Zobrazeno 1 - 10
of 42
pro vyhledávání: '"U A, Liberman"'
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 73:105-112
It was previously shown that 1,25-dihydroxyvitamin D(3) (1, 25(OH)(2)D(3)) enhances the cytotoxic activity of tumor necrosis factor alpha (TNFalpha), doxorubicin and menadione. A feature shared by these anticancer agents is the involvement of reactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ca08a38fdc619195a8f84cff3a8492
https://doi.org/10.1016/s0960-0760(00)00068-6
https://doi.org/10.1016/s0960-0760(00)00068-6
Publikováno v:
Journal of Endocrinology. 149:327-333
Renal cell carcinoma is a chemotherapy-resistant tumor which is relatively responsive to immunotherapy. Immunotherapeutic regimes employ interferons or interleukin 2 with or without lymphokine-activated killer cells. Secondary cytokines, induced by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7b601850720880cb5d5219715aff96
https://doi.org/10.1677/joe.0.1490327
https://doi.org/10.1677/joe.0.1490327
Publikováno v:
The Journal of endocrinology. 173(3)
In addition to its known effects on keratinocyte proliferation and differentiation, the hormonal form of vitamin D, 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), has been shown to protect keratinocytes from UV- and chemotherapy-induced damage. Epider
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74436df735ba384bb1021b106d4f2782
https://pubmed.ncbi.nlm.nih.gov/12065242
https://pubmed.ncbi.nlm.nih.gov/12065242
Autor:
U A Liberman
Publisher Summary This chapter focuses on the hereditary deficiencies in vitamin D action, which occur due to disturbances in the synthesis of the hormonal form of the vitamin, 1,25-dihydroxyvitamin Dl,(25(OH)2D-calcitriol), or defects in the interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612efeb2c3a437674eac5d3296dd1308
https://doi.org/10.1016/b978-012098652-1/50169-4
https://doi.org/10.1016/b978-012098652-1/50169-4
Publikováno v:
Cancer research. 61(4)
The anticancer activity of the hormonal form of vitamin D, 1,25-dihydroxyvitamin D [1,25(OH)2D], is associated with inhibition of cell cycle progression, induction of differentiation, and apoptosis. In addition, 1,25(OH)2D3 augments the activity of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c95f85d93f31ce879d371a4f053464ab
https://pubmed.ncbi.nlm.nih.gov/11245448
https://pubmed.ncbi.nlm.nih.gov/11245448
Autor:
A, Ravid, D, Rocker, A, Machlenkin, C, Rotem, A, Hochman, G, Kessler-Icekson, U A, Liberman, R, Koren
Publikováno v:
Cancer research. 59(4)
1,25-Dihydroxyvitamin D3 (1,25(OH)2D3), the hormonal form of vitamin D, has anticancer activity in vivo and in vitro. Doxorubicin exerts its cytotoxic effect on tumor cells mainly by two mechanisms: (a) generation of reactive oxygen species (ROS); an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24f7734cf78c5ad214aca31fb7f52761
https://pubmed.ncbi.nlm.nih.gov/10029076
https://pubmed.ncbi.nlm.nih.gov/10029076
Publikováno v:
The British journal of dermatology. 139(6)
Calpain is a ubiquitous neutral calcium-activated thiol protease that is implicated in various cellular functions including exocytosis, cell fusion, apoptosis and proliferation. The calpain system is composed of the enzymes mu-calpain and m-calpain a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0058e0f7a0e5b0f994d341158e32b901
https://pubmed.ncbi.nlm.nih.gov/9990355
https://pubmed.ncbi.nlm.nih.gov/9990355
Publikováno v:
Endocrinology. 140(2)
Topical treatment of normal skin with 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] or its synthetic analogs results in enhanced keratinocyte proliferation. Autocrine growth factors belonging to the epidermal growth factor (EGF) family play a major role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b98379ff6c5929db83fe751eee2b607d
https://pubmed.ncbi.nlm.nih.gov/9927298
https://pubmed.ncbi.nlm.nih.gov/9927298
Publikováno v:
Molecular and cellular endocrinology. 142(1-2)
The mast cell lines rat basophilic leukemia (RBL) and mouse C57 cells respond to IgE/antigen complexes by degranulation. Treatment of these cells with 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), (10-100 nM) for 24-48 h enhanced IgE/antigen-induced exocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22926943486a7ab609c5582b017a5d2d
https://pubmed.ncbi.nlm.nih.gov/9783902
https://pubmed.ncbi.nlm.nih.gov/9783902
Autor:
K G, Saag, R, Emkey, T J, Schnitzer, J P, Brown, F, Hawkins, S, Goemaere, G, Thamsborg, U A, Liberman, P D, Delmas, M P, Malice, M, Czachur, A G, Daifotis
Publikováno v:
The New England journal of medicine. 339(5)
Osteoporosis is a common complication of long-term glucocorticoid therapy for which there is no well-proved preventive or restorative treatment.We carried out two 48-week, randomized, placebo-controlled studies of two doses of alendronate in 477 men
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::098e312bef24731a214a443d497c31c8
https://pubmed.ncbi.nlm.nih.gov/10928896
https://pubmed.ncbi.nlm.nih.gov/10928896