of 126
pro vyhledávání: '"U K Hanisch"'
Autor:
S. Ribes, L. Zacke, S. Nessler, N. Saiepour, E. Avendaño-Guzmán, M. Ballüer, U. K. Hanisch, R. Nau
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Abstract Background Bacterial meningitis is a fatal disease with a mortality up to 30% and neurological sequelae in one fourth of survivors. Available vaccines do not fully protect against this lethal disease. Here, we report the protective effect of
Externí odkaz:
https://doaj.org/article/48bd525594714007bb2206482d10b752
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences. 94:14054-14059
Insulin-like growth factors-I and -II (IGF-I and -II) are structurally related mitogenic polypeptides with potent growth promoting effects. These peptides and their corresponding IGF-I and -II receptors are selectively localized in the brain. To date
Publikováno v:
Endocrinology. 135:2465-2472
The cytokine interleukin-2 (IL-2) exerts numerous effects within the immune as well as the central nervous system and is thought to serve as a humoral signal in their communication. Brain-derived or blood-borne IL-2 may also control the activity of t
Publikováno v:
European journal of immunology. 31(7)
Central nervous system (CNS) infections caused by Streptococcus pneumoniae still have a disastrous outcome. Underlying immunological and CNS cellular events are largely enigmatic. We used pneumococcal cells walls (PCW) to investigate microglial respo
Autor:
R, Stohwasser, J, Giesebrecht, R, Kraft, E C, Müller, K G, Häusler, H, Kettenmann, U K, Hanisch, P M, Kloetzel
Publikováno v:
Glia. 29(4)
The 20S proteasome is a multicatalytic threonine protease and serves to process peptides that are subsequently presented as antigenic epitopes by MHC class I molecules. In the brain, microglial cells are the major antigen presenting cells and they re
Publikováno v:
Neuroscience and biobehavioral reviews. 21(5)
Calcitonin generelated peptide (CGRP) is a neuropeptide discovered by a molecular approach over 10 years ago. More recently, islet amyloid polypeptide or amylin, and adrenomedullin were isolated from human insulinoma and pheochromocytoma respectively
Publikováno v:
Gene therapy. 3(6)
Using a minipump combined with stereotaxic techniques allows continuous delivery of therapeutic genetic materials into the brain. We investigated the therapeutic efficacy of liposome-mediated HSVtk gene transfer of experimental brain F98 glioma follo