Zobrazeno 1 - 10
of 11
pro vyhledávání: '"U G, Eriksson"'
Autor:
O Holz, M W Sadiq, J Nehrig, B Ellinghusen, N Struß, U G Eriksson, M Fridén, S Stomilovic, A Lundqvist, J Hohlfeld
Publikováno v:
05.01 - Airway pharmacology and treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca19dda9fde9098c94d80ad37ebfa98
https://doi.org/10.1183/13993003.congress-2022.2960
https://doi.org/10.1183/13993003.congress-2022.2960
Publikováno v:
Pharmaceutical research. 1(5)
Paramagnetic nitroxyl-containing compounds have been useful as contrast agents in magnetic resonance imaging (MRI) experiments in animals. Preliminary information on the metabolic fate, pharmacokinetic behavior, stability in tissues, and chemical red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::683004cd19db606fec337b2065ea40fa
https://pubmed.ncbi.nlm.nih.gov/24277329
https://pubmed.ncbi.nlm.nih.gov/24277329
Publikováno v:
Pharmaceutical research. 2(2)
Two nitroxide spin labels called PCA and TES have been used experimentally as contrast enhancing agents in magnetic resonance imaging. Pharmacokinetic data for these nitroxides, after intravenous administration to three dogs at two dose levels (0.1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17839a3c9594a00d80406cdb6145e5de
https://pubmed.ncbi.nlm.nih.gov/24272611
https://pubmed.ncbi.nlm.nih.gov/24272611
Autor:
E Jensen, Susanne Johansson, M Cullberg, Karin Wåhlander, K Dunér, U G Eriksson, Maria Wollbratt, M Elg
Publikováno v:
International journal of clinical pharmacology and therapeutics. 49(4)
Objective The novel oral anticoagulant AZD0837 is currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial fibrillation. AZD0837 is bioconverted to AR-H067637, a selective and reversible direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e3de4d82ba3b16dcd4c842bbcc65fc
https://pubmed.ncbi.nlm.nih.gov/21429440
https://pubmed.ncbi.nlm.nih.gov/21429440
Publikováno v:
British journal of clinical pharmacology. 51(1)
The purpose of this study was to characterize the relationship between the degree of anticoagulation, assessed by APTT, and the plasma concentration of inogatran in healthy subjects and in patients with coronary artery disease.Data from five phase I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::698d3a48aeae197cff4833c9bb141e9a
https://pubmed.ncbi.nlm.nih.gov/11167667
https://pubmed.ncbi.nlm.nih.gov/11167667
Publikováno v:
Biopharmaceuticsdrug disposition. 19(1)
Pharmacokinetics, excretion, and metabolism of inogatran, a low-molecular-weight thrombin inhibitor, were studied in the rat, dog, and cynomolgus monkey. After intravenous administration the half-life was short in all three animal species, due to a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd5402d09a38d8ce497351dd1ca7074e
https://pubmed.ncbi.nlm.nih.gov/9510985
https://pubmed.ncbi.nlm.nih.gov/9510985
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 261(3)
The effects of naringenin, quercetin and kaempferol, flavonoids found in grapefruit as glycosides, on the metabolism of nifedipine and the enantiomers of felodipine were studied in microsomes from rat and human liver. Flavonoid concentrations of 10,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca89cfffea8278fa9b3521245e94ebea
https://pubmed.ncbi.nlm.nih.gov/1602384
https://pubmed.ncbi.nlm.nih.gov/1602384
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 19(5)
Felodipine, a 1,4-dihydropyridine derivative, is a potent, vasoselective calcium antagonist that is used clinically as a racemic mixture of two stereoisomers. In the rat, dog, and human, the bioavailability of an oral dose is about 15% because of hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2c744a77ec327352ebceada9da63dc1
https://pubmed.ncbi.nlm.nih.gov/1686232
https://pubmed.ncbi.nlm.nih.gov/1686232
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 21(1)
1. A pseudoracemic mixture of deuterated (S)-felodipine and unlabelled (R)-felodipine was administered as single i.v. or oral doses to four dogs. Plasma concentrations of the enantiomers and their corresponding pyridine metabolites were determined by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747cb259b6f1ad03649e9dda2b8f28b4
https://pubmed.ncbi.nlm.nih.gov/2003369
https://pubmed.ncbi.nlm.nih.gov/2003369
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 15(2)
Paramagnetic nitroxyl spin labels have potential clinical utility as contrast agents in proton magnetic resonance imaging. Reduction of the nitroxyl moiety in vivo results in the formation of the diamagnetic hydroxylamine, which lacks contrast-enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6302c7d9f258a5574f20ffd8ed6eada
https://pubmed.ncbi.nlm.nih.gov/2882971
https://pubmed.ncbi.nlm.nih.gov/2882971