Zobrazeno 1 - 10
of 31
pro vyhledávání: '"U‐K. Craig"'
Publikováno v:
Neurology. 69:196-199
We sought to determine if Chamorro individuals with a family history of Guam dementia (GD) or Parkinson dementia complex (PDC) exhibit presymptomatic brain MRI changes. Sixty-six Chamorro subjects had neurocognitive assessment and volumetric MRI. MRI
Autor:
Amy R. Borenstein, Anthony Gamst, P. Brooks, Gerard D. Schellenberg, J. A. Kaye, Douglas Galasko, R. Adonay, David P. Salmon, Leon J. Thal, Lisa C. Silbert, John M Olichney, U. K. Craig
Publikováno v:
Neurology. 68:1772-1781
Objectives: To estimate the prevalence of dementia and its clinical subtypes among Chamorros on Guam aged 65 years or older and to examine associations with age, gender, education, and APOE genotype. Background: Chamorros, the indigenous people of Gu
Autor:
Bryce A. Pasqualotto, Christopher A. Shaw, J. M. B. Wilson, Lidong Liu, Yu Tian Wang, Raymond J. Andersen, Iraj Khabazian, U‐K. Craig, Seung U. Kim, David E. Williams, Jaswinder S. Bains, A. Nagai, J. Cheung, Steven L. Pelech
Publikováno v:
Journal of Neurochemistry. 82:516-528
The factors responsible for ALS-parkinsonism dementia complex (ALS-PDC), the unique neurological disorder of Guam, remain unresolved, but identification of causal factors could lead to clues for related neurodegenerative disorders elsewhere. Earlier
Autor:
Anthony Gamst, W. C. Wiederholt, Ralph M. Garruto, Jose M. Torres, Chris C. Plato, U. K. Craig, Douglas Galasko, M. Plato
Publikováno v:
Neurology. 58:765-773
Background: It was noticed in the mid-1950s that the incidence of ALS and parkinsonism–dementia complex (PDC) were much higher on Guam than anywhere else in the world. In 1958, a registry of patients and controls was established to ascertain the fa
Publikováno v:
Neurology. 58:90-97
In the 1950s, high-incidence ALS and Parkinson-dementia complex (PDC) were identified among Chamorros, the native inhabitants of Guam. Brains of patients with these syndromes showed widespread neurofibrillary tangles. Although ALS and PDC were report
Publikováno v:
Acta Neuropathologica. 99:73-80
A 58-year-old Chamorro female patient, who died in 1993, was examined clinicopathologically. At the age of 51, she suffered from hemiparkinsonism, then bradykinesia, rigidity without tremor, and dementia. Extrapyramidal symptoms developed, and at the
Autor:
R. C. Petersen, U. K. Craig, C. Esteban-Santillan, V. A. Lennon, L. T. Kurland, Demetrius M. Maraganore, J. E. Ahlskog, S. C. Waring
Publikováno v:
Neurology. 48:1356-1362
On the western Pacific island of Guam, parkinsonism, dementia, and amyotrophic lateral sclerosis are highly prevalent but the cause is not known. To assess the possibility that the pathologic process extends beyond the nervous system, we studied pati
Autor:
Cyrus P. Zabetian, U. K. Craig, Gerard D. Schellenberg, Douglas Galasko, Kiyomitsu Oyanagi, Beth A. Dombroski, Ralph M. Garruto, Ignacio F. Mata
Importance High-prevalence foci of amyotrophic lateral sclerosis (ALS) and parkinsonism-dementia complex (PDC) exist in Japanese on the Kii Peninsula of Japan and in the Chamorros of Guam. Clinical and neuropathologic similarities suggest that the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8b71d5c8d0c36d9cdc972cee2f6cd0
https://europepmc.org/articles/PMC3771869/
https://europepmc.org/articles/PMC3771869/
Autor:
U. K. Craig, Ellen J. Steinbart, Purnima Desai Sundar, Thomas D. Bird, Chang En Yu, Ralph M. Garruto, Ellen M. Wijsman, Weiva Sieh, Gerard D. Schellenberg, Douglas Galasko, Kiyomitsu Oyanagi
Publikováno v:
Human molecular genetics. 16(3)
Unusual forms of amyotrophic lateral sclerosis (ALS-G), Parkinsonism dementia complex (PDC-G) and Guam dementia (GD) are found in Chamorros, the indigenous people of Guam. Neurofibrillary tangles composed of hyperphosphorylated tau are a neuropatholo
Publikováno v:
Neuromolecular medicine. 3(2)
Glutamate transporter proteins appear crucial to controlling levels of glutamate in the central nervous system (CNS). Abnormal and/or decreased levels of various transporters have been observed in amyotrophic lateral sclerosis (ALS) and Alzheimer's d