Zobrazeno 1 - 10
of 117
pro vyhledávání: '"U, Mårtensson"'
Autor:
Kim Nguyen Doan, Alexander Grevel, Christoph U. Mårtensson, Lars Ellenrieder, Nicolas Thornton, Lena-Sophie Wenz, Łukasz Opaliński, Bernard Guiard, Nikolaus Pfanner, Thomas Becker
Publikováno v:
Cell Reports, Vol 31, Iss 4, Pp - (2020)
Summary: The mitochondrial outer membrane contains integral proteins with α-helical membrane anchors or a transmembrane β-barrel. The translocase of the outer membrane (TOM) cooperates with the sorting and assembly machinery (SAM) in the import of
Externí odkaz:
https://doaj.org/article/372cd7f158e048d6b4e2bc4a61552a3a
Akademický článek
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Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2018)
Impairment of the dopaminergic (DA) system is a common cause of several movement disorders including Parkinson’s disease (PD), however, little is known about the underlying disease mechanisms. The recent development of stem-cell-based protocols for
Externí odkaz:
https://doaj.org/article/fb9dd715c35440eb86727744d779e585
Autor:
Thomas Becker, Bettina Warscheid, Nicole Zufall, Kim Nguyen Doan, Jiyao Song, Lars Ellenrieder, Alessia Floerchinger, Silke Oeljeklaus, Felix Boos, Chantal Priesnitz, Christoph U. Mårtensson
Publikováno v:
Nature. 569:679-683
Mitochondrial biogenesis and functions depend on the import of precursor proteins via the 'translocase of the outer membrane' (TOM complex). Defects in protein import lead to an accumulation of mitochondrial precursor proteins that induces a range of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399a73f4d6baf7d2a309b3e55acded9b
https://doi.org/10.1038/s41586-019-1227-y
https://doi.org/10.1038/s41586-019-1227-y
Autor:
Bernard Guiard, Nikolaus Pfanner, Thomas Becker, Christoph U. Mårtensson, Kim Nguyen Doan, Lars Ellenrieder, Nicolas Thornton, Alexander Grevel, Lena-Sophie Wenz, Łukasz Opaliński
Publikováno v:
Cell Reports, Vol 31, Iss 4, Pp-(2020)
Summary: The mitochondrial outer membrane contains integral proteins with α-helical membrane anchors or a transmembrane β-barrel. The translocase of the outer membrane (TOM) cooperates with the sorting and assembly machinery (SAM) in the import of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953c2ec40ccfb32e494938be9ab37e12
https://pubmed.ncbi.nlm.nih.gov/32348752
https://pubmed.ncbi.nlm.nih.gov/32348752
Autor:
Max-Hinderk Schuler, Francesca Di Bartolomeo, Guenther Daum, Christoph U. Mårtensson, Thomas Becker
Publikováno v:
Journal of Biological Chemistry. 291:18718-18729
Two protein translocases transport precursor proteins into or across the inner mitochondrial membrane. The presequence translocase (TIM23 complex) sorts precursor proteins with a cleavable presequence either into the matrix or into the inner membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dcd98a2ad8f90dfafc45657de0e8aa
https://doi.org/10.1074/jbc.m116.722694
https://doi.org/10.1074/jbc.m116.722694
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 11 (2018)
Frontiers in Cellular Neuroscience, Vol 11 (2018)
Impairment of the dopaminergic (DA) system is a common cause of several movement disorders including Parkinson’s disease (PD), however, little is known about the underlying disease mechanisms. The recent development of stem-cell-based protocols for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9719b65dfba1808c5d67a0ebfee99869
Autor:
Nicole Zufall, Jiyao Song, Nils Wiedemann, Lena Böttinger, Thomas Becker, Christoph U. Mårtensson
Publikováno v:
Molecular Biology of the Cell
Mitochondrial cytochrome bc1 complex and cytochrome c oxidase associate in respiratory chain supercomplexes. We identified a specific association of the iron–sulfur cluster biogenesis desulfurase with the respiratory chain supercomplexes. Our findi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674e4d57659e83f1b89805db432547d5
Publikováno v:
Biological Chemistry. 396:1199-1213
Proteins of the mitochondrial outer membrane are synthesized as precursors on cytosolic ribosomes and sorted via internal targeting sequences to mitochondria. Two different types of integral outer membrane proteins exist: proteins with a transmembran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85270222f0b7446793193c34859e5b8
https://doi.org/10.1515/hsz-2015-0170
https://doi.org/10.1515/hsz-2015-0170
Autor:
Thomas Becker, Christoph U. Mårtensson
Publikováno v:
Trends in cell biology. 27(10)
The carrier translocase (TIM22 complex) inserts hydrophobic proteins into the mitochondrial inner membrane. Recently, the acylglycerol kinase (AGK) mutated in Sengers syndrome was identified as a novel subunit of the human TIM22 complex. This finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42e552654b3018146b88729937f7c70
https://pubmed.ncbi.nlm.nih.gov/28867158
https://pubmed.ncbi.nlm.nih.gov/28867158