Zobrazeno 1 - 10
of 397
pro vyhledávání: '"U‒Ser Jeng"'
Autor:
Tien-Chang Lin, Orion Shih, Tien-Ying Tsai, Yi-Qi Yeh, Kuei-Fen Liao, Bradley W. Mansel, Ying-Jen Shiu, Chi-Fon Chang, An-Chung Su, Yun-Ru Chen, U-Ser Jeng
Publikováno v:
IUCrJ, Vol 11, Iss 5, Pp 849-858 (2024)
The aberrant fibrillization of huntingtin exon 1 (Httex1) characterized by an expanded polyglutamine (polyQ) tract is a defining feature of Huntington's disease, a neurodegenerative disorder. Recent investigations underscore the involvement of a smal
Externí odkaz:
https://doaj.org/article/209dc44d9cfb417082cdde097083b7a8
Autor:
Shen Wang, Chun-Hsiang Huang, Te-Sheng Lin, Yi-Qi Yeh, Yun-Sheng Fan, Si-Wei Wang, Hsi-Ching Tseng, Shing-Jong Huang, Yu-Yang Chang, U-Ser Jeng, Chung-I Chang, Shiou-Ru Tzeng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Peptidoglycan (PG) sacculi surround the cytoplasmic membrane, maintaining cell integrity by withstanding internal turgor pressure. During cell growth, PG endopeptidases cleave the crosslinks of the fully closed sacculi, allowing for the inco
Externí odkaz:
https://doaj.org/article/9dc6763084454188a6c316c6ffe9a403
Autor:
Mei-Hui Hou, Yu-Chuan Wang, Chia-Shin Yang, Kuei-Fen Liao, Je-Wei Chang, Orion Shih, Yi-Qi Yeh, Manoj Kumar Sriramoju, Tzu-Wen Weng, U-Ser Jeng, Shang-Te Danny Hsu, Yeh Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The cyclic GMP-AMP synthase (cGAS)/stimulator of interferon gene (STING) signaling pathway plays a critical protective role against viral infections. Metazoan STING undergoes multilayers of regulation to ensure specific signal transduction.
Externí odkaz:
https://doaj.org/article/ca986528205f4ec69d407be288059425
Autor:
Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, Chiung-Mei Chen, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, Yun-Ru Chen
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Abnormal polyglutamine (polyQ) expansion and fibrillization occur in Huntington’s disease (HD). Amyloid modifier SERF enhances amyloid formation, but the underlying mechanism is not revealed. Here, the fibrillization and toxicity effect of
Externí odkaz:
https://doaj.org/article/6e87385b553749fe86bdfe7efeea0311
Autor:
Hong Thuy Vy Nguyen, Xiaorui Chen, Claudia Parada, An-Chi Luo, Orion Shih, U-Ser Jeng, Chia-Ying Huang, Yu-Ling Shih, Che Ma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
The FtsB-FtsL-FtsQ complex is essential for regulating cell wall synthesis during bacterial cell division. Here, authors report the full-length trimeric structure showing a tilted V-shaped conformation and suggest an allosteric regulatory mechanism.
Externí odkaz:
https://doaj.org/article/ea9125c01b5f4c17b41219e5cbe79619
Autor:
Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, Chiung-Mei Chen, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, Yun-Ru Chen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/23195256cee845cba07ecc78881ccb80
Autor:
Wei-Jiun Tsai, Yi-Hsin Lai, Yong-An Shi, Michal Hammel, Anthony P. Duff, Andrew E. Whitten, Karyn L. Wilde, Chun-Ming Wu, Robert Knott, U-Ser Jeng, Chia-Yu Kang, Chih-Yu Hsu, Jian-Li Wu, Pei-Jane Tsai, Chuan Chiang-Ni, Jiunn-Jong Wu, Yee-Shin Lin, Ching-Chuan Liu, Toshiya Senda, Shuying Wang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Structural and mutational analyses reveal interactions between NAD+-glycohydrolase and Streptolysin O critical for Group A Streptococcus virulence, validated in a murine infection model.
Externí odkaz:
https://doaj.org/article/2cd8522dbd71452f8c5716972482d2f5
Autor:
Yi-Cheng Lai, Bradley W. Mansel, Chun-Yu Chen, Chih-Ying Liu, Yu-Hsiang Chen, Chun-Jen Su, U-Ser Jeng, Hsin-Lung Chen
Publikováno v:
Giant, Vol 14, Iss , Pp 100147- (2023)
The electrostatic interaction between of poly(amidoamine) (PAMAM) G9 dendrimer and an achiral surfactant, dodecylbenzenesulfonic acid (DBSA), leads to the formation of nucleosome-like structure, where the globular dendrimer molecule directs the DBSA
Externí odkaz:
https://doaj.org/article/6518fdc9ece447b9b588bc706f4cba60
Autor:
Tien-Ying Tsai, Chun-Yu Chen, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, Chiung-Mei Chen, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, Yun-Ru Chen
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/f4ca8793b2a14fec90efec80ad653915
Autor:
Jia-Ning Hsu, Jyun-Siao Chen, Shan-Meng Lin, Jhen-Yi Hong, Yi-Jheng Chen, U-Ser Jeng, Shun-Yuan Luo, Ming-Hon Hou
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/f0fafd50850343c09f607447d4e5583b