Clinical and transcriptomic features of persistent exacerbation‐prone severe asthma in U‐BIOPRED cohort

Autor: Uruj Hoda, Stelios Pavlidis, Aruna T. Bansal, Kentaro Takahashi, Sile Hu, Francois Ng Kee Kwong, Christos Rossios, Kai Sun, Pankaj Bhavsar, Matthew Loza, Frederic Baribaud, Pascal Chanez, Stephen J. Fowler, Ildiko Horvath, Paolo Montuschi, Florian Singer, Jacek Musial, Barbro Dahlen, Norbert Krug, Thomas Sandstrom, Dominic E. Shaw, Rene Lutter, Louise J. Fleming, Peter H. Howarth, Massimo Caruso, Ana R. Sousa, Julie Corfield, Charles Auffray, Bertrand De Meulder, Diane Lefaudeux, Sven‐Erik Dahlen, Ratko Djukanovic, Peter J. Sterk, Yike Guo, Ian M. Adcock, Kian Fan Chung, the U‐BIOPRED study group

Publikováno v: Clinical and Translational Medicine, Vol 12, Iss 4, Pp n/a-n/a (2022)

Abstract Background Exacerbation‐prone asthma is a feature of severe disease. However, the basis for its persistency remains unclear. Objectives To determine the clinical and transcriptomic features of frequent exacerbators (FEs) and persistent FEs

Externí odkaz: https://doaj.org/article/472cffbdc9ba4c16ac2d4d6cd89330da

Characteristics of Type-2 High and Low Asthma in the U-biopred Cohort

Autor: K. Yevdokimova, K. Hao, L. Rogers, null on behalf of the U-BIOPRED Study Group

Publikováno v: B69. AIRWAY INJURY AND REPAIR: MECHANISMS AND TREATMENT.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::206d07f978b875051c123c15b63ce6d4
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4032

The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts

Autor: Hou, R, Ye, G, Cheng, X, Shaw, DE, Bakke, PS, Caruso, M, Dahlen, B, Dahlen, S-E, Fowler, SJ, Horváth, I, Howarth, P, Krug, N, Montuschi, P, Sanak, M, Sandström, T, Auffray, C, De Meulder, B, Sousa, AR, Adcock, IM, Fan Chung, K, Sterk, PJ, Skipp, PJ, Schofield, J, Djukanović, R, U-BIOPRED Study Group

Publikováno v: U-BIOPRED Study Group 2023, ' The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts ', Brain, Behavior, and Immunity, vol. 111, pp. 249-258 . https://doi.org/10.1016/j.bbi.2023.04.011

BACKGROUND: Growing evidence indicates high comorbid anxiety and depression in patients with asthma. However, the mechanisms underlying this comorbid condition remain unclear. The aim of this study was to investigate the role of inflammation in comor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f54e16b71445fe5838b71e25373385
https://publica.fraunhofer.de/handle/publica/442951

Radiomics for severe asthma phenotyping and endotyping

Autor: N Zounemat Kermani, G Macis, P S Bakke, M Caruso, P Chanez, R Djukanovic, S J Fowler, Y Guo, I Horvath, P H Howarth, A I Maitland-Van Der Zee, M Malerba, G Roberts, M Sanak, D Shaw, S J Wilson, S Siddiqui, S Dahlen, K F Chung, I M Adcock, P Montuschi, On Behalf Of The U-Biopred Study Group

Publikováno v: ERS International Congress 2022

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209abdf58a3dc30e4941413561c41d35
http://hdl.handle.net/10044/1/104553

Multi-ancestry genome-wide association study of asthma exacerbations

Autor: Herrera Luis, Esther, Ortega, Victor E., Ampleford, Elizabeth J., Sio, Yang Yie, Granell, Raquel, de Roos, Emmely, Terzikhan, Natalie, Elorduy Vergara, Ernesto, Hernández Pacheco, Natalia, Pérez García, Javier, Martín González, Elena, Lorenzo Díaz, Fabián, Hashimoto, Simone, Brinkman, Paul, U-BIOPRED Study Group, Jorgensen, Andrea L., Yan, Qi, Forno, Erick, Vijverberg, Susanne J., Lethem, Ryan, Espuela Ortiz, Antonio, Gorenjak, Mario, Eng, Celeste, González Pérez, Ruperto, Hernández Pérez, José M., Poza Guedes, Paloma, Sardón Prado, Olaia, Corcuera Elosegui, Paula, Hawkins, Greg A., Marsico, Annalisa, Bahmer, Thomas, Rabe, Klaus F., Hansen, Gesine, Kopp, Matthias Volkmar, Rios, Raimon, Cruz Carmona, María Jesús, González Barcala, Francisco Javier, Olaguibel, José María, Plaza, Vicente, Quirce, Santiago, Canino, Glorisa, Cloutier, Michelle, Del Pozo, Victoria, Rodríguez Santana, José R., Korta Murua, José Javier, Villar, Jesús, Potočnik, Uroš, Figueiredo, Camila, Kabesch, Michael, Mukhopadhyay, Somnath, Pirmohamed, Munir, Hawcutt, Daniel B., Melén, Erik, Palmer, Colin N., Turner, Steven, Maitland-van der Zee, Anke H., von Mutius, Erika, Celedón, Juan C., Brusselle, Guy, Chew, Fook Tim, Bleecker, Eugene, Meyers, Deborah, Burchard, Esteban G., Pino Yanes, María

Publikováno v: Herrera-Luis, E, Ortega, V, Ampleford, E, Sio, Y Y, Granell, R, Lethem, R, Pino-Yanes, M & et, A 2022, ' Multi-ancestry genome-wide association study of asthma exacerbations ', Pediatric Allergy and Immunology, vol. 33, no. 6, e13802 . https://doi.org/10.1111/pai.13802
Addi. Archivo Digital para la Docencia y la Investigación
instname
Pediatric Allergy and Immunology, 33(6):e13802. Blackwell Publishing
Pediatr. Allergy Immunol. 33:e13802 (2022)
PEDIATRIC ALLERGY AND IMMUNOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Scientia
Herrera-Luis, Esther; Ortega, Victor E; Ampleford, Elizabeth J; Sio, Yang Yie; Granell, Raquel; de Roos, Emmely; Terzikhan, Natalie; Vergara, Ernesto Elorduy; Hernandez-Pacheco, Natalia; Perez-Garcia, Javier; Martin-Gonzalez, Elena; Lorenzo-Diaz, Fabian; Hashimoto, Simone; Brinkman, Paul; Jorgensen, Andrea L; Yan, Qi; Forno, Erick; Vijverberg, Susanne J; Lethem, Ryan; Espuela-Ortiz, Antonio; ... (2022). Multi-ancestry genome-wide association study of asthma exacerbations. Pediatric allergy and immunology, 33(6), e13802. Wiley-Blackwell 10.1111/pai.13802
Pediatr Allergy Immunol
Pediatric allergy and immunology, 33(6):e13802. Blackwell Munksgaard

Background: Asthma exacerbations are a serious public health concern due to high healthcare resource utilization, work/school productivity loss, impact on quality of life, and risk of mortality. The genetic basis of asthma exacerbations has been stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a36b2940a1b9606b47e851a2c57a5c
https://hdl.handle.net/1983/3527f915-59cc-4a55-aae9-17f281e40243