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Akademický článek

Studies on the link between HMG-CoA reductase and cholesterol 7 alpha-hydroxylase in lymph-fistula rats: evidence for both transcriptional and post-transcriptional mechanisms for down-regulation of the two enzymes by bile acids

Autor: I Björkhem, U Andersson, E Sudjama-Sugiaman, G Eggertsen, P Hylemon

Publikováno v: Journal of Lipid Research, Vol 34, Iss 9, Pp 1497-1503 (1993)

The mechanism of down-regulation of hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase by cholic acid (CA) and chenodeoxycholic acid (CDCA) was investigated in rats with a lymph fistula. In accordance with the contention that bile acids ar

Externí odkaz: https://doaj.org/article/e753c16f3c734e06982c781272f14547

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Akademický článek

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Sexual harassment among employees and students at a large Swedish university: who are exposed, to what, by whom and where – a cross-sectional prevalence study

Autor: A. Agardh, G. Priebe, M. Emmelin, J. Palmieri, U. Andersson, P-O Östergren

Publikováno v: BMC Public Health. 22

Background Sexual harassment (SH) in the workplace is prevalent and associated with poor health. Universities are large workplaces with complex formal and informal power relations, which may influence the prevalence of SH. Although employees and stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233872a1de61cb1b94ef28ce55cc7875
https://doi.org/10.1186/s12889-022-14502-0

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Akademický článek

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Akademický článek

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Akademický článek

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Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell

Publikováno v: Journal of the American Chemical Society. 143:3416-3429

The extra hepatic delivery of antisense oligonucleotides (ASOs) remains a challenge and hampers the widespread application of this powerful class of therapeutic agents. In that regard, pancreatic beta cells are a particularly attractive but challengi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b854feb4ca478194b8ccb06db2a2c928
https://doi.org/10.1021/jacs.0c12043

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Outcomes of the European Federation of Pharmaceutical Industries and Associations Oligonucleotide Working Group Survey on Nonclinical Practices and Regulatory Expectations for Therapeutic Oligonucleotide Safety Assessment

Autor: Lauren Mihalcik, Patrik U. Andersson, Yann Tessier, Chidozie Amuzie, William E. Achanzar, Jonathan G. Moggs, Laurence O. Whiteley, Joel D. Parry

Publikováno v: Nucleic Acid Therapeutics. 31:7-20

The Oligonucleotide Working Group of the European Federation of Pharmaceutical Industries and Associations (EFPIA) conducted a survey of companies to understand the trends in nonclinical practices and regulatory expectations for oligonucleotide drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962ae22e6ce4d8eebd81264de4313d70
https://doi.org/10.1089/nat.2020.0892

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A cross-industry assessment of the flow rate-time profiles of test equipment typically used for dry-powder inhaler (DPI) testing: Part 1 – compendial apparatuses

Autor: Mark Hammond, Roland Greguletz, Daryl L. Roberts, Patrik U. Andersson, F Chambers, M. Hamilton, H Mohammed, A Cooper, Christopher M. Shelton, Jolyon P. Mitchell, G Daniels, Mark Copley, Hendrik K. Versteeg

Publikováno v: Aerosol Science and Technology. 54:1424-1447

We report a cross-industry study characterizing flow rate-time profiles of equipment used for testing dry-powder inhalers (DPIs). Nine organizations used the same thermal mass flow sensor to record...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ce1b3446d4887ee31322276d57c176e
https://doi.org/10.1080/02786826.2020.1792824

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Akademický článek

Reactions of H+(pyridine)m(H2O)n and H+(NH3)1(pyridine)m(H2O)n with NH3: experiments and kinetic modelling

Autor: E. Uggerud, P. U. Andersson, A. S. Zatula, M. J. Ryding, Å. M. Jonsson

Publikováno v: Atmospheric Chemistry and Physics, Vol 12, Iss 6, Pp 2809-2822 (2012)

Reactions between pyridine containing water cluster ions, H+(pyridine)1(H2O)n, H+(pyridine)2(H2O)n and H+(NH3)1(pyridine)1(H2O)n (n up to 15) with NH3 have been studied experimentally using a quadrupole time-of-flight mass spectrometer. The product i

Externí odkaz: https://doaj.org/article/2ee6a6a13d454e788b4e3c36644f0386

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