Zobrazeno 1 - 10
of 28
pro vyhledávání: '"U H Weidle"'
Publikováno v:
Clinical and Experimental Metastasis. 17:641-648
Interactions of tumor cells with the endothelium and tissue stroma are considered to be critical steps in metastasis formation and progression of cancer. To identify cellular receptors that mediate the binding of tumor cells to endothelium, a murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22147e70944d10dee2e91c7177b09ab8
https://doi.org/10.1023/a:1006790912877
https://doi.org/10.1023/a:1006790912877
Autor:
U H Weidle, Otto Majdic, Johannes Stöckl, Hannes Stockinger, I Bartke, Walter Knapp, J Bohuslav, Vaclav Horejsi, C Hansmann
Publikováno v:
The Journal of Experimental Medicine
The glycosylphosphatidylinositol (GPI)-anchored membrane protein urokinase plasminogen activator-receptor (uPA-R; CD87) is one of the key molecules involved in migration of leukocytes and tumor cells. uPA bound to uPA-R provides the cell proteolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e9bb69a6db377e0c260b9e0f46bfd4
https://doi.org/10.1084/jem.181.4.1381
https://doi.org/10.1084/jem.181.4.1381
Publikováno v:
Molecular Immunology. 32:9-20
In order to investigate the feasibility of shuffling effector functions of monoclonal antibodies, we constructed chimeric antibodies with fused heavy chains. The derivatives studied are based on a monoclonal antibody directed against the alpha chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6c81a351e50e5426e7f768a52144a6
https://doi.org/10.1016/0161-5890(94)00138-q
https://doi.org/10.1016/0161-5890(94)00138-q
Autor:
Andrew J. Racher, U. H. Weidle, José L. Moreira, Michael Wirth, Hansjörg Hauser, J. B. Griffiths, Paula M. Alves, Manuel J.T. Carrondo
Publikováno v:
Applied Microbiology and Biotechnology. 40:851-856
The growth and productivity of an Sp2/0 cell line, F3b10, expressing a recombinant antibody (rAb) and BHK21 cells expressing either the same rAb from the same plasmids (BHK.IgG) or secreted alkaline phosphatase (SEAP) (BHK.SEAP) were investigated. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e74d81565e52cf9c426fd36498da992
https://doi.org/10.1007/bf00173987
https://doi.org/10.1007/bf00173987
Publikováno v:
The Journal of Immunology. 150:4610-4619
A bispecific antibody recognizing both the alpha- and beta-chains of the IL-2R was generated by sulfhydryl-directed chemical reassociation of monovalent Fab' fragments prepared from the anti-alpha mAb 33B3.1 (rat IgG2a) and from the anti-beta mAb A41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d9e51297ab3f6f00aaac4d2f96f6e0
https://doi.org/10.4049/jimmunol.150.10.4610
https://doi.org/10.4049/jimmunol.150.10.4610
Publikováno v:
Anticancer research. 21(6A)
In order to identify genes associated with metastasis of mammary carcinoma, we compared the transcriptional profile (Affymetrix chip technology) of two cell lines derived from primary mammary carcinoma, three cell lines derived from bone marrow micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ee7ad2815999f45c4ed515de9c0b946
https://pubmed.ncbi.nlm.nih.gov/11911250
https://pubmed.ncbi.nlm.nih.gov/11911250
Publikováno v:
Anticancer research. 21(5)
In order to identify genes associated with metastasis of ductal pancreatic adenocarcinoma we investigated pancreatic tumor cell lines derived from an orthotopic pancreatic tumor model in SCID mice. Transcriptional profiling (Affymetrix Gene Chip Tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d460147c5f3585555cc4951cfd48533a
https://pubmed.ncbi.nlm.nih.gov/11848476
https://pubmed.ncbi.nlm.nih.gov/11848476
Publikováno v:
Anticancer research. 21(3B)
In order to identify genes associated with the metastatic phenotype we have compared the expression pattern of 6800 genes in a metastatic (NMCL-1) versus a non-metastatic (530) human melanoma cell line making use of DNA microarrays. The differentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b269dd324b73419e5e61f01e1cc787bc
https://pubmed.ncbi.nlm.nih.gov/11497253
https://pubmed.ncbi.nlm.nih.gov/11497253
Publikováno v:
Anticancer research. 21(3B)
Cell lines 4A4 and 2C5 are the respective metastatic and non-metastatic variants of the human mammary carcinoma cell line MDA-MB-435 in the nude mouse system. We compared the transcriptional profile of approximately 5000 full-length genies using the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82019ca5ffe7b9135c3454fac4d3983b
https://pubmed.ncbi.nlm.nih.gov/11497258
https://pubmed.ncbi.nlm.nih.gov/11497258
Publikováno v:
Anticancer research. 21(2A)
We have recently described a new member of the PMP22/gas3 family of plasma membrane proteins referred to as THW. This gene is located on chromosome 6q and preliminary data have indicated a possible tumor suppressor gene function. We have therefore in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff0ae03f89d46e6977c0eafc4429efd8
https://pubmed.ncbi.nlm.nih.gov/11396142
https://pubmed.ncbi.nlm.nih.gov/11396142