Zobrazeno 1 - 10
of 43
pro vyhledávání: '"U H, Ehling"'
Publikováno v:
Genetical Research. 72:177-183
Ifosfamide induced dominant lethal mutations in spermatozoa of mice at doses of 200 and 300 mg/kg and in spermatids and spermatocytes at 600 mg/kg. The highest dose also induced specific-locus mutations in post-spermatogonial germ-cell stages of mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c540b61b1fd961444658ffc00d5c126c
https://doi.org/10.1017/s0016672398003413
https://doi.org/10.1017/s0016672398003413
Publikováno v:
Teratogenesis, carcinogenesis, and mutagenesis. 19(5)
An autoradiographic procedure was used to measure unscheduled DNA synthesis (UDS, DNA repair synthesis) in spermatogonial and postspermatogonial cell stages of mice after treatment with two doses of N-ethyl-N-nitrosourea (ENU) and N-methyl-N-nitrosou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6212bfc015be9133be20dc29f9812be1
https://pubmed.ncbi.nlm.nih.gov/10495451
https://pubmed.ncbi.nlm.nih.gov/10495451
Autor:
Diana Anderson, Antonella Russo, Ilse-Dore Adler, U.-H. Ehling, J. Laehdetie, Francesca Pacchierotti, R. Benigni, Ad D. Tates
The project ‘Detection of Germ Cell Mutagens’ was designed with three major goals: (1) Detection and characterization of germ-cell mutagens; (2) standardization and validation of new germ-cell tests; and (3) development of a data base on germ-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513666b3c01315ad7ea68e8e132e5634
http://hdl.handle.net/11577/125591
http://hdl.handle.net/11577/125591
Autor:
U H, Ehling
Publikováno v:
Progress in clinical and biological research. 372
The occurrence of induced dominant genetic damage can be measured by comparing mutation frequencies in first generation descendants from treated and untreated populations, but for many characters, it is difficult to distinguish between the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bf014d5002bb50cee84fe7984e86ad1
https://pubmed.ncbi.nlm.nih.gov/1956941
https://pubmed.ncbi.nlm.nih.gov/1956941
Autor:
U H, Ehling
Publikováno v:
Progress in clinical and biological research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de7eae27c5f4c2720c4d72f9b816a931
https://pubmed.ncbi.nlm.nih.gov/2199980
https://pubmed.ncbi.nlm.nih.gov/2199980
Autor:
H. Frohberg, R. Roll, D. Müller, W. Buselmaier, L. Machemer, M. Schulze-Schencking, J. Kratochvilova, R. Lang, G. Röhrborn, U. H. Ehling, J. Dýcka, D. Lorke, H. Wiemann, J. Peh
Publikováno v:
Archives of Toxicology. 39:173-185
The members of the work group “Dominant Lethal Mutations of the ad hoc Committee Chemogenetics” jointly carried out experimental studies in the period from November 1972 until February 1976. On the basis of the results obtained and the experience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd437d3868cc327700e3e1b86a552ba2
https://doi.org/10.1007/bf00368226
https://doi.org/10.1007/bf00368226
Autor:
U. H. Ehling
Publikováno v:
Archives of Toxicology. 46:123-138
Methods available to study the induction of gene mutations in mammalian germ cells are described. Results of specific locus experiments with mice indicate the importance of this test for the validation of short term tests. Out of 5 compounds studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b56c8374525bc5a7de85e5d106b0e02
https://doi.org/10.1007/bf00361251
https://doi.org/10.1007/bf00361251
Autor:
U. H. Ehling
Publikováno v:
Risk Analysis. 8:45-57
Screening methods are used for hazard identification. Assays for heritable mutations in mammals are used for the confirmation of short-term test results and for the quantification of the genetic risk. There are two main approaches in making genetic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e460b115a22445762411148798a75db
https://doi.org/10.1111/j.1539-6924.1988.tb01153.x
https://doi.org/10.1111/j.1539-6924.1988.tb01153.x
Autor:
U. H. Ehling, M. L. Randolph
Publikováno v:
Genetics. 47:1543-1555
Results are reported from an experiment designed to test the feasibility of measuring part of the overall genetic damage of irradiation by means of skeletal studies in the F/sub 1/ generation. Male 101-strain mice were irradiated, using different rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e52b7c3b28bcc0a172c07fd0fec9c6e
https://doi.org/10.1093/genetics/47.11.1543
https://doi.org/10.1093/genetics/47.11.1543
Autor:
U. H. Ehling
Publikováno v:
Genome. 31:841-843
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5bc37163492a5fa88d100df84266b27
https://doi.org/10.1139/g89-148
https://doi.org/10.1139/g89-148